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S-Ketamine Oral Thin Film—Part 1: Population Pharmacokinetics of S-Ketamine, S-Norketamine and S-Hydroxynorketamine2022 Frontiers in Pain Research article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Pieter Jan Simons, Erik Olofsen, Monique van Velzen, Maarten A. van Lemmen, René A. G. Mooren, Tom van Dasselaar, +5 more
15citations -
Nitric Oxide Donor Sodium Nitroprusside Reduces Racemic Ketamine─But Not Esketamine-Induced Pain Relief2024 ACS Pharmacology & Translational Science article Medicine Treatment of Major Depression Open access
Albert Dahan, Simone C. Jansen, Rutger M. van der Schrier, Elise Y. Sarton, David Dadiomov, Monique van Velzen, +2 more
9citations -
Pharmacological characterization of orally and intravenously administered (S-)ketamine in healthy humans: an apparent crucial role for (S-)ketamine and not its pharmacologically active metabolite (S-)norketamine in mediating acute NMDAR central nervous system effects up to 6 hours
Joost van Mechelen, Tobias Wieles, Laura G. J. M. Borghans, Maria Joanna Juachon, Amy L. Gillespie, Martijn S. van Noorden, +4 more
0citations -
Pharmacogenetic and drug interaction aspects on ketamine safety in its use as antidepressant ‐ implications for precision dosing in a global perspective2022 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Immaculate Mbongo Langmia, Katja Susanne Just, Sabrina Yamoune, Julian Peter Müller, Julia Stingl
40citations -
Predictive performance of parent-metabolite population pharmacokinetic models of (S)-ketamine in healthy volunteers2021 European Journal of Clinical Pharmacology article Medicine Pharmaceutical studies and practices Open access
Marije E. Otto, Kirsten Riber Bergmann, Gabriël E. Jacobs, Michiel Joost van Esdonk
2citations -
Increase in thalamic cerebral blood flow is associated with antidepressant effects of ketamine in major depressive disorder2022 The World Journal of Biological Psychiatry article Medicine Treatment of Major Depression Open access
Matti Gärtner, Mischa de Rover, Lena Václavů, Milan Scheidegger, Matthias J.P. van Osch, Simone Grimm
11citations -
Sustained pharmacodynamic effects of S‐ketamine on cortical excitability and resting‐state brain activity: A randomized, placebo‐controlled trial2026 British Journal of Clinical Pharmacology article Medicine Treatment of Major Depression Open access
Catherine M.K.E. de Cuba, Annika A. de Goede, Joost van Mechelen, Laura G. J. M. Borghans, Lazarenko Aa, Erik Olofsen, +6 more
0citations