-
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Sonia H Shah, Albert Carl Henry, Carolina Roselli, Honghuang Lin, Garðar Sveinbjörnsson, Ghazaleh Fatemifar, +88 more
845citations -
Multivariate genomic scan implicates novel loci and haem metabolism in human ageing2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access cited by 2 patents
Paul R. H. J. Timmers, James F. Wilson, Peter K. Joshi, Joris Deelen
145citations -
Heritability estimates for 361 blood metabolites across 40 genome-wide association studies2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Fiona A. Hagenbeek, René Pool, Jenny van Dongen, Harmen H. M. Draisma, Jouke‐Jan Hottenga, Gonneke A. H. M. Willemsen, +62 more
120citations -
Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications2024 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Rosalie B. T. M. Sterenborg, Inga Steinbrenner, Yong Li, Melissa N. Bujnis, Tatsuhiko Naito, Eirini Marouli, +92 more
80citations -
Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits2022 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Lili Liu, Atlas Khan, Elena Sánchez, Francesca Zanoni, Yifu Li, Nicholas J. Steers, +46 more
62citations -
Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Adriaan van der Graaf, Annique Claringbould, Antoine Rimbert, Bastiaan T. Heijmans, Peter A.C. ’t Hoen, Joyce B. J. van Meurs, +6 more
61citations -
Coding and regulatory variants are associated with serum protein levels and disease2022 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Valur Emilsson, Valborg Guðmundsdóttir, Alexander Guðjónsson, Þórarinn Jónmundsson, Brynjolfur G. Jonsson, Mohd Anisul Karim, +10 more
55citations -
OTTERS: a powerful TWAS framework leveraging summary-level reference data2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Qile Dai, Geyu Zhou, Hongyu Zhao, Urmo Võsa, Lude Franke, Alexis J. Battle, +79 more
52citations -
Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Andrew Anand Brown, Juan J. Fernandez-Tajes, Mun‐Gwan Hong, Caroline Brorsson, Robert Wilhelm Koivula, David Davtian, +93 more
44citations -
Genetic insights into resting heart rate and its role in cardiovascular disease2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Yordi J. van de Vegte, Ruben N. Eppinga, M. Yldau van der Ende, Yanick Paco Hagemeijer, Yuvaraj Mahendran, Elias Salfati, +94 more
36citations -
Human-lineage-specific genomic elements are associated with neurodegenerative disease and APOE transcript usage2021 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Zhongbo Chen, David Zhang, Regina Hertfelder Reynolds, Emil Karl Gustavsson, Sonia García-Ruiz, Karishma D’Sa, +93 more
23citations -
MR-link-2: pleiotropy robust cis Mendelian randomization validated in three independent reference datasets of causality2025 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Adriaan van der Graaf, Robert Warmerdam, Chiara Auwerx, Dorret Irene Boomsma, Evans K. Cheruiyot, Emma E. Davenport, +26 more
20citations -
Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Koen F. Dekkers, Roderick C. Slieker, Andreea Ioan‐Facsinay, Maarten van Iterson, M. Arfan Ikram, Marleen M. J. van Greevenbroek, +6 more
19citations -
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements2024 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Markus R. Scholz, Katrin Horn, Janne Pott, Matthias Wuttke, Andreas Kühnapfel, M. Kamal Nasr, +94 more
14citations -
A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Julian Petersen, Lukas Englmaier, Artem V. Artemov, Irina V. Poverennaya, Thibault Bouderlique, Ruslan M. Deviatiiarov, +36 more
7citations -
Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes2021 Nature Communications erratum Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Joris Deelen, Daniel S. Evans, Dan E. Arking, Niccoló Tesi, Marianne Nygaard, Xiaomin Liu, +76 more
6citations -
Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies2020 Nature Communications erratum Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Fiona A. Hagenbeek, René Pool, Jenny van Dongen, H. M. Draisma, Jouke‐Jan Hottenga, Gonneke A. H. M. Willemsen, +62 more
3citations -
Author Correction: Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits2023 Nature Communications erratum Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Lili Liu, Atlas Khan, Elena Sánchez, Francesca Zanoni, Yifu Li, Nicholas J. Steers, +46 more
2citations -
Publisher Correction: Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus2022 Nature Communications erratum Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
David Stacey, Lingyan Chen, Paulina J. Stanczyk, Joanna M. M. Howson, Amy M. Mason, Stephen Burgess, +88 more
1citations
19 results