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Perturbation of de novo lipogenesis hinders MERS-CoV assembly and release, but not the biogenesis of viral replication organelles2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access
Maria Soultsioti, Anja W. M. de Jong, Nienke J. Blomberg, Ali Taş, Martin A. Giera, Eric J. Snijder, +1 more
0citations -
Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication2023 Cellular and Molecular Life Sciences article Medicine Mosquito-borne diseases and control Open access
Sarah Krieg, Fabian Pott, Laura Potthoff, Maud Verheirstraeten, Mareike Bütepage, Alexandra Golzmann, +4 more
39citations -
Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis2023 PLoS Pathogens article Agricultural and Biological Sciences Animal Virus Infections Studies Open access
Ben A. Bailey-Elkin, Robert C. M. Knaap, Anuradha De Silva, Ilse M. Boekhoud, Sandra TM Mous, Niek van Vught, +4 more
10citations -
Vaccines based on replication incompetent Ad26 viral vectors: Standardized template with key considerations for a risk/benefit assessment2020 Vaccine article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 2 patents
Jerome H. H. V. Custers, Denny Kim, Maarten Leyssen, Marc Gurwith, Frank L. Tomaka, James S. Robertson, +10 more
84citations -
6′-β-Fluoro-Homoaristeromycin and 6′-Fluoro-Homoneplanocin A Are Potent Inhibitors of Chikungunya Virus Replication through Their Direct Effect on Viral Nonstructural Protein 12020 Antimicrobial Agents and Chemotherapy article Medicine Mosquito-borne diseases and control Open access
Bas M. Morren, Ali Taş, Irina C. Albulescu, Robin van Rijswijk, Dnyandev B. Jarhad, Young Sup Shin, +6 more
35citations -
SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology2020 Journal of General Virology article Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 17 patents
Natacha S. Ogando, Tim J. Dalebout, Jessika C. Zevenhoven-Dobbe, Ronald W.A.L. Limpens, Leon Caly, Julian D Druce, +5 more
557citations -
SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 17 patents
Natacha S. Ogando, Tim J. Dalebout, Jessika C. Zevenhoven-Dobbe, Ronald W.A.L. Limpens, Leon Caly, Julian D Druce, +5 more
70citations -
Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategies2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Mathematical and Theoretical Epidemiology and Ecology Models Open access
Carolin Zitzmann, Christopher Dächert, Bianca Schmid, Hilde M. van der Schaar, Martijn J. van Hemert, Alan S. Perelson, +4 more
0citations -
Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategies2023 PLoS Computational Biology article Medicine Mathematical and Theoretical Epidemiology and Ecology Models Open access
Carolin Zitzmann, Christopher Dächert, Bianca Schmid, Hilde M. van der Schaar, Martijn J. van Hemert, Alan S. Perelson, +4 more
14citations -
A molecular pore spans the double membrane of the coronavirus replication organelle2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access
Georg Wolff, Ronald W.A.L. Limpens, Jessika C. Zevenhoven-Dobbe, Ulrike Laugks, Shawn Q. Zheng, Anja W. M. de Jong, +6 more
49citations -
Conserved structural features of RNA export pores spanning the double membrane of arterivirus and coronavirus replication organelles2026 Journal of Virology article Agricultural and Biological Sciences Animal Virus Infections Studies Open access
Nina L. de Beijer, Ronald W.A.L. Limpens, Montserrat Bárcena, Eric J. Snijder
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Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo
Mariska van Huizen, Jonna R. Bloeme - ter Horst, Heidi L. M. De Gruyter, Paul P. Geurink, Gerbrand J. van der Heden van Noort, Robert C. M. Knaap, +8 more
23citations -
Double-membrane-spanning RNA export pores are a conserved feature in nidovirus replication organelles2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Agricultural and Biological Sciences Animal Virus Infections Studies Open access
Stanley Fronik, Georg Wolff, Ronald W.A.L. Limpens, A van der Meulen - de de Jong, Shawn Q. Zheng, David A. Agard, +3 more
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Suramin inhibits SARS-CoV-2 infection in cell culture by interfering with early steps of the replication cycle2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access
Clarisse Salgado Benvindo da Silva, Melissa Thaler, Ali Taş, Natacha S. Ogando, Peter J. Bredenbeek, Dennis K. Ninaber, +4 more
23citations -
Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug design2021 Nature Reviews Molecular Cell Biology review Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 2 patents
Brandon F. Malone, Nadya Urakova, Eric J. Snijder, Elizabeth A. Campbell
538citations -
Glucocorticoids Do Not Enhance BK Polyomavirus Replication in Human Renal Proximal Tubular Epithelial Cells In Vitro2026 Clinical and Translational Science article Medicine Polyomavirus and related diseases Open access
Wouter T. Moest, Reshma A. Lalai, Jurriën Prins, Aiko P. J. de Vries, Els Wessels, Cees van Kooten, +2 more
0citations