The CCP4 suite: programs for protein crystallography

• Ultrafast structural changes direct the first molecular events of vision

  2023 Nature article Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access

  134

  citations
• Cutting Edge: Unconventional CD8+ T Cell Recognition of a Naturally Occurring HLA-A*02:01–Restricted 20mer Epitope

  2022 The Journal of Immunology article Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access

  3

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• Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation

  2022 Science Advances article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access

  77

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• Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death

  2021 Computational and Structural Biotechnology Journal article Neuroscience Genetic Neurodegenerative Diseases Open access

  19

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• ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes

  2021 Cell Reports article Biochemistry, Genetics and Molecular Biology Wnt/β-catenin signaling in development and cancer Open access

  29

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• Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death

  2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Genetic Neurodegenerative Diseases Open access

  0

  citations
• ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes

  2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Wnt/β-catenin signaling in development and cancer Open access

  2

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• Ectopic positioning of the cell division plane is associated with single amino acid substitutions in the FtsZ-recruiting SsgB in Streptomyces

  2021 Open Biology article Biochemistry, Genetics and Molecular Biology Bacterial Genetics and Biotechnology Open access

  9

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• How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition—The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine

  2020 Molecules article Biochemistry, Genetics and Molecular Biology Synthesis and bioactivity of alkaloids Open access

  14

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• Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway

  2020 ACS Chemical Biology article Medicine Microbial Natural Products and Biosynthesis Open access

  14

  citations
• Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown

  2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access

  149

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• Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation

  2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Fungal and yeast genetics research Open access

  66

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• Structure-Based Design of Prefusion-Stabilized Filovirus Glycoprotein Trimers

  2020 Cell Reports article Medicine Viral Infections and Outbreaks Research Open access cited by 15 patents

  80

  citations

13 results