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Diet and exercise reduce pre-existing NASH and fibrosis and have additional beneficial effects on the vasculature, adipose tissue and skeletal muscle via organ-crosstalk
Anita M. van den Hoek, Jelle C. B. C. de Jong, Nicole Worms, Anita van Nieuwkoop, Marijke Voskuilen, Aswin L. Menke, +4 more
53citations -
Diffusion‐tensor magnetic resonance imaging captures increased skeletal muscle fibre diameters in Becker muscular dystrophy2023 Journal of Cachexia Sarcopenia and Muscle article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Donnie Cameron, Tooba Abbassi‐Daloii, Laura G.M. Heezen, Nienke M. van de Velde, Zaïda Koeks, Thom T. J. Veeger, +10 more
23citations -
The vitamin B 3 analogue nicotinamide riboside has only very minor effects on reducing muscle damage in mdx mice2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Tiberiu Loredan Stan, Ingrid E.C. Verhaart, Annemieke M Aartsma-Rus
0citations -
Simvastatin Treatment Does Not Ameliorate Muscle Pathophysiology in a Mouse Model for Duchenne Muscular Dystrophy2020 Journal of Neuromuscular Diseases article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Ingrid E.C. Verhaart, Ornella Cappellari, Christa L. Tanganyika-de Winter, Jaap J. Plomp, Sofia Nnorom, Kim E. Wells, +3 more
17citations -
Efficient Downregulation of Alk4 in Skeletal Muscle After Systemic Treatment with Conjugated siRNAs in a Mouse Model for Duchenne Muscular Dystrophy2022 Nucleic Acid Therapeutics article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Sarah Engelbeen, Svetlana Pasteuning-Vuhman, Rubina Giare Parmar, Klaus Charissé, Laura Sepp‐Lorenzino, Muthiah A. Manoharan, +2 more
14citations -
Integrin α1β1 Promotes Interstitial Fibrosis and Cyst Growth in a Mouse Model of Polycystic Kidney Disease2025 Journal of the American Society of Nephrology article Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases Open access
Céline Grenier, I‐Hsuan Lin, Dorien J.M. Peters, Ambra Pozzi, Rachel Lennon, Richard William Naylor
3citations -
Integrin alpha1 beta1 promotes interstitial fibrosis in a mouse model of polycystic kidney disease2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases Open access
I‐Hsuan Lin, Dorien J.M. Peters, Ambra Pozzi, Rachel Lennon, Richard William Naylor
2citations -
Antisense oligonucleotide-mediated terminal intron retention of endoglin: A potential strategy to inhibit renal interstitial fibrosis2024 Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease article Medicine Chronic Kidney Disease and Diabetes Open access
Tessa Gerrits, Kyra L. Dijkstra, Jan Anthonie Bruijn, Marion Scharpfenecker, Roel Bijkerk, Hans J. Baelde
4citations -
Association of endothelial to mesenchymal transition and cellular senescence with fibrosis in skin biopsies of systemic sclerosis patients: a cross-sectional study2022 Clinical and Experimental Rheumatology article Medicine Systemic Sclerosis and Related Diseases Open access
Yu‐Hsiang Chiu, Julia Spierings, Jacob M. van Laar, Jeska Kirsten De Vries-Bouwstra, Marijke R. van Dijk, Roel Goldschmeding
15citations -
Towards Bayesian-based quantitative adverse outcome pathways using in vitro data from open literature and continuous variables: a case example for liver fibrosis2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Robin Durník, Tereza Juchelková, Helge Hecht, Levi M. T. Winkelman, Joost B. Beltman, Xavier Coumoul, +4 more
0citations -
Towards Bayesian-based quantitative adverse outcome pathways using in vitro data from open literature and continuous variables: a case example for liver fibrosis2026 Toxicological Sciences article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Robin Durník, Tereza Juchelková, Helge Hecht, Levi M. T. Winkelman, Joost B. Beltman, Xavier Coumoul, +4 more
0citations -
P260 The vitamin B3 analogue nicotinamide riboside has only very minor effects on reducing muscle damage in mdx mice2023 Neuromuscular Disorders conference-abstract Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders
Tiberiu Loredan Stan, D. vd Vijver, Ingrid E.C. Verhaart, Annemieke M Aartsma-Rus
1citations -
Compartment-specific remodeling of skeletal muscle in Duchenne muscular dystrophy2026 Research Square preprint Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Clara Martínez Mir, Paola Pisterzi, Isabel de Poorter, Jamilla Beek, Anna Alemany, Fanny Sage, +1 more
0citations -
Response to: Low molecular weight guluronate: A potential therapies for inspiratory muscle dysfunction and restrictive lung function impairment in congenital heart disease by Guiyuan He, Ruiting Zhou, Tingyuan Huang, Fanjun Zeng
Jens Spießhoefer, Binaya Regmi, Stefan Orwat, Hans‐Joachim Kabitz, Alberto Giannoni, Michael Dreher, +2 more
0citations -
Myofibre-specific knockout of TGF-β type I receptors triggers muscle hypertrophy and promotes contraction and oxidative metabolism2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders
Andi Shi, Michèle MG Hillege, Carla Offringa, Gang Wu, Tymour Forouzanfar, Willem M.H. Hoogaars, +2 more
1citations