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Phase 1 Safety and Immunogenicity Study of a Respiratory Syncytial Virus Vaccine With an Adenovirus 26 Vector Encoding Prefusion F (Ad26.RSV.preF) in Adults Aged ≥60 Years2020 The Journal of Infectious Diseases article Medicine Respiratory viral infections research cited by 9 patents
Kristi L. Williams, Arangassery Rosemary Bastian, Robert Feldman, Edmund V Ekoka Omoruyi, Els De Paepe, Jenny Hendriks, +6 more
111citations -
Efficacious human metapneumovirus vaccine based on AI-guided engineering of a closed prefusion trimer2024 Nature Communications article Medicine Respiratory viral infections research Open access cited by 1 patent
Mark J. G. Bakkers, Tina Ritschel, Machteld M. Tiemessen, Jacobus Dijkman, Angelo A. Zuffianò, Xiaodi Yu, +10 more
40citations -
RSV A2-Based Prefusion F Vaccine Candidates Induce RSV A and RSV B Cross Binding and Neutralizing Antibodies and Provide Protection against RSV A and RSV B Challenge in Preclinical Models
Freek Cox, Eiríkur Saeland, Anne Thoma, Ward van den Hoogen, Lisanne Tettero, Joke Drijver, +7 more
19citations -
Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains2020 Cell Reports article Immunology and Microbiology HIV Research and Treatment Open access cited by 2 patents
Reda Rawi, Lucy Rutten, Yen‐Ting Lai, Adam S. Olia, Sven Blokland, Jarek Juraszek, +9 more
46citations -
A foldon-free prefusion F trimer vaccine for respiratory syncytial virus to reduce off-target immune responses2024 Nature Microbiology article Medicine Respiratory viral infections research Open access cited by 1 patent
Mark J. G. Bakkers, Freek Cox, Annemart Koornneef, Xiaodi Yu, Daan van Overveld, Lam Le, +9 more
26citations -
Structure-Based Design of Prefusion-Stabilized Filovirus Glycoprotein Trimers2020 Cell Reports article Medicine Viral Infections and Outbreaks Research Open access cited by 15 patents
Lucy Rutten, Morgan S. A. Gilman, Sven Blokland, Jarek Juraszek, Jason S. McLellan, Johannes P. M. Langedijk
80citations -
Ad26-vector based COVID-19 vaccine encoding a prefusion stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 21 patents
Rinke Bos, Lucy Rutten, Joan E. M. van der Lubbe, Mark J. G. Bakkers, Gijs Hardenberg, Frank Wegmann, +18 more
45citations -
Structural basis for potent neutralization of human respirovirus type 3 by protective single-domain camelid antibodies2024 Nature Communications article Medicine Monoclonal and Polyclonal Antibodies Research Open access
Nicole V. Johnson, Revina C. van Scherpenzeel, Mark J. G. Bakkers, Ajit R. Ramamohan, Daan van Overveld, Lam Le, +3 more
5citations -
Improved RSV preF protein vaccine quality and stability by elucidation of supercooling-induced aggregation phenomena2024 European Journal of Pharmaceutics and Biopharmaceutics article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access
Max Beugeling, Wallace A. Kaserer, A.J.P. van Heugten, Martinus A.H. Capelle
0citations -
Impact of SARS-CoV-2 spike stability and RBD exposure on antigenicity and immunogenicity2024 Scientific Reports article Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 2 patents
Lucy Rutten, Maarten Swart, Annemart Koornneef, Pascale Bouchier, Sven Blokland, Ava Sadi, +16 more
16citations -
Safety and Immunogenicity of the Ad26.RSV.preF Investigational Vaccine Coadministered With an Influenza Vaccine in Older Adults2020 The Journal of Infectious Diseases article Medicine Respiratory viral infections research Open access
JERALD C. SADOFF, Els De Paepe, Wouter Haazen, Edmund V Ekoka Omoruyi, Arangassery Rosemary Bastian, Christy A. Comeaux, +4 more
52citations -
Safety, Immunogenicity, and Regimen Selection of Ad26.RSV.preF–Based Vaccine Combinations: A Randomized, Double-blind, Placebo-Controlled, Phase 1/2a Study2023 The Journal of Infectious Diseases article Medicine Respiratory viral infections research Open access
Christy A. Comeaux, Stephan Bart, Arangassery Rosemary Bastian, V. G. Klyashtorny, Els De Paepe, Edmund V Ekoka Omoruyi, +5 more
21citations -
Combination Ad26.RSV.preF/preF protein vaccine induces superior protective immunity compared with individual vaccine components in preclinical models2023 npj Vaccines article Medicine Respiratory viral infections research Open access cited by 1 patent
Eiríkur Saeland, Leslie van der Fits, Renske Bolder, Marjolein Heemskerk-van der Meer, Joke Drijver, Yolinda van Polanen, +9 more
18citations -
CoPoP liposomes displaying stabilized clade C HIV-1 Env elicit tier 2 multiclade neutralization in rabbits2024 Nature Communications article Immunology and Microbiology HIV Research and Treatment Open access
Annemart Koornneef, Kanika Vanshylla, Gijs Hardenberg, Lucy Rutten, Nika M. Strokappe, Jeroen T. B. M. Tolboom, +13 more
9citations -
Combination Ad26.RSV.preF/RSV preF protein vaccine induces superior humoral, cellular, and protective immunity compared with individual vaccine components in preclinical models2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Respiratory viral infections research Open access
Eiríkur Saeland, Leslie van der Fits, Renske Bolder, Marjolein Heemskerk-van der Meer, Joke Drijver, Yolinda van Polanen, +9 more
1citations
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