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The difficulty to model Huntington’s disease in vitro using striatal medium spiny neurons differentiated from human induced pluripotent stem cells2021 Scientific Reports article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Kim Le Cann, Alec Foerster, Corinna Rösseler, Andelain Erickson, Petra A. I. Hautvast, Sebastian Gießelmann, +10 more
27citations -
Radiation Induces Valvular Interstitial Cell Calcific Response in an in vitro Model of Calcific Aortic Valve Disease2021 Frontiers in Cardiovascular Medicine article Medicine Cardiac Valve Diseases and Treatments Open access
Manon Meerman, Rob C. H. Driessen, Nicole C. A. van Engeland, Irith Bergsma, Jacco L. G. Steenhuijsen, David Kozono, +3 more
12citations -
Conditional immortalization of human cardiomyocytes for translational in vitro modelling of cardiovascular disease2022 Cardiovascular Research article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Niels J. Harlaar, Daniël A. Pijnappels, Antoine A.F. de Vries
1citations -
In Vitro Generation and Characterization of The Wu Syndrome Model That Causes Mental Retardation in Neural Cell Lines2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetics and Neurodevelopmental Disorders Open access
Sumeyye Seher Karaman, Tuba Sevik, Selin Akdemir, Esra Karadeli, Dilay Yalcin, Buse Baran, +5 more
0citations -
Editorial: Advances in pluripotent stem cell-based in vitro models of the human heart for cardiac physiology, disease modeling and clinical applications2024 Frontiers in Physiology editorial Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Maksymilian Prondzynski, Josè Manuel Pioner, Luca Sala, Milena Bellin, Viviana Meraviglia
1citations -
Differentiated mouse kidney tubuloids as a novel in vitro model to study collecting duct physiology2023 Frontiers in Cell and Developmental Biology article Biochemistry, Genetics and Molecular Biology Ion Transport and Channel Regulation Open access
Charlotte J.A. Olde Hanhof, Emre Dilmen, Fjodor A. Yousef Yengej, Femke Latta, Carola M. E. Ammerlaan, Juliët Schreurs, +6 more
6citations -
Exploratory Metabolomic Analysis Based on Reversed-Phase Liquid Chromatography–Mass Spectrometry to Study an In Vitro Model of Hypoxia-Induced Metabolic Alterations in HK-2 Cells2021 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access
Samuel Bernardo‐Bermejo, Elena Sánchez‐López, Lei Tan, Selma Benito Martínez, Zhengjin Jiang, María Castro‐Puyana, +2 more
6citations -
In vitro Three-Dimensional Sprouting Assay of Angiogenesis using Mouse Embryonic Stem Cells for Vascular Disease Modeling and Drug Testing2021 Journal of Visualized Experiments article Biochemistry, Genetics and Molecular Biology Angiogenesis and VEGF in Cancer cited by 2 patents
Georgios Galaris, Jérémy H. Thalgott, Eliott Teston, Franck Lebrin
4citations -
Drug Distribution in Brain and Cerebrospinal Fluids in Relation to IC50 Values in Aging and Alzheimer’s Disease, Using the Physiologically Based LeiCNS-PK3.0 Model2022 Pharmaceutical Research article Medicine Cholinesterase and Neurodegenerative Diseases Open access
Mohammed A. A. Saleh, Julia S. Bloemberg, Jeroen Elassaiss‐Schaap, Elizabeth C. M. de Lange
8citations -
3D Humanized Bioprinted Tubulointerstitium Model to Emulate Renal Fibrosis In Vitro2024 Advanced Healthcare Materials article Engineering 3D Printing in Biomedical Research Open access
Gabriele Addario, Julia Fernández‐Pérez, Chiara Formica, Konstantinos Karyniotakis, Lea Herkens, Sonja Djudjaj, +3 more
18citations -
A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease2021 International Journal of Molecular Sciences article Engineering 3D Printing in Biomedical Research Open access cited by 3 patents
Luuk de Haan, Johnny Suijker, Ruthger van Roey, Nina Berges, Elissaveta P. Petrova, Karla C. S. Queiroz, +5 more
83citations -
Role of LCN2 in a murine model of hindlimb ischemia and in peripheral artery disease patients, and its potential regulation by miR-138-5P2023 Atherosclerosis article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Goren Saenz‐Pipaon, Eva Jover, M. Leontien van der Bent, Josune Orbe, José Antonio Rodríguez, Amaya Fernández‐Celis, +6 more
8citations -
Interstitial Lung Disease in Patients With Systemic Sclerosis: Toward Personalized-Medicine-Based Prediction and Drug Screening Models of Systemic Sclerosis-Related Interstitial Lung Disease (SSc-ILD)
Padmini P. S. J. Khedoe, Emiel R. Marges, Pieter Sicco Hiemstra, Maarten K. Ninaber, Miranda Geelhoed
24citations -
Development of a Synthetic 3D Platform for Compartmentalized Kidney In Vitro Disease Modeling2025 Advanced Healthcare Materials article Engineering 3D Printing in Biomedical Research Open access
Ninon Möhl, Daphne Bouwens, Johanna Abele, A Heus Hans, Tanja Topic, Daniel Günther, +3 more
2citations -
Development of an In Vitro Airway Epithelial–Endothelial Cell Culture Model on a Flexible Porous Poly(Trimethylene Carbonate) Membrane Based on Calu-3 Airway Epithelial Cells and Lung Microvascular Endothelial Cells
Thijs Pasman, Danielle Baptista, Sander van Riet, Roman K. Truckenmüller, Pieter Sicco Hiemstra, Robbert J. Rottier, +4 more
31citations -
A Patient‐Derived 3D Cyst Model of Polycystic Kidney Disease That Mimics Disease Development and Responds to Repurposing Candidates2025 Clinical and Translational Science article Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases Open access
Alina Meyer, Margarita Iljin, Hester Bange, Leo Price, Natalia Dyubankova, Gerard J. P. van Westen, +3 more
3citations