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Charles River Laboratories (Netherlands) Sign in to save

133 stored papers · Search its papers → · Its authors →

Papers 133

Keeping modelling notebooks with TRACE: Good for you and good for environmental research and management support
2020 Environmental Modelling & Software article Decision Sciences Scientific Computing and Data Management Open access

67

citations
Opportunities for use of one species for longer-term toxicology testing during drug development: A cross-industry evaluation
2020 Regulatory Toxicology and Pharmacology article Veterinary Animal testing and alternatives Open access

43

citations
Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington's disease
2021 Journal of Neurochemistry article Neuroscience Tryptophan and brain disorders Open access

36

citations
Adversity Considerations for Thyroid Follicular Cell Hypertrophy and Hyperplasia in Nonclinical Toxicity Studies: Results From the 6th ESTP International Expert Workshop
2020 Toxicologic Pathology article Immunology and Microbiology Immunotoxicology and immune responses

34

citations
Pharmacokinetics of single and repeated oral doses of pregabalin oral solution formulation in cats
2022 Journal of Veterinary Pharmacology and Therapeutics article Veterinary Veterinary Pharmacology and Anesthesia Open access

34

citations
Developing HDAC4-Selective Protein Degraders To Investigate the Role of HDAC4 in Huntington’s Disease Pathology
2022 Journal of Medicinal Chemistry article Neuroscience Genetic Neurodegenerative Diseases Open access

34

citations
Extrahepatic metabolism of ibrutinib
2020 Investigational New Drugs article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access

28

citations
A minimal metadata set (MNMS) to repurpose nonclinical in vivo data for biomedical research
2024 Lab Animal article Computer Science Research Data Management Practices Open access

24

citations
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – part II: how can key events of relevant adverse outcome pathways be addressed in toxicological assessments?
2021 Critical Reviews in Toxicology article Environmental Science Effects and risks of endocrine disrupting chemicals Open access

23

citations
The influence of alkyl substitution on the in vitro metabolism and mutagenicity of benzo[a]pyrene
2022 Chemico-Biological Interactions article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access

20

citations
Bioaccessibility as a determining factor in the bioavailability and toxicokinetics of cadmium compounds
2021 Toxicology article Environmental Science Heavy Metal Exposure and Toxicity

20

citations
Scientific and Regulatory Policy Committee Best Practices: Documentation of Sexual Maturity by Microscopic Evaluation in Nonclinical Safety Studies
2021 Toxicologic Pathology article Veterinary Animal testing and alternatives

19

citations
Investigating brain uptake of a non-targeting monoclonal antibody after intravenous and intracerebroventricular administration
2022 Frontiers in Pharmacology article Neuroscience Barrier Structure and Function Studies Open access

19

citations
Evaluation of 3D Human Intestinal Organoids as a Platform for EV-A71 Antiviral Drug Discovery
2023 Cells article Medicine Viral Infections and Immunology Research Open access

19

citations
HESI GTTC ring trial: Concordance between Ames and rodent carcinogenicity outcomes for N-nitrosamines (NAs) with rat and hamster metabolic conditions
2025 Regulatory Toxicology and Pharmacology article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access

15

citations
Human relevance of in vivo and in vitro skin irritation tests for hazard classification of pesticides
2024 Cutaneous and Ocular Toxicology article Veterinary Animal testing and alternatives Open access

14

citations
Zebrafish Embryo Developmental Toxicity Assay (ZEDTA) for Regulatory Testing—Protocol Optimization and Historical Control Data
2025 Toxics article Biochemistry, Genetics and Molecular Biology Zebrafish Biomedical Research Applications Open access

12

citations
EU roadmap for phasing out animal testing for chemical safety assessments: Recommendations from a multi-stakeholder roundtable
2025 ALTEX article Veterinary Animal testing and alternatives Open access

12

citations
Assessment of the utility of the novel Phenion® full thickness human skin model for detecting the skin irritation potential of antimicrobial cleaning products
2023 Toxicology in Vitro article Veterinary Animal testing and alternatives Open access

11

citations
Subchronic feeding, allergenicity, and genotoxicity safety evaluations of single strain bacterial protein
2022 Food and Chemical Toxicology article Agricultural and Biological Sciences Agricultural safety and regulations Open access

11

citations

Most cited authors