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Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Estrogen and related hormone effects Open access
Laura Van Moortel, Jonathan Thommis, Brecht Maertens, An Staes, Dorien Clarisse, Delphine De Sutter, +5 more
3citations -
Pan-cancer in silico analysis of somatic mutations in G-protein coupled receptors: The effect of evolutionary conservation and natural variance2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer Genomics and Diagnostics Open access
Brandon J. Bongers, Marina Gorostiola González, X. Wang, Herman van Vlijmen, Willem Jespers, Hugo Gutiérrez‐de‐Terán, +4 more
3citations -
A universal cannabinoid CB1 and CB2 receptor TR-FRET kinetic ligand binding assay2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cannabis and Cannabinoid Research Open access
Leire Borrega Roman, Bradley L. Hoare, Miroslav Kosar, Roman C. Sarott, Kacper J. Patej, Jara Bouma, +15 more
0citations -
The helminth TGF-β mimic TGM4 is a modular ligand that binds CD44, CD49d and TGF-β receptors to preferentially target myeloid cells2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Parasites and Host Interactions Open access
Shashi Prakash Singh, Danielle J. Smyth, Kyle T. Cunningham, Ananya Mukundan, Chang‐Hyeock Byeon, Cynthia S. Hinck, +12 more
1citations -
Membrane Lipids and Water Shape the Unbinding Kinetics of ZM241385 from Human Adenosine A 2A Receptor Variants2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access
Marta Devodier, Davide Mandelli, Giulia Rossetti, Paolo Carloni
0citations -
Deciphering conformational selectivity in the A 2A adenosine G protein-coupled receptor by Free Energy simulations2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access
Willem Jespers, Laura H. Heitman, Adriaan P. IJzerman, Eddy Sotelo, Gerard J. P. van Westen, Johan Åqvist, +1 more
1citations -
Tumor-expressed SPPL3 supports innate anti-tumor immune responses2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Tamara Verkerk, Antonius A. de Waard, Sofie J. I. Koomen, Jasper Sanders, Tineke Jorritsma, Anouk T. Pappot, +7 more
2citations -
GraphComm: A Graph-based Deep Learning Method to Predict Cell-Cell Communication in single-cell RNAseq data2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Emily So, Sikander Hayat, Sisira Kadambat Nair, Bo Wang, Benjamin Haibe‐Kains
13citations -
Integrative single-cell and genetic profiling of human heart failure identifies targets for cardiomyocyte restoration2025 medRxiv preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Tore Bleckwehl, David Schumacher, Charlotte Heymanns, Sidrah Maryam, Sean Joseph Jurgens, Junedh Amrute, +13 more
1citations -
Structural modelling predicts that fibrocystin destabilisation is a pathogenic cause of ARPKD2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases Open access
Travis Bannell, Naveen Mathew, Kathrin Burgmaier, Max C. Liebau, Colin A. Johnson, Joseph J. B. Cockburn
0citations