Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors

• An engineered tumor organoid model reveals cellular identity and signaling trajectories underlying SFPQ-TFE3 driven translocation RCC

  2025 iScience article Medicine Renal cell carcinoma treatment Open access

  5

  citations
• Understanding developing kidneys and Wilms tumors one cell at a time

  2025 Current topics in developmental biology/Current Topics in Developmental Biology book-chapter Biochemistry, Genetics and Molecular Biology Renal and related cancers

  1

  citations
• Identification of kidney cell types in scRNA-seq and snRNA-seq data using machine learning algorithms

  2024 Heliyon article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  3

  citations
• Single-cell transcriptional profiling of clear cell renal cell carcinoma reveals a tumor-associated endothelial tip cell phenotype

  2024 Communications Biology article Medicine Renal cell carcinoma treatment Open access

  49

  citations
• Identification of Kidney Cell Types in scRNA-seq and snRNA-seq Data Using Machine Learning Algorithms

  2024 Research Square preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  2

  citations
• An engineered tumor organoid model reveals cellular identity and signaling trajectories underlying translocation RCC

  2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Renal cell carcinoma treatment Open access

  0

  citations
• Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression

  2022 Nature Communications article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access

  65

  citations
• Spatial dynamic metabolomics identifies metabolic cell fate trajectories in human kidney differentiation

  2022 Cell stem cell article Biochemistry, Genetics and Molecular Biology Renal and related cancers Open access

  126

  citations
• Mapping the human kidney using single-cell genomics

  2022 Nature Reviews Nephrology review Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  71

  citations
• Nitrogen partitioning between branched-chain amino acids and urea cycle enzymes sustains renal cancer progression

  2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access

  5

  citations
• Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencing

  2021 npj Regenerative Medicine article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  60

  citations
• Revealing the spatio-phenotypic patterning of cells in healthy and tumor tissues with mLSR-3D and STAPL-3D

  2021 Nature Biotechnology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access cited by 4 patents

  34

  citations
• Embryonic Kidney Development, Stem Cells and the Origin of Wilms Tumor

  2021 Genes article Biochemistry, Genetics and Molecular Biology Renal and related cancers Open access

  41

  citations
• Decoding myofibroblast origins in human kidney fibrosis

  2020 Nature article Medicine Chronic Kidney Disease and Diabetes Open access cited by 5 patents

  801

  citations
• Experimental and computational technologies to dissect the kidney at the single-cell level

  2020 Nephrology Dialysis Transplantation article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access

  12

  citations
• An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

  2020 Cancer Cell article Biochemistry, Genetics and Molecular Biology Angiogenesis and VEGF in Cancer Open access

  492

  citations

16 results