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Engineering and application of a biosensor with focused ligand specificity2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Dennis Della Corte, Hugo L. van Beek, Falk Syberg, Marcus Schallmey, Felix Tobola, Kai U. Cormann, +9 more
110citations -
Directed evolution of VanR biosensor specificity in yeast2020 Biotechnology Notes article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Vasil D’Ambrosio, Subrata Pramanik, Kati Goroncy, Tadas Jakočiūnas, David Schönauer, Mehdi D. Davari, +3 more
29citations -
Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells2020 Journal of the American Chemical Society article Medicine Cannabis and Cannabinoid Research Open access cited by 3 patents
Roman C. Sarott, Matthias V. Westphal, Patrick Pfaff, Claudia Korn, David A. Sykes, Thais Gazzi, +51 more
51citations -
Enhanced Sampling Approach to the Induced-Fit Docking Problem in Protein–Ligand Binding: The Case of Mono-ADP-Ribosylation Hydrolase Inhibitors2021 Journal of Chemical Theory and Computation article Computer Science Computational Drug Discovery Methods Open access
Qianqian Zhao, Riccardo Capelli, Paolo Carloni, Bernhard Lüscher, Jinyu Li, Giulia Rossetti
28citations -
Development of a Biosensor Platform for Phenolic Compounds Using a Transition Ligand Strategy2021 ACS Synthetic Biology article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Lion Konstantin Flachbart, Christoph G. W. Gertzen, Holger Gohlke, Jan Marienhagen
23citations -
Spatial transcriptomics reveals molecular cues underlying the site specificity of the adult mouse oral mucosa and its stem cell niches2024 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Anna C. Seubert, Marion Krafft, Moutaz Helal, Pranjali Bhandare, Elmar Wolf, Anna Alemany, +2 more
11citations -
Accurate Prediction of GPCR Ligand Binding Affinity with Free Energy Perturbation2020 Journal of Chemical Information and Modeling article Computer Science Computational Drug Discovery Methods cited by 4 patents
Francesca Deflorian, Laura Pérez‐Benito, Eelke Bart Lenselink, Miles Congreve, Herman van Vlijmen, Jonathan S. Mason, +2 more
88citations -
Ligand–Receptor Interactions Elucidate Sex-Specific Pathways in the Trajectory From Primordial Germ Cells to Gonia During Human Development2021 Frontiers in Cell and Developmental Biology article Biochemistry, Genetics and Molecular Biology Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities Open access cited by 1 patent
Arend W. Overeem, Yolanda W. Chang, Jeroen Spruit, Celine M. Roelse, Susana M. Chuva de Sousa Lopes
23citations -
The Versatility of the Dicyanamide Anion (Dca) as a Bridging Ligand: Synthesis, Structure and Theory of a Unique Ladder Chain Consisting of 2 µ1,5-dca Bridged Dinuclear Cu2(dca)2 Units with Additional µ1,3-dca Bridges Along the Chain2024 Journal of Chemical Crystallography article Chemistry Crystal structures of chemical compounds Open access
Yaakoub Saadallah, Zouaoui Setifi, Hela Ferjani, Christopher Glidewell, Christian Jelsch, Fatima Setifi, +3 more
1citations -
CrossTalkeR: analysis and visualization of ligand–receptorne tworks2021 Bioinformatics article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
James Shiniti Nagai, Nils B. Leimkühler, Michael T. Schaub, Rebekka K. Schneider, Ivan G. Costa
58citations -
Localization and discrimination of GG mismatch in duplex DNA by synthetic ligand-enhanced protein nanopore analysis2024 Nucleic Acids Research article Engineering Nanopore and Nanochannel Transport Studies Open access
Wenping Lyu, Jianji Zhu, Xiaoqin Huang, Mauro Chinappi, Denis Garoli, Cenglin Gui, +1 more
6citations -
Imaging and photodynamic therapy of prostate cancer using a theranostic PSMA-targeting ligand2023 European Journal of Nuclear Medicine and Molecular Imaging article Medicine Photodynamic Therapy Research Studies Open access
Yvonne H. W. Derks, Melline G.M. Schilham, Mark Rijpkema, E. Smeets, Helene I. V. Amatdjais‐Groenen, Annemarie Kip, +10 more
16citations -
Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions2022 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Frank M. Speetjens, Marij J.P. Welters, Marije Slingerland, Mariëtte I.E. van Poelgeest, Peggy J. de Vos van Steenwijk, Inge C.F.M. Roozen, +13 more
39citations -
A new model of Notch signalling: Control of Notch receptor cis-inhibition via Notch ligand dimers2023 PLoS Computational Biology article Biochemistry, Genetics and Molecular Biology Developmental Biology and Gene Regulation Open access cited by 2 patents
Daipeng Chen, Zary Forghany, Xinxin Liu, Haijiang Wang, Roeland M. H. Merks, David A. Baker
20citations -
N-Acyl-N-Alkyl Sulfonamide Probes for Ligand-Directed Covalent Labeling of GPCRs: The Adenosine A2B Receptor as Case Study2024 ACS Chemical Biology article Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access
Bert L. H. Beerkens, Vasiliki Andrianopoulou, Xuesong Wang, Rongfang Liu, Gerard J. P. van Westen, Willem Jespers, +3 more
10citations -
Compositional and topological determinants of a physiological Ashwell–Morell receptor ligand2025 Proceedings of the National Academy of Sciences article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
John Hintze, Robert Fraumeni, Noortje de Haan, Rebecca Louise Miller, Mayank Saraswat, Zhang Yang, +2 more
3citations -
Impedance-based phenotypic profiling of metabotropic glutamate receptor ligand responses in SCA1 human iPSC-derived neuronal cultures2026 Neurobiology of Disease article Neuroscience Neuroscience and Neuropharmacology Research Open access
Laurie M.C. Kerkhof, Ronald A.M. Buijsen, Barry A. Pepers, Linda M. van der Graaf, Jean‐Philippe Frimat, Laura H. Heitman, +1 more
0citations -
A model of Notch signalling control of angiogenesis: Evidence of a role for Notch ligand heterodimerization2025 PLoS Computational Biology article Biochemistry, Genetics and Molecular Biology Developmental Biology and Gene Regulation Open access
Daipeng Chen, Xinxin Liu, Haijiang Wang, Roeland M. H. Merks, David A. Baker
12citations