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Integrated risk assessment reveals low biological activity of RNA-based crop protection formulations across plant and non-target systems2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Insect Resistance and Genetics Open access
Moritz Dobrowitsch, Sandra Friedrich, Jonas Noetzold, Maria Bender, K. Rybak, Benjamin Moorlach, +9 more
0citations -
RNA sequencing reveals interacting key determinants of osteoarthritis acting in subchondral bone and articular cartilage2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Osteoarthritis Treatment and Mechanisms Open access
Margo Tuerlings, Marcella van Hoolwerff, Evelyn Houtman, H. Eka D. Suchiman, Nico Lakenberg, Hailiang Mei, +5 more
6citations -
Establishment and characterization of a new Pseudomonas aeruginosa infection model using 2D airway organoids and dual RNA sequencing2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Bacterial biofilms and quorum sensing Open access
Cayetano Pleguezuelos‐Manzano, Wouter A. G. Beenker, Gijs J. F. van Son, Harry Begthel, Gimano D. Amatngalim, Jeffrey Matthijn Beekman, +2 more
4citations -
CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Ida Höijer, Anastasia Emmanouilidou, Rebecka Östlund, Robin van Schendel, Selma Bozorgpana, Lars Feuk, +3 more
0citations -
Benchmarking computational methods for B-cell receptor reconstruction from single-cell RNA-seq data2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Tommaso Andreani, Linda M. Slot, Samuel Gabillard, Carsten Struebing, Claus Reimertz, Yaligara Veeranagouda, +6 more
4citations -
Genome-wide mapping of therapeutically-relevant SARS-CoV-2 RNA structures2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA and protein synthesis mechanisms Open access cited by 5 patents
Ilaria Manfredonia, Chandran Nithin, Almudena Ponce-Salvatierra, Pritha Ghosh, Tomasz K. Wirecki, Tycho Marinus, +5 more
22citations -
Single cell RNA sequence analysis of human bone marrow samples reveals new targets for isolation of skeletal stem cells using DNA-coated gold nanoparticles2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Mesenchymal stem cell research Open access
Elloise Matthews, Stuart Lanham, Maria Eleni Kyriazi, Konstantina Alexaki, Afaf Helmy El-Sagheer, Tom Brown, +5 more
3citations -
The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Shanna Dewaele, Louis Delhaye, Boél De Paepe, Eric James de Bony, Jilke De Wilde, Katrien Vanderheyden, +13 more
0citations -
CACTUS: integrating clonal architecture with genomic clustering and transcriptome profiling of single tumor cells2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Shadi Darvish Shafighi, Szymon M. Kiełbasa, Julieta Sepúlveda-Yáñez, Ramin Monajemi, Davy Cats, Hailiang Mei, +5 more
4citations -
SIngle cell level Genotyping Using scRna Data (SIGURD)2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Martin Graßhoff, Milena Kalmer, Nicolas Chatain, Kim Kricheldorf, Angela Maurer, Ralf Weiskirchen, +2 more
0citations -
Determining off-target effects of splice-switching antisense oligonucleotides using short read RNAseq in neuronally differentiated human induced pluripotent stem cells2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Elsa C. Kuijper, Linda M. van der Graaf, Barry A. Pepers, Mariana Guimarães Ramos, Sylvia Korhorn, Davy Cats, +4 more
1citations -
CaClust: linking genotype to transcriptional heterogeneity of follicular lymphoma using BCR and exomic variants2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Kazimierz Oksza-Orzechowski, Edwin Quinten, Shadi Darvish Shafighi, Szymon M. Kiełbasa, Hugo W van Kessel, Ruben A. L. de Groen, +6 more
1citations -
Roles for the long non-coding RNA Pax6os1 / PAX6-AS1 in pancreatic beta cell identity and function2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Pancreatic function and diabetes Open access
Livia López–Noriega, Rebecca Callingham, Aida Martínez-Sánchez, Sameena Nawaz, Grazia Pizza, Nejc Haberman, +13 more
6citations -
A scalable and equitable framework for target and patient prioritisation in rare disease antisense therapeutics2026 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genomics and Rare Diseases Open access
Ella F. Whittle, Kylie Montgomery, Carme Camps, Nour M. Elkhateeb, Catherine Ryan, Sara Aguti, +26 more
1citations -
“Universal Hyb-Seq kits capture considerable intraspecific variation: Less is more in herbarium-inclusive molecular ecology”2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetic diversity and population structure Open access
Yannick Woudstra, Anne‐Sophie Quatela, Cornelis A. M. Wagemaker, Slavica Ivanovic, Tanja Slotte, Patrick G. Meirmans, +2 more
1citations -
Sex-dependent gene regulation of human atherosclerotic plaques by DNA methylation and transcriptome integration points to smooth muscle cell involvement in women2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Robin J. G. Hartman, Marten A. Siemelink, Saskia Haitjema, Koen F. Dekkers, Lotte Slenders, Arjan Boltjes, +8 more
3citations -
OX40 agonism enhances efficacy of PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Guillaume Beyrend, Tetje Cornelia van der Sluis, Esmé T.I. van der Gracht, Tamim Abdelaal, Simon P. Jochems, Robert A. Belderbos, +16 more
0citations -
Single-cell and spatial transcriptomics resolve airway obliteration in bronchiolitis obliterans syndrome2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Transplantation: Methods and Outcomes Open access
Jannik Ruwisch, Hande Yilmaz, Leonard Christian, Lavinia Neubert, Lena Maureen Leiber, Annalea Brüggemann, +29 more
0citations -
ETV2 upregulation marks the specification of early cardiomyocytes and endothelial cells during co-differentiation2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Xu Cao, Maria Mircea, Gopala Krishna Yakala, Francijna E. van den Hil, Marcella Brescia, Hailiang Mei, +3 more
1citations -
Microbial Invasion and Immunosuppression Drives Adenoma Progression in Early Colorectal Cancer Development2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Wei Liang, Lisa Falk, Daniele Lucarelli, Philipp Putze, Amira Metwaly, Yiran Zheng, +13 more
0citations -
Deciphering the complex clonal heterogeneity of polycythemia vera and the response to interferon alpha2023 Research Square preprint Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Milena Kalmer, Martin Graßhoff, Tiago Maié, Kristina Pannen, Marcelo A. S. Toledo, Margherita Vieri, +13 more
2citations