Papers matching “predictive toxicity models” 21
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Validation of an MPS based intestinal cell culture model for the evaluation of drug-induced toxicity2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Engineering 3D Printing in Biomedical Research Open access
Stefanie Hoffmann, Philip Hewitt, Isabel Koscielski, Dorota Kurek, Wouter Strijker, Kinga Kosim
0citations -
Scalable proxiloids enable human-relevant assessment of kidney proximal tubule toxicity2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Acute Kidney Injury Research Open access
Sam Biermans, Dara N. van Heugten, M. Cristina Avramut, Roos-Sanne F. Verkerk, Rianne Y. van Nieuwland, Roan H van Scheppingen, +6 more
0citations -
Assessing chemical toxicity across Eukaryota using multimodal transformers2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Environmental Science Environmental Toxicology and Ecotoxicology Open access
Styrbjörn Käll, Mikael B. Gustavsson, Patrik Svedberg, Mercedes Dalman, Jens Henriksson, Thomas Backhaus, +1 more
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Towards Bayesian-based quantitative adverse outcome pathways using in vitro data from open literature and continuous variables: a case example for liver fibrosis2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Robin Durník, Tereza Juchelková, Helge Hecht, Levi M. T. Winkelman, Joost B. Beltman, Xavier Coumoul, +4 more
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Integration of In Vitro and In Silico Approaches Enables Prediction of Drug-Induced Liver Injury2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
René Geci, Ahenk Zeynep Sayin, Stephan Schaller, Lars Kuepfer
0citations -
AI-aided chronic mixture risk assessment along a small European river reveals multiple sites at risk and pharmaceuticals being the main risk drivers2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Environmental Science Environmental Toxicology and Ecotoxicology Open access
Fabian G. Weichert, Pedro A. Inostroza, Jörg Ahlheim, Thomas Backhaus, Werner Brack, Mario Brauns, +4 more
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A simplified co-culture reveals altered cardiotoxic responses to doxorubicin in hPSC-derived cardiomyocytes in the presence of endothelial cells2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Chemotherapy-induced cardiotoxicity and mitigation Open access
Marcella Brescia, Andrea Chatrian, Paul Keselman, James Gallant, Elsa Sorman Paulsson, Mervyn P.H. Mol, +10 more
1citations -
MultiGML: Multimodal Graph Machine Learning for Prediction of Adverse Drug Events2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access
Sophia Krix, Lauren Nicole DeLong, Sumit Madan, Daniel Domingo‐Fernándéz, Ashar Ahmad, Sheraz Gul, +2 more
3citations -
Keep looking at the negative side: improved detection of drug-induced liver injury with non-hepatotoxicant data oversampling2025 ChemRxiv preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Olivier J. M. Béquignon, Steven Wink, Steven W. Hiemstra, J. E. Fokkelman-Klip, Wouter den Hollander, Giulia Callegaro, +2 more
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Keep looking at the negative side: improved detection of drug-induced liver injury with non-hepatotoxicant data oversampling2025 ChemRxiv preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Olivier J. M. Béquignon, Steven Wink, Steven W. Hiemstra, J. E. Fokkelman-Klip, Wouter den Hollander, Giulia Callegaro, +2 more
0citations -
Systematic Evaluation of High-Throughput PBK Modelling Strategies for the Prediction of Intravenous and Oral Pharmacokinetics in Humans2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access
René Geci, Domenico Gadaleta, Marina García de Lomana, Rita Ortega-Vallbona, Erika Colombo, Eva Serrano‐Candelas, +3 more
0citations -
Unraveling interindividual differences and functional consequences of gut microbial metabolism of immunosuppressants2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Maral Baghai Arassi, Nicolai Karcher, Eleonora Mastrorilli, Matthias Groß, Amber Brauer-Nikonow, David Czock, +3 more
6citations
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