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High-dimensional single-cell analysis of human natural killer cell heterogeneity2024 Nature Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Lucas Rebuffet, Janine E. Melsen, Bertrand Escalière, Daniela Basurto-Lozada, Avinash Bhandoola, Niklas K. Björkström, +21 more
278citations -
NKG2A is a late immune checkpoint on CD8 T cells and marks repeated stimulation and cell division2021 International Journal of Cancer article Immunology and Microbiology Immune Cell Function and Interaction Open access
Linda Borst, Marjolein Sluijter, Gregor Sturm, Pornpimol Charoentong, Saskia J A M Santegoets, Mandy van Gulijk, +8 more
58citations -
The Molecular and Functional Characteristics of HLA-G and the Interaction with Its Receptors: Where to Intervene for Cancer Immunotherapy?2020 International Journal of Molecular Sciences article Immunology and Microbiology Immune Cell Function and Interaction Open access
Jiji V. D. Attia, Charlotte E. Dessens, Ricky B. van de Water, Ruben D. Houvast, Peter J.K. Kuppen, Daniëlle Krijgsman
57citations -
Anti-PD-1 antibody increases NK cell cytotoxicity towards nasopharyngeal carcinoma cells in the context of chemotherapy-induced upregulation of PD-1 and PD-L12020 Cancer Immunology Immunotherapy article Immunology and Microbiology Immune Cell Function and Interaction Open access cited by 1 patent
Anna M. Makowska, Selina Meier, Lian Shen, Pierre Busson, Valentin M. D. Baloche, Udo Kontny
46citations -
T cell receptor engineering of primary NK cells to therapeutically target tumors and tumor immune evasion2022 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology Immune Cell Function and Interaction Open access
Laura T. Morton, Tassilo L A Wachsmann, Miranda H. Meeuwsen, Anne K. Wouters, Dennis F.G. Remst, Marleen M. van Loenen, +2 more
34citations -
Expression of NK cell receptor ligands in primary colorectal cancer tissue in relation to the phenotype of circulating NK- and NKT cells, and clinical outcome2020 Molecular Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Daniëlle Krijgsman, Jessica P Roelands, Morten Nørgaard Andersen, Cornelia H.L.A. Wieringa, Rob A.�E.�M. Tollenaar, Wouter Hendrickx, +3 more
28citations -
Antibody-dependent cellular cytotoxicity-inducing antibodies enhance the natural killer cell anti-cancer response against patient-derived pancreatic cancer organoids2023 Frontiers in Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Nicky A. Beelen, Merel R. Aberle, Virginia Bruno, Steven W.M. Olde Damink, Gerard M.J. Bos, Sander S. Rensen, +1 more
23citations -
The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent2023 Cell Reports article Immunology and Microbiology Immune Cell Function and Interaction Open access
Jim Middelburg, Soroush Ghaffari, Tom A. W. Schoufour, Marjolein Sluijter, Gaby Schaap, Büşra Göynük, +14 more
20citations -
Rapid dose-dependent Natural Killer (NK) cell modulation and cytokine responses following human rVSV-ZEBOV Ebolavirus vaccination2020 npj Vaccines article Immunology and Microbiology Immune Cell Function and Interaction Open access
David Pejoski, Casimir de Rham, Paola Martinez-Murillo, Francesco Santoro, Floriane Auderset, Donata Medaglini, +38 more
20citations -
Ebola virus glycoprotein stimulates IL-18–dependent natural killer cell responses2020 Journal of Clinical Investigation article Immunology and Microbiology Immune Cell Function and Interaction Open access
Helen R. Wagstaffe, Elizabeth Clutterbuck, Viki Bockstal, Jeroen N. Stoop, Kerstin Lühn, Macaya Douoguih, +5 more
20citations -
KIR3DS1 directs NK cell–mediated protection against human adenovirus infections2021 Science Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Johannes M. Jung, Wilhelm Ching, Martin E. Baumdick, Helga Hofmann-Sieber, Jens B. Bosse, Tobias Koyro, +22 more
18citations -
Single-cell transcriptomics in bone marrow delineates CD56dimGranzymeK+ subset as intermediate stage in NK cell differentiation2022 Frontiers in Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Janine E. Melsen, Monique M. van Ostaijen-ten Dam, Dorenda J. A. Schoorl, Pieter J. Schol, Daphne A. L. van den Homberg, Arjan C. Lankester, +2 more
17citations -
Donor KIR genotype based outcome prediction after allogeneic stem cell transplantation: no land in sight2024 Frontiers in Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Johannes Schetelig, Henning Baldauf, Falk Heidenreich, Jorinde Desiree Hoogenboom, Stephen R. Spellman, Alexander Kulagin, +23 more
14citations -
HLA-E/peptide complexes differentially interact with NKG2A/CD94 and T cell receptors2025 The Journal of Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Linda Voogd, Remco L. van den Broek, Marjolein van Wolfswinkel, Kees L. M. C. Franken, Paula Ruibal, Willem Jespers, +5 more
10citations -
NK Cell-Dependent Antibody-Mediated Immunotherapy Is Improved In Vitro and In Vivo When Combined with Agonists for Toll-like Receptor 2 in Head and Neck Cancer Models2021 International Journal of Molecular Sciences article Immunology and Microbiology Immune Cell Function and Interaction Open access
Mandy Gruijs, Sonja H. Ganzevles, Marijke Stigter‐van Walsum, Richard van der Mast, Monique M. van Ostaijen-ten Dam, Cornelis W. Tuk, +6 more
8citations -
A human NK cell progenitor that originates in the thymus and generates KIR + NKG2A − NK cells2025 Science Advances article Immunology and Microbiology Immune Cell Function and Interaction Open access
Sujal Ghosh, Michael Scheid, Lea Graafen, Nadine Scherenschlich, Sandra Weinhold, Katharina Raba, +9 more
7citations -
A Single-Domain TCR-like Antibody Selective for the Qa-1b/Qdm Peptide Complex Enhances Tumoricidal Activity of NK Cells via Blocking the NKG2A Immune Checkpoint2022 The Journal of Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Soroush Ghaffari, Katherine Upchurch, Susanne Gimlin, Trivendra Tripathi, Marjolein Sluijter, Jim Middelburg, +2 more
7citations -
Protocol for Isolation, Stimulation and Functional Profiling of Primary and iPSC-derived Human NK Cells2020 BIO-PROTOCOL article Immunology and Microbiology Immune Cell Function and Interaction Open access
Janine E. Melsen, Maria Themeli, M. van Dam, Els van Beelen, Gertjan Lugthart, Rob C. Hoeben, +2 more
7citations -
Comment to: Single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia2021 Cellular and Molecular Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Janine E. Melsen, Gertjan Lugthart, Monique M. van Ostaijen-ten Dam, Marco W. Schilham
6citations