Papers matching “systemic pharmacokinetics” 210
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Absolute Bioavailability of Oxaliplatin After Intraperitoneal Administration by Electrostatic Pressurized Intraperitoneal Aerosol Chemotherapy (ePIPAC): Systemic Pharmacokinetics of the CRC-PIPAC-II Trial2026 Annals of Surgical Oncology article Medicine Intraperitoneal and Appendiceal Malignancies Open access
Teun B M van den Heuvel, Paulien Rauwerdink, Emma C. Hulshof, Vincent C. J. van de Vlasakker, Dirk Jan A. R. Moes, Giulia Pluimakers, +9 more
2citations -
Systemic Pharmacokinetics of Oxaliplatin After Intraperitoneal Administration by Electrostatic Pressurized Intraperitoneal Aerosol Chemotherapy (ePIPAC) in Patients with Unresectable Colorectal Peritoneal Metastases in the CRC-PIPAC Trial2020 Annals of Surgical Oncology article Medicine Intraperitoneal and Appendiceal Malignancies cited by 2 patents
Robin J. Lurvink, Rudaba Tajzai, Koen P. B. Rovers, Emma C. E. Wassenaar, Dirk-Jan A. R. Moes, Giulia Pluimakers, +5 more
34citations -
1486MO The synovial and systemic pharmacokinetics and pharmacodynamics of intra-articular administration of the CSF1 receptor antibody AMB-05X in a phase II proof-of-concept trial in tenosynovial giant cell tumor2022 Annals of Oncology article Medicine Musculoskeletal synovial abnormalities and treatments Open access
Hans A. J. Gelderblom, M. Huang, Michiel A. J. van de Sande, Thomas J. Scharschmidt, O.A. Kostogryz, L. Alani, +2 more
3citations -
P-384 Quality of life and the systemic pharmacokinetics of oxaliplatin in patients with unresectable peritoneal metastases from colorectal cancer treated with repetitive electrostatic pressurized intraperitoneal aerosol chemotherapy (ePIPAC): The CRC-PIPAC trial2020 Annals of Oncology conference-abstract Medicine Intraperitoneal and Appendiceal Malignancies Open access
Robin J. Lurvink, Koen P. B. Rovers, Rudaba Tajzai, Emma C. E. Wassenaar, Floortje Mols, Dirk Jan A. R. Moes, +7 more
2citations -
A Phase II study of avenciguat, a novel soluble guanylate cyclase activator, in patients with systemic sclerosis: Study design and rationale of the VITALISScE™ study2024 Journal of Scleroderma and Related Disorders article Medicine Systemic Sclerosis and Related Diseases Open access
Dinesh Khanna, Jeska de Vries‐Bouwstra, Anna‐Maria Hoffmann‐Vold, Masataka Kuwana, Andrea Hsiu Ling Low, Susanna Proudman, +4 more
8citations -
Elenestinib, an Investigational, Next Generation KIT D816V Inhibitor, Reduces Mast Cell Burden, Improves Symptoms, and Has a Favorable Safety Profile in Patients with Indolent Systemic Mastocytosis: Analysis of the Harbor Trial
Tsewang Tashi, Olivier Hermine, Mariana Castells, Mar Guilarte, Vito Sabato, Marcus Maurer, +26 more
19citations -
Impact of mucositis on oral bioavailability and systemic exposure of ciprofloxacin Gram-negative infection prophylaxis in patients with haematological malignancies2022 Journal of Antimicrobial Chemotherapy article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Koen P. van Rhee, Suzanne L. de Vroom, Reinier M. van Hest, Paul D. van der Linden, Sanne H. Tonino, Eva B. D. Molendijk, +5 more
2citations -
Thymine as potential biomarker to predict 5-FU systemic exposure in patients with gastro-intestinal cancer: a prospective pharmacokinetic study (FUUT-trial)2025 Cancer Chemotherapy and Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Maarten A. Hanrath, Evi Banken, Sebastian A. H. van den Wildenberg, Daan van de Kerkhof, Dirk Jan A. R. Moes, Michèle Boisdron‐Celle, +7 more
