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A Patient‐Derived 3D Cyst Model of Polycystic Kidney Disease That Mimics Disease Development and Responds to Repurposing Candidates2025 Clinical and Translational Science article Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases Open access
Alina Meyer, Margarita Iljin, Hester Bange, Leo Price, Natalia Dyubankova, Gerard J. P. van Westen, +3 more
3citations -
A drug-repurposing screen of FDA- and EMA-approved drugs identifies two NF-κB inhibitors active against eumycetoma2025 Journal of Antimicrobial Chemotherapy article Medicine Actinomycetales infections and treatment Open access
Jingyi Ma, Bjorn R. van Doodewaerd, Bernhard Biersack, Annelies Verbon, Paul P. Geurink, Wendy W. J. van de Sande
2citations -
Knowledge Graphs and Explainable Artificial Intelligence (AI) for Drug Repurposing on Rare Diseases2026 Neurosymbolic Artificial Intelligence article Computer Science Computational Drug Discovery Methods Open access
Pablo Perdomo-Quinteiro, Katherine Wolstencroft, Marco Roos, Núria Queralt-Rosiñach
0citations -
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen2021 ACS Pharmacology & Translational Science article Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 8 patents
Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen, Francesca Esposito, Laura Vangeel, Bernhard Ellinger, +26 more
160citations -
Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease2021 Scientific Reports article Computer Science Computational Drug Discovery Methods Open access cited by 1 patent
Michael G. Sugiyama, Haotian Cui, Dar’ya S. Redka, Mehran Karimzadeh, Edurne Rujas, Hassaan Maan, +16 more
27citations -
A phenotype-driven data and drug repurposing strategy used to identify potential treatments targeting chondrocyte hypertrophy in osteoarthritis2025 Biomedicine & Pharmacotherapy article Medicine Osteoarthritis Treatment and Mechanisms Open access
Judith Veldman, Mauricio N. Ferrao Blanco, Nicole Kops, Wendy J. L. M. Koevoet, Eric M. Bindels, Gregory van Beek, +5 more
0citations -
SysQuan: Repurposing SILAC Mice for the Cost-Effective Absolute Quantitation of the Human Proteome2025 Molecular & Cellular Proteomics article Chemistry Advanced Proteomics Techniques and Applications Open access
Yassene Mohammed, Vincent R. Richard, M. Immanuel Reyes Madlangsakay, Ying Lao, Victor Spicer, Claudia Gaither, +4 more
4citations -
Repurposing Registries: Completeness of Real‐World Data for Regulatory and HTA Purposes in Three Cancer‐Focused Registries2026 Clinical Pharmacology & Therapeutics article Health Professions Electronic Health Records Systems Open access
Manon C. Wilpshaar, Doranne L. Hilarius, Luísa Prada, Ansgar Weltermann, Christine Leopold
1citations