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Magnitude of Off-Target Allo-HLA Reactivity by Third-Party Donor-Derived Virus-Specific T Cells Is Dictated by HLA-Restriction2021 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access cited by 1 patent
Wesley Huisman, Didier A.T. Leboux, Lieve E. van der Maarel, Lois Hageman, Derk Amsen, J.H. Frederik Falkenburg, +1 more
19citations -
Determining off-target effects of splice-switching antisense oligonucleotides using short read RNAseq in neuronally differentiated human induced pluripotent stem cells2025 Human Molecular Genetics article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Elsa C. Kuijper, Linda van der Graaf, Barry A. Pepers, Mariana Guimarães Ramos, Sylvia Korhorn, Lodewijk J.A. Toonen, +5 more
5citations -
Determining off-target effects of splice-switching antisense oligonucleotides using short read RNAseq in neuronally differentiated human induced pluripotent stem cells2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Elsa C. Kuijper, Linda M. van der Graaf, Barry A. Pepers, Mariana Guimarães Ramos, Sylvia Korhorn, Davy Cats, +4 more
1citations -
Integrated risk assessment reveals low biological activity of RNA-based crop protection formulations across plant and non-target systems2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Insect Resistance and Genetics Open access
Moritz Dobrowitsch, Sandra Friedrich, Jonas Noetzold, Maria Bender, Benjamin Moorlach, Katharina Eickelpasch, +8 more
0citations -
148 Primary or iPSC-derived cell-based cytotoxicity assays to assess potential safety risks of engineered T cell therapies in vitro2021 Regular and Young Investigator Award Abstracts conference-abstract Medicine CAR-T cell therapy research Open access
Sophie Vermond, Monique Hazenoot, Rene J. McLaughlin, Sabrina de Munnik, Marco Guadagnoli, Gemma Moiset, +2 more
0citations -
Preclinical Assessment of ADAM9-Responsive Mesoporous Silica Nanoparticles for the Treatment of Pancreatic Cancer2023 International Journal of Molecular Sciences article Materials Science Nanoparticle-Based Drug Delivery Open access
Etienne J. Slapak, Mouad el Mandili, Marieke S. ten Brink, Alexander Kros, Maarten F. Bijlsma, C. Arnold Spek
6citations -
Transformative Materials for Interfacial Drug Delivery2023 Advanced Healthcare Materials article Pharmacology, Toxicology and Pharmaceutics Advanced Drug Delivery Systems Open access
Prachi Bharat Desai, Anshuman Dasgupta, Alexandros Marios Sofias, Quim Peña, Robert Göstl, Ioana Slabu, +10 more
9citations -
CD229 CAR T cells eliminate multiple myeloma and tumor propagating cells without fratricide2020 Nature Communications article Medicine CAR-T cell therapy research Open access cited by 4 patents
Sabarinath Venniyil Radhakrishnan, Tim Luetkens, Sandra D. Scherer, Patricia M. Davis, Erica R. Vander Mause, Michael Olson, +8 more
79citations -
A broad kinase inhibitor library live cell imaging screen using liver, kidney and cardiac hiPSC-ICAM1-eGFP reporter lineages identifies liabilities for TNFα pathway modulation2025 Archives of Toxicology article Computer Science Computational Drug Discovery Methods Open access
Matthijs Vlasveld, Linda van den Berk, Janet Piñero, Palle Steen Helmke, Gerhard Franz Ecker, Rob Van Rossom, +5 more
1citations -
RIPK1 and MLKL in hepatocytes do not mediate Concanavalin A (ConA)-mediated liver toxicity2020 Zeitschrift für Gastroenterologie conference-paper Biochemistry, Genetics and Molecular Biology Cell death mechanisms and regulation
AT Schneider, Christiane Koppe, SH Loosen, JN Kather, Christian Trautwein, Mihael Vucur, +1 more
0citations