1citations -
Administration of oxathridine, a first‐in‐class histamine‐3 receptor partial agonist in healthy male volunteers: Central nervous system depression and pseudo‐hallucinations2023 British Journal of Clinical Pharmacology article Immunology and Microbiology Mast cells and histamine Open access
Francis M. Dijkstra, Rob G. J. A. Zuiker, Jules A. A. C. Heuberger, Kawita M. S. Kanhai, Marieke de Kam, Thierry Duvauchelle, +8 more
1citations -
Distribution of acyclovir in central nervous system compartments: a porcine pharmacokinetic model2025 Antimicrobial Agents and Chemotherapy article Medicine Herpesvirus Infections and Treatments Open access
Theis Mariager, Jacob Holmen Terkelsen, Johan Mikkel Guldbæk, Jacob Toft Vestergaard, Mats Bue, Roland Nau, +4 more
2citations -
Effects of the phosphodiesterase 2 inhibitor BI 474121 on central nervous system cyclic guanosine monophosphate concentrations: Translational studies2024 British Journal of Clinical Pharmacology article Biochemistry, Genetics and Molecular Biology Phosphodiesterase function and regulation Open access
Sebastiaan J. W. van Kraaij, Rainer-Georg Goeldner, Holger Rosenbrock, Geert Jan Groeneveld, Philip H. C. Kremer, Jennifer Schaible, +2 more
2citations -
Pharmacokinetic/pharmacodynamic model-based optimization of temocillin dosing strategies for the treatment of systemic infections2024 Journal of Antimicrobial Chemotherapy article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Wisse van Os, Alina Karoline Nussbaumer-Pröll, Anh Duc Pham, Gert-Jan Wijnant, Perrin Ngougni Pokem, Françoise Van Bambeke, +2 more
3citations -
Plasma EC 90 multiples are drug, target site and species specific—A physiologically based pharmacokinetic modelling example of nirmatrelvir central nervous system distribution2026 British Journal of Pharmacology article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Daan W. van Valkengoed, Xuanlin Liu, Sean N. Avedissian, Courtney Vail Fletcher, Ashley N. Brown, Elizabeth C. M. de Lange, +1 more
0citations -
Physiologically Based Modelling Framework for Prediction of Pulmonary Pharmacokinetics of Antimicrobial Target Site Concentrations2022 Clinical Pharmacokinetics article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Linda B. S. Aulin, Sebastian Tommi Tandar, Torben van Zijp, Etienne van Ballegooie, Piet H. van der Graaf, Mohammed A. A. Saleh, +2 more
12citations -
Predictions of Bedaquiline Central Nervous System Exposure in Patients with Tuberculosis Meningitis Using Physiologically based Pharmacokinetic Modeling2024 Clinical Pharmacokinetics article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Krina Mehta, Pavel Balazki, Piet H. van der Graaf, Tingjie Guo, J. G. Coen van Hasselt
14citations -
Population Pharmacokinetics and Exposure‐Response Modeling of Daratumumab Subcutaneous Administration in Patients With Light‐Chain Amyloidosis2021 The Journal of Clinical Pharmacology article Biochemistry, Genetics and Molecular Biology Amyloidosis: Diagnosis, Treatment, Outcomes Open access
Man Luo, Peijuan Zhu, Ivo P. Nnane, Yuan Lu Xiong, Giampaolo Merlini, Raymond L. Comenzo, +9 more
10citations -
Pharmacokinetics of single and repeated oral doses of pregabalin oral solution formulation in cats2022 Journal of Veterinary Pharmacology and Therapeutics article Veterinary Veterinary Pharmacology and Anesthesia Open access
Terttu Lamminen, Anne Doedée, Minja Hyttilä‐Hopponen, Janne Kaskinoro
34citations