The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

• p62/SQSTM1-KEAP1 complex prevents clearance of ubiquitinated Z alpha-1 antitrypsin and aggravates liver proteotoxicity

  2026 Journal of Biological Chemistry article Biochemistry, Genetics and Molecular Biology Endoplasmic Reticulum Stress and Disease Open access

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• Establishment of a 3D Multicellular HCC Tumor Spheroid Model to Unravel Nrf2’s Influence on the Tumor Immune Microenvironment

  2026 Bioengineering article Immunology and Microbiology Immune cells in cancer Open access

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• Deciphering the quantitative relationship between NRF2 and SRXN1 through semi-mechanistic computational modeling

  2025 Toxicology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access

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• Imaging-based temporal dynamics of electrophile-induced NRF2 signaling in liver cells identifies adaptive versus adverse repeated exposure conditions

  2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress

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• Mathematical modelling reveals compound-specific stress pathway activity

  2025 Toxicology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access

  4

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• Luteolin Induces Nrf2 Activity in C2C12 Cells: Implications for Muscle Health

  2025 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access

  9

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• Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression

  2024 Nature Communications article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access

  62

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• Pharmacological effects of methysticin and L-sulforaphane through the Nrf2/ARE signaling pathway in MLO-Y4 osteocytes: in vitro study

  2024 Annals of Anatomy - Anatomischer Anzeiger article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access

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• Nrf2 induces malignant transformation of hepatic progenitor cells by inducing β-catenin expression

  2022 Redox Biology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access

  11

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• Mapping the dynamics of Nrf2 antioxidant and NFκB inflammatory responses by soft electrophilic chemicals in human liver cells defines the transition from adaptive to adverse responses

  2022 Toxicology in Vitro article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access

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• Sulforaphane Exerts Beneficial Immunomodulatory Effects on Liver Tissue via a Nrf2 Pathway-Related Mechanism in a Murine Model of Hemorrhagic Shock and Resuscitation

  2022 Frontiers in Immunology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access

  19

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• The Eco-Exposome Concept: Supporting an Integrated Assessment of Mixtures of Environmental Chemicals

  2021 Environmental Toxicology and Chemistry article Environmental Science Environmental Toxicology and Ecotoxicology Open access

  55

  citations
• Impact of Zika Virus Infection on Human Neural Stem Cell MicroRNA Signatures

  2020 Viruses article Medicine Mosquito-borne diseases and control Open access

  26

  citations

13 results