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Rationale and design of the OPTIMIZE trial: OPen label multicenter randomized trial comparing standard IMmunosuppression with tacrolimus and mycophenolate mofetil with a low exposure tacrolimus regimen In combination with everolimus in de novo renal transplantation in Elderly patients
Silke E. de Boer, Jan‐Stephan Sanders, Fréderike J. Bemelman, Michiel G.H. Betjes, Johannes G. M. Burgerhof, Luuk B. Hilbrands, +7 more
16citations -
Assessing the efficacy and safety of mycophenolate mofetil versus azathioprine in patients with autoimmune hepatitis (CAMARO trial): study protocol for a randomised controlled trial
Romée J.A.L.M. Snijders, Anna Stoelinga, Tom J.G. Gevers, Simon Pape, Maaike Biewenga, Robert C. Verdonk, +20 more
12citations -
Methotrexate Versus Mycophenolate Mofetil Prophylaxis in Allogeneic Hematopoietic Cell Transplantation for Chronic Myeloid Malignancies: A Retrospective Analysis on Behalf of the Chronic Malignancies Working Party of the EBMT2024 American Journal of Hematology article Medicine Hematopoietic Stem Cell Transplantation Open access
Thomas Luft, Luuk A. Gras, Linda Köster, Nicolaus Martin Kröger, Thomas A. Schroeder, Uwe Platzbecker, +19 more
3citations -
Characterization of the Immune Response after Oral Cholera Vaccination ( OCV ) and Effects of Mycophenolate Mofetil on Priming of this Immune Response—A Randomized, Placebo‐Controlled Trial2026 Clinical Pharmacology & Therapeutics article Biochemistry, Genetics and Molecular Biology Vibrio bacteria research studies Open access
Boukje C. Eveleens Maarse, Aliede E. in ‘t Veld, Hendrika W. Grievink, Manon A. A. Jansen, Matthijs Moerland
0citations -
Assessing the efficacy and safety of mycophenolate mofetil versus azathioprine in patients with autoimmune hepatitis (CAMARO trial): study protocol for a randomised controlled trial
Romée J.A.L.M. Snijders, Anna Stoelinga, Tom J.G. Gevers, Simon Pape, Maaike Biewenga, Robert C. Verdonk, +20 more
1citations -
Replacing Mycophenolate Mofetil by Everolimus in Kidney Transplant Recipients to Increase Vaccine Immunogenicity: Results of a Randomized Controlled Trial2025 Clinical Infectious Diseases article Medicine Renal Transplantation Outcomes and Treatments Open access
A. Lianne Messchendorp, Luca M. Zaeck, Pim Bouwmans, Dennis A. J. van den Broek, Sophie C. Frölke, Daryl Geers, +37 more
5citations -
Metagenomics combined with activity-based proteomics point to gut bacterial enzymes that reactivate mycophenolate2022 Gut Microbes article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Joshua B. Simpson, Josh J. Sekela, Amanda L. Graboski, Valentina Borlandelli, Marissa M. Bivins, Natalie K. Barker, +9 more
43citations -
Metagenomics Combined with Activity-Based Proteomics Point to Gut Bacterial Enzymes that Reactivate Mycophenolate2022 medRxiv preprint Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Joshua B. Simpson, Josh J. Sekela, Amanda L. Graboski, Valentina Borlandelli, Natalie K. Barker, Alicia A. Sorgen, +8 more
6citations -
Tacrolimus versus mycophenolate for AutoImmune hepatitis patients with incompLete response On first-line therapy (TAILOR study): a study protocol for a phase III, open-label, multicentre, randomised controlled trial
Anna Stoelinga, Maarten E. Tushuizen, Wilbert B. van den Hout, Mar D. M. Rodriguez Girondo, Elsemieke S. de Vries, Amar D. Levens, +15 more
11citations -
Tacrolimus versus mycophenolate for autoimmune hepatitis patients with incomplete response on first line therapy (TAILOR study): a study protocol for a phase III, open-label, multicentre, randomised controlled trial
Anna Stoelinga, Maarten E. Tushuizen, Wilbert B. van den Hout, Mar D. M. Rodriguez Girondo, Elsemieke S. de Vries, Amar D. Levens, +11 more
1citations -
Randomized Clinical Trial in Older Adult Kidney Transplant Recipients Comparing Everolimus and Reduced-Dose Tacrolimus with Mycophenolate and Tacrolimus Immunosuppression: The OPTIMIZE Study2025 Journal of the American Society of Nephrology article Medicine Renal Transplantation Outcomes and Treatments
Stefan P. Berger, Silke E. de Boer, Jip Jonker, Fréderike J. Bemelman, Michiel G.H. Betjes, Aiko P. J. de Vries, +7 more
0citations -
Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology2021 Therapeutic Drug Monitoring article Medicine Renal Transplantation Outcomes and Treatments Open access
Stein Bergan, Merçè Brunet, Dennis Alexander Hesselink, Kamisha L. Johnson‐Davis, Paweł K. Kunicki, Pierre P. Marquet, +30 more
208citations -
Information preferences about treatment options in diffuse cutaneous systemic sclerosis: A Delphi consensus study2021 Journal of Scleroderma and Related Disorders article Medicine Systemic Sclerosis and Related Diseases Open access
Julia Spierings, Hilde H. Nienhuis, Eva van Lieshout, Jacob M. van Laar, Arwen H. Pieterse
2citations -
Voclosporin: a novel calcineurin inhibitor with no impact on mycophenolic acid levels in patients with SLE2021 Nephrology Dialysis Transplantation article Medicine Systemic Lupus Erythematosus Research Open access cited by 1 patent
Teun van Gelder, Robert B. Huizinga, Laura Lisk, Neil Solomons
25citations -
Increased levels of a mycophenolic acid metabolite in patients with kidney failure negatively affect cardiomyocyte health2024 Frontiers in Cardiovascular Medicine article Medicine Dialysis and Renal Disease Management Open access
Eva Harlacher, Corinna Schulte, Sonja Vondenhoff, Philippe Schmitt‐Kopplin, Philippe Diederich, Christian Hemmers, +13 more
3citations -
Two-Year, Randomized, Controlled Trial of Belimumab in Lupus Nephritis2020 New England Journal of Medicine article Medicine Systemic Lupus Erythematosus Research Open access cited by 12 patents
Richard Alan Furie, Brad H. Rovin, Frédéric Houssiau, Ana Malvar, Y K Onno Teng, Gabriel N. Contreras, +11 more
1,041citations