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Preclinical assessment of two FcγRI-specific antibodies that competitively inhibit immune complex-FcγRI binding to suppress autoimmune responses2025 Nature Communications article Medicine Monoclonal and Polyclonal Antibodies Research Open access
Tosca Holtrop, Arianne M. Brandsma, Louris J. Feitsma, Steffen Krohn, Petra Moerer, Frederique van den Haak, +15 more
3citations -
496 Pre-clinical development of a TCRm antibody targeting MHC-E complexes presenting signal peptides from classical MHC class I disrupts the NKG2A:MHC-E immune checkpoint and promotes anti-tumor immunity2024 Regular and Young Investigator Award Abstracts conference-abstract Immunology and Microbiology Immune Cell Function and Interaction Open access
Soroush Ghaffari, Katherine Upchurch, Gizem Oter, Susanne Gimlin, Debra Wawro-Weidanz, Thorbald van Hall, +1 more
0citations -
Cell-Surface RNA Forms Ternary Complex with RNA-Binding Proteins and Heparan Sulfate to Recruit Immune Receptors2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Zeshi Li, Bhagyashree S. Joshi, Ruud H. M. Wijdeven, Irene Santos‐Barriopedro, Milad Shademan, Eric Bos, +5 more
4citations -
Antibody-Dependent Immune Complex Signaling and Inflammatory Cytokine Responses in Acute Febrile Illness: A Mechanistic Study in Arboviral and Leptospiral Infection2026 Open Forum Infectious Diseases article Medicine Mosquito-borne diseases and control Open access
Peter Mac Asaga, Vijeesh Kadukkatti, Philomena Ehi Airiohuodion, Brijil Mathew, Sunday Omilabu
0citations -
AP-1 complex activation is a conserved signature of immune system aging and a potential regulator of inflammaging in human and mice2021 Research Square preprint Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Emin Onur Karakaslar, Muneer G. Hasham, Neerja Katiyar, Ahrim Youn, Siddhartha Sharma, Cheng‐Han Chung, +4 more
0citations -
A Single-Domain TCR-like Antibody Selective for the Qa-1b/Qdm Peptide Complex Enhances Tumoricidal Activity of NK Cells via Blocking the NKG2A Immune Checkpoint2022 The Journal of Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Soroush Ghaffari, Katherine Upchurch, Susanne Gimlin, Trivendra Tripathi, Marjolein Sluijter, Jim Middelburg, +2 more
7citations -
Transcriptional activation of Jun and Fos members of the AP‐1 complex is a conserved signature of immune aging that contributes to inflammaging2023 Aging Cell article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Emin Onur Karakaslar, Neerja Katiyar, Muneer G. Hasham, Ahrim Youn, Siddhartha Sharma, Cheng‐Han Chung, +4 more
102citations -
Transcriptional activation of Jun and Fos members of the AP-1 complex is a conserved signature of immune aging that contributes to inflammaging2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Emin Onur Karakaslar, Neerja Katiyar, Muneer G. Hasham, Ahrim Youn, Siddhartha M. Sharma, Cheng‐Han Chung, +4 more
6citations -
DNA Nanostructure-Templated Antibody Complexes Provide Insights into the Geometric Requirements of Human Complement Cascade Activation2024 Journal of the American Chemical Society article Immunology and Microbiology Complement system in diseases Open access
Leoni Abendstein, Willem E. M. Noteborn, Luc S. Veenman, Douwe J. Dijkstra, Fleur S. van de Bovenkamp, Leendert Adrianus Trouw, +1 more
16citations -
IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming2020 The Journal of Immunology article Medicine Monoclonal and Polyclonal Antibodies Research Open access
Willianne Hoepel, Sona Allahverdiyeva, Haneen Harbiye, Steven W. de Taeye, Alwin J. van der Ham, Leonie de Boer, +7 more
23citations -
Molecular characterization of the RNA-protein complex directing −2/−1 programmed ribosomal frameshifting during arterivirus replicase expression2020 Journal of Biological Chemistry article Biochemistry, Genetics and Molecular Biology RNA and protein synthesis mechanisms Open access
Ankoor Patel, Emmely E. Treffers, Markus Meier, Trushar R. Patel, Jörg Stetefeld, Eric J. Snijder, +1 more
15citations -
A powdery mildew core effector protein targets host endosome tethering complexes HOPS and CORVET2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Agricultural and Biological Sciences Powdery Mildew Fungal Diseases Open access
Björn Sabelleck, Sohini Deb, Pietro D. Spanu, Hans Thordal‐Christensen, Ralph Panstruga
2citations -
A powdery mildew core effector protein targets the host endosome tethering complexes HOPS and CORVET in barley2025 PLANT PHYSIOLOGY article Agricultural and Biological Sciences Powdery Mildew Fungal Diseases Open access
Björn Sabelleck, Sohini Deb, Sophie C. J. Levecque, Matthias Freh, Anja Reinstädler, Pietro D. Spanu, +2 more
11citations -
P0123 The immune system of patients with immune-mediated diseases perceives dysbiotic intestinal microbial species, and IgG reactivity uncovers shared and non-shared responses across diseases2025 Journal of Crohn s and Colitis conference-abstract Biochemistry, Genetics and Molecular Biology Gut microbiota and health
Daniëlle M.H. Barendregt, Ranko Gaćeša, Niels Plomp, B Calado, Arno R. Bourgonje, Julia I. P. van Heck, +10 more
2citations