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Novel class of OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Anshu Bhattacharya, Yi-Lin Cheng, Marta Campos Alonso, Ahmad Reza Mehdipour, Gerbrand J. van der Heden van Noort, Huib Ovaa, +2 more
3citations -
Structural Basis of Substrate Selectivity and Catalysis in the Mycobacterial Long-Chain Acyl-CoA Carboxylase2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Lipid metabolism and biosynthesis Open access
Ajit Yadav, Nicole Rizzetto, Bogdan I. Florea, Sebastian Geibel
1citations -
CYP154C5 Regioselectivity in Steroid Hydroxylation Explored by Substrate and Protein Engineering2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access
Hein J. Wijma, Bastian Nicolai, Jhon Alexander Rodriguez Buitrago, Thomas Klünemann, Agustina Vila, Patrick Schrepfer, +3 more
0citations -
CYP154C5 Regioselectivity in Steroid Hydroxylation Explored by Substrate and Protein Engineering2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access
Hein J. Wijma, Bastian Nicolai, Jhon Alexander Rodriguez Buitrago, Thomas Klünemann, Agustina Vila, Patrick Schrepfer, +3 more
0citations -
KnowVolution of an efficient polyamidase through molecular dynamics simulations of incrementally docked oligomeric substrates2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access
Hendrik Puetz, Alexander-Maurice Illig, Mariia Vorobii, Christoph Janknecht, Francisca Contreras, Fabian Flemig, +1 more
1citations -
DNA-dependent binding of nargenicin to DnaE1 inhibits replication in Mycobacterium tuberculosis2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberculosis Research and Epidemiology Open access
Melissa Dalcina Chengalroyen, Mandy K. Mason, Alessandro Borsellini, R. Tassoni, Garth L. Abrahams, Sasha L. Lynch, +10 more
2citations -
Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferase2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access
Irene Georgiou, Colin Robinson, Sean N. O’Byrne, Alex Matsuda, Przemysław Grygier, Shamshad Ahmad, +17 more
1citations -
Transport mechanism of DgoT, a bacterial homolog of SLC17 organic anion transporters2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Drug Transport and Resistance Mechanisms Open access
Nataliia Dmitrieva, Samira Gholami, Claudia Alleva, Paolo Carloni, Mercedes Alfonso‐Prieto, Christoph Fahlke
2citations -
Macrocyclic Peptides as Allosteric Inhibitors of Nicotinamide N-Methyltransferase (NNMT)2020 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access cited by 3 patents
Matthijs J. van Haren, Yurui Zhang, Ned P. Buijs, Vito Thijssen, Davide Sartini, Monica Emanuelli, +2 more
3citations -
Macrocyclic Peptides as Allosteric Inhibitors of Nicotinamide N-Methyltransferase (NNMT)2020 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access
Matthijs J. van Haren, Yurui Zhang, Ned P. Buijs, Davide Sartini, Monica Emanuelli, Seino A. K. Jongkees, +1 more
0citations -
Functional and structural asymmetry suggest a unifying principle for catalysis in integral membrane-bound pyrophosphatases2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology ATP Synthase and ATPases Research Open access
Jannik Strauss, Craig Wilkinson, Keni Vidilaseris, Orquídea Ribeiro, Jianing Liu, James Hillier, +5 more
2citations -
The superior salinity tolerance of wheat cultivar Shanrong No. 3 cannot be attributed to elevated Ta-sro1 poly(ADP-ribose) polymerase activity2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Agricultural and Biological Sciences Plant Stress Responses and Tolerance Open access
Sarah Vogt, Karla L. H. Feijs, Raffaella De Masi, Ruth Lintermann, Bernhard Loll, Lennart Wirthmueller
1citations -
Molecular properties of RmlT, a wall teichoic acid rhamnosyltransferase that modulates virulence in Listeria monocytogenes2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Chemistry Carbohydrate Chemistry and Synthesis Open access
Ricardo Monteiro, Tatiana Cereija, Rita Pombinho, Sandra Sousa, João Henrique Morais-Cabral, Didier Cabanes
0citations -
SKOR1 mediates FER kinase-dependent invasive growth of breast cancer cells2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Mechanisms of cancer metastasis Open access
Lilian M. Sluimer, Esme Bullock, Max A. K. Rätze, Lotte N.F.L. Enserink, Celine Overbeeke, Marten Hornsveld, +3 more
1citations -
CellEKT: A robust chemical proteomics workflow to profile cellular target engagement of kinase inhibitors2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Chemistry Advanced Proteomics Techniques and Applications Open access
Joel Rüegger, Berend Gagestein, Antonius P. A. Janssen, Alexandra Valeanu, Alger Lazo Mori, Marielle van der Peet, +16 more
1citations -
Menaquinone-specific oxidation by M. tuberculosis cytochrome bd is redox regulated by the Q-loop disulfide bond2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Materials Science Enzyme Structure and Function Open access
Tijn T. van der Velden, Caspar Y. J. Waterham, Lars J. C. Jeuken
1citations -
Metagenomics Combined with Activity-Based Proteomics Point to Gut Bacterial Enzymes that Reactivate Mycophenolate2022 medRxiv preprint Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Joshua B. Simpson, Josh J. Sekela, Amanda L. Graboski, Valentina Borlandelli, Natalie K. Barker, Alicia A. Sorgen, +8 more
6citations -
Coronavirus hemagglutinin-esterase and spike proteins co-evolve for functional balance and optimal virion avidity2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Evolution and Genetic Dynamics Open access
Yifei Lang, Wentao Li, Zeshi Li, Danielle Koerhuis, Arthur C. S. van den Burg, Erik H. Rozemuller, +6 more
16citations -
A unique chaperoning mechanism in Class A JDPs recognizes and stabilizes mutant p532023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Heat shock proteins research Open access
Guy Zoltsman, Thi Lieu Dang, Miriam Kuchersky, Ofrah Faust, Micael S. Silva, Tal Ilani, +3 more
2citations