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Transcriptome, metabolome and suppressor analysis reveal an essential role for the ubiquitin-proteasome system in seedling chloroplast development2022 BMC Plant Biology article Biochemistry, Genetics and Molecular Biology Photosynthetic Processes and Mechanisms Open access
Prabhavathi Talloji, Lilian Nehlin, Bruno Hüttel, Nikola Winter, Martin Černý, Hana Dufková, +9 more
3citations -
Harnessing PROTAC technology to combat stress hormone receptor activation2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Mahshid Gazorpak, Karina M. Hugentobler, Dominique Paul, Pierre‐Luc Germain, Miriam Kretschmer, Iryna Ivanova, +15 more
22citations -
The iRhom2/ADAM17 Axis Attenuates Bacterial Uptake by Phagocytes in a Cell Autonomous Manner2020 International Journal of Molecular Sciences article Immunology and Microbiology Phagocytosis and Immune Regulation Open access
Anke Seifert, Justyna Wozniak, Stefan Düsterhöft, Petr Kašpárek, Radislav Sedláček, Stephan Dreschers, +3 more
13citations -
Aro-Aat Reduces Z-AAT Protein in Pizz Patients and Leads to Improvements in Clinically Relevant Liver Biomarkers2021 Zeitschrift für Gastroenterologie conference-paper Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery
Pavel Strnad, Mattias Mandorfer, Gourab Choudhury, WJ Griffiths, Alice Margaret Turner, Christian Trautwein, +5 more
2citations -
Harnessing PROTAC technology to combat stress hormone receptor activation2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Mahshid Gazorpak, Karina M. Hugentobler, Dominique Paul, Pierre‐Luc Germain, Kei Matthis, Remo Rudolf, +11 more
0citations -
Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B2024 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Gerrit Wilms, Kevin Schofield, Shayna Maddern, Christopher Foley, Yeng Shaw, Breland E. Smith, +13 more
17citations -
Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell2024 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Yuqing Jia, Merve Oyken, Robbert Q. Kim, Rayman T.N. Tjokrodirijo, Arnoud H. de Ru, Antonius P. A. Janssen, +4 more
7citations -
A structural machine learning approach for rapid prediction of thermodynamically destabilizing tyrosine phosphorylations2025 Cell Reports Methods article Biochemistry, Genetics and Molecular Biology Machine Learning in Bioinformatics Open access
Jaie C. Woodard, Atena Malemir Chegini, Jian Tian, Rupa Bhowmick, Subramaniam Pennathur, Alireza Mashaghi, +2 more
3citations -
Rapid prediction of thermodynamically destabilizing tyrosine phosphorylations in cancers2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Machine Learning in Bioinformatics Open access
Jaie C. Woodard, Atena Malemir Chegini, Jian Tian, Rupa Bhowmick, Subramanium Pennathur, Alireza Mashaghi, +2 more
2citations -
Leveraging Targeted Protein Degradation for G Protein-Coupled Receptors: The Development of CCR2 Molecular Degraders2025 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Khaled Essa, Natalia V. Ortiz Zacarı́as, Sascha Röth, Bo‐Tao Xin, Sabine de Winter, Cas van der Horst, +10 more
2citations
15 results