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Exposure to complex mixtures of urban sediments containing Tyre and Road Wear Particles (TRWPs) increases the germ-line mutation rate in Chironomus riparius2025 Aquatic Toxicology article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Markus Schmitz, Volker Linnemann, Martin Krayer Von Krauss, Henner Hollert, Markus Pfenninger
11citations -
Clinical sequencing identifies potential actionable alterations in a high rate of urachal and primary bladder adenocarcinomas2023 Cancer Medicine article Biochemistry, Genetics and Molecular Biology Cancer Genomics and Diagnostics Open access
Melinda Váradi, Nikolett T. Nagy, Henning Reis, Boris Alexander Hadaschik, Christian Niedworok, Orsolya Módos, +20 more
18citations -
Human induced pluripotent stem cells display a similar mutation burden as embryonic pluripotent cells in vivo2022 iScience article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Karlijn Hasaart, Freek Manders, Joske Ubels, Mark Verheul, Markus J. van Roosmalen, Niels M. Groenen, +4 more
9citations -
Analytical and Clinical Validation of the Oncomine Dx Target Test to Assess HER2 Mutation Status in Tumor Tissue Samples From Patients With Non–Small Cell Lung Cancer Treated With Trastuzumab Deruxtecan in the DESTINY-Lung01 and DESTINY-Lung02 Studies2024 Archives of Pathology & Laboratory Medicine article Medicine Lung Cancer Treatments and Mutations Open access
Zhenhao Qi, Wenqin Feng, Maha Karnoub, Kaline Pereira, Ryota Shiga, Egbert Frederik Smit, +5 more
5citations -
IMPemBra: a phase 2 study comparing pembrolizumab with intermittent/short-term dual MAPK pathway inhibition plus pembrolizumab in patients with melanoma harboring the BRAFV600 mutation2023 Journal for ImmunoTherapy of Cancer article Biochemistry, Genetics and Molecular Biology Melanoma and MAPK Pathways Open access
Elisa A. Rozeman, Judith M. Versluis, Karolina Sikorska, Esmée P. Hoefsmit, Petros Dimitriadis, Disha Rao, +15 more
17citations -
Correcting a PLCζ Mutation in the Human Germ Line to Overcome Hereditary Infertility2022 Fertility & Reproduction article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Bieke Bekaert, Annekatrien Boel, Lisa De Witte, Mina Popovic, Panagiotis Stamatiadis, Gwenny Cosemans, +7 more
0citations -
Trastuzumab-Emtansine and Osimertinib Combination Therapy to Target HER2 Bypass Track Resistance in EGFR Mutation-Positive NSCLC2023 JTO Clinical and Research Reports article Medicine Lung Cancer Treatments and Mutations Open access
M. Jebbink, Adrianus Johannes De Langen, Kim Monkhorst, Mirjam C. Boelens, Daan van den Broek, Vincent van der Noort, +8 more
24citations -
Nationwide evaluation of mutation-tailored anti-EGFR therapy selection in patients with colorectal cancer in daily clinical practice2021 Journal of Clinical Pathology article Medicine Colorectal Cancer Treatments and Studies Open access
Elisabeth M. P. Steeghs, Geraldine R. Vink, Marloes A.G. Elferink, Quirinus J.M. Voorham, Hans A. J. Gelderblom, Irıs D. Nagtegaal, +2 more
0citations -
Mutation accumulation opposes polymorphism: supergenes and the curious case of balanced lethals2022 Philosophical Transactions of the Royal Society B Biological Sciences article Biochemistry, Genetics and Molecular Biology Evolution and Genetic Dynamics Open access
Emma L. Berdan, Alexandre Blanckaert, Roger Kenneth Butlin, Thomas Flatt, Tanja Slotte, Ben Wielstra
31citations -
The G132S Mutation Enhances the Resistance of Mycobacterium tuberculosis β-Lactamase against Sulbactam2021 Biochemistry article Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access
Ilona van Alen, Aleksandra Chikunova, Adil Safeer, Misbha Ud Din Ahmad, Anastassis Perrakis, Marcellus Ubbink
21citations -
Sex‐related differences in aging rate are associated with sex chromosome system in amphibians2021 Evolution article Biochemistry, Genetics and Molecular Biology Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities Open access
Hugo Cayuela, Jean‐François Lemaître, Jean‐Paul Léna, Victor Ronget, Íñigo Martínez-Solano, Erin Muths, +42 more
21citations -
Clonal haematopoiesis of indeterminate potential and impaired kidney function—A Danish general population study with 11 years follow‐up2022 European Journal Of Haematology article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Morten Kranker Larsen, Vibe Skov, Lasse Kjær, Natascha A. Møller‐Palacino, Rasmus Kristoffer Pedersen, Morten Andersen, +14 more
18citations -
Quantitative modeling of tumor dynamics and development of drug resistance in non‐small cell lung cancer patients treated with erlotinib2024 CPT Pharmacometrics & Systems Pharmacology article Medicine Lung Cancer Treatments and Mutations Open access
Anyue Yin, G. Veerman, J. G. Coen van Hasselt, Christi M. J. Steendam, Hendrikus Jan Dubbink, Henk‐Jan Guchelaar, +4 more
6citations -
Large-scale pedigree analysis highlights rapidly mutating Y-chromosomal short tandem repeats for differentiating patrilineal relatives and predicting their degrees of consanguinity2022 Human Genetics article Biochemistry, Genetics and Molecular Biology Forensic and Genetic Research Open access
Arwin Ralf, Diego Montiel González, Dion Zandstra, Bram van Wersch, Nefeli Kousouri, Peter de Knijff, +4 more
23citations