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Magnitude of Off-Target Allo-HLA Reactivity by Third-Party Donor-Derived Virus-Specific T Cells Is Dictated by HLA-Restriction2021 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access cited by 1 patent
Wesley Huisman, Didier A.T. Leboux, Lieve E. van der Maarel, Lois Hageman, Derk Amsen, J.H. Frederik Falkenburg, +1 more
19citations -
Determining off-target effects of splice-switching antisense oligonucleotides using short read RNAseq in neuronally differentiated human induced pluripotent stem cells2025 Human Molecular Genetics article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Elsa C. Kuijper, Linda van der Graaf, Barry A. Pepers, Mariana Guimarães Ramos, Sylvia Korhorn, Lodewijk J.A. Toonen, +5 more
5citations -
Preclinical Assessment of ADAM9-Responsive Mesoporous Silica Nanoparticles for the Treatment of Pancreatic Cancer2023 International Journal of Molecular Sciences article Materials Science Nanoparticle-Based Drug Delivery Open access
Etienne J. Slapak, Mouad el Mandili, Marieke S. ten Brink, Alexander Kros, Maarten F. Bijlsma, C. Arnold Spek
6citations -
Transformative Materials for Interfacial Drug Delivery2023 Advanced Healthcare Materials article Pharmacology, Toxicology and Pharmaceutics Advanced Drug Delivery Systems Open access
Prachi Bharat Desai, Anshuman Dasgupta, Alexandros Marios Sofias, Quim Peña, Robert Göstl, Ioana Slabu, +10 more
9citations -
CD229 CAR T cells eliminate multiple myeloma and tumor propagating cells without fratricide2020 Nature Communications article Medicine CAR-T cell therapy research Open access cited by 4 patents
Sabarinath Venniyil Radhakrishnan, Tim Luetkens, Sandra D. Scherer, Patricia M. Davis, Erica R. Vander Mause, Michael Olson, +8 more
79citations -
A broad kinase inhibitor library live cell imaging screen using liver, kidney and cardiac hiPSC-ICAM1-eGFP reporter lineages identifies liabilities for TNFα pathway modulation2025 Archives of Toxicology article Computer Science Computational Drug Discovery Methods Open access
Matthijs Vlasveld, Linda van den Berk, Janet Piñero, Palle Steen Helmke, Gerhard Franz Ecker, Rob Van Rossom, +5 more
1citations -
DrugEx v2: de novo design of drug molecules by Pareto-based multi-objective reinforcement learning in polypharmacology2021 Journal of Cheminformatics article Computer Science Computational Drug Discovery Methods Open access cited by 1 patent
Xuhan Liu, Kai Ye, Herman van Vlijmen, Michael Emmerich, Adriaan P. IJzerman, Gerard J. P. van Westen
118citations -
The role of zongertinib, a highly selective tyrosine kinase inhibitor, in targeting HER2 -mutant NSCLC: a bench-to-bedside review2026 Expert Review of Anticancer Therapy article Medicine Lung Cancer Treatments and Mutations Open access
John Victor Heymach, Sanjay Popat, Egbert Frederik Smit, Petros Christopoulos, David Planchard, T. Yoshida, +3 more
2citations -
Identifying Novel Inhibitors for Hepatic Organic Anion Transporting Polypeptides by Machine Learning-Based Virtual Screening2022 Journal of Chemical Information and Modeling article Computer Science Computational Drug Discovery Methods Open access
Alzbeta Tuerkova, Brandon J. Bongers, Ulf Norinder, Orsolya Ungvári, Virág Székely, Andrey Tarnovskiy, +4 more
24citations
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