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A proteomic map of B cell activation and its shaping by mTORC1, MYC and iron2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Olivia James, Linda V. Sinclair, Nadejda Lefter, Andrew J.M. Howden
1citations -
AP-1 complex activation is a conserved signature of immune system aging and a potential regulator of inflammaging in human and mice2021 Research Square preprint Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Emin Onur Karakaslar, Muneer G. Hasham, Neerja Katiyar, Ahrim Youn, Siddhartha Sharma, Cheng‐Han Chung, +4 more
0citations -
Cross-species analyses reveal RORγt-expressing dendritic cells are a lineage of antigen presenting cells conserved across tissues2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immunotherapy and Immune Responses Open access cited by 3 patents
Hamsa Narasimhan, Maria Lucia Richter, Ramin Shakiba, Nikos E. Papaioannou, Christina Stehle, Isabel Ulmert, +12 more
5citations -
Glutamine-driven mTORC1 activity enforces glycolytic bias, hyperactivation and aberrant proliferation in T cells in chronic B-cell leukemia2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism
Nienke B. Goedhart, Elena Camerini, Gaspard Cretenet, Anita E. Grootemaat, Kirill Vlaskov, Chaja Feige Jacobs, +10 more
0citations -
Myeloid reprogramming by JAK inhibition enhances checkpoint blockade therapy2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immune cells in cancer Open access
Jaroslav Žák, Isaraphorn Pratumchai, Brett S. Marro, Kristi Marquardt, Reza Beheshti Zavareh, Luke L. Lairson, +4 more
6citations -
WALDO: community-Wide Annotation of γδ Lymphocytes in single-cell Data, Openly benchmarked2026 Zenodo (CERN European Organization for Nuclear Research) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Farid Keramati, Moosa Rezwani, Likai Tan, David Hamilton, Zheng Song, Tao Yang, +10 more
0citations -
Adaptive subsets limit the anti-tumoral NK-cell activity in Hepatocellular Carcinoma2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immune Cell Function and Interaction Open access
Charlotte Rennert, Catrin Tauber, Pia Fehrenbach, Kathrin Heim, Dominik Bettinger, Oezlem Sogukpinar, +10 more
3citations -
The helminth TGF-β mimic TGM4 is a modular ligand that binds CD44, CD49d and TGF-β receptors to preferentially target myeloid cells2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Parasites and Host Interactions Open access
Shashi Prakash Singh, Danielle J. Smyth, Kyle T. Cunningham, Ananya Mukundan, Chang‐Hyeock Byeon, Cynthia S. Hinck, +12 more
1citations -
TGM6, a helminth secretory product, mimics TGF-β binding to TβRII to antagonize TGF-β signaling in fibroblasts2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Stephen E. White, Tristin A. Schwartze, Ananya Mukundan, Christina Schoenherr, Shashi Prakash Singh, Maarten van Dinther, +9 more
5citations -
EOMES and IL-10 regulate anti-tumor activity of PD-1 + CD4 + T-cells in B-cell Non-Hodgkin lymphoma2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Philipp M. Roessner, Laura Llaó Cid, Ekaterina Lupar, Tobias Roider, Marie Bordas, Christoph Schifflers, +10 more
4citations -
Counterfactual Diffusion Models for Interpretable Explanations of Artificial Intelligence Models in Pathology2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Explainable Artificial Intelligence (XAI) Open access
Laura Žigutytė, Tim Lenz, Tianyu Han, Katherine Jane Hewitt, Nic Gabriel Reitsam, Sebastian Foersch, +5 more
7citations -
A lymph node-to-tumour PDL1 + macrophage circuit antagonizes dendritic cell immunotherapy2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immunotherapy and Immune Responses Open access
Jenny Sprooten, Isaure Vanmeerbeek, Angeliki Datsi, Jannes Govaerts, Daniel Borràs, Stefan Naulaerts, +17 more
4citations -
Tertiary lymphoid structure-related immune infiltrates in NSCLC tumor lesions correlate with low tumor-reactivity of TIL products2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Suzanne M. Castenmiller, Nandhini Kanagasabesan, Aurélie Guislain, Benoît P. Nicolet, Marleen M. van Loenen, Kim Monkhorst, +6 more
0citations
20 results