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Temporal and spatial composition of the tumor microenvironment predicts response to immune checkpoint inhibition2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Noah F. Greenwald, Iris Nederlof, Daisy Yi Ding, Seongyeol Park, Alex Kong, Kathleen E. Houlahan, +29 more
7citations -
Tertiary lymphoid structure-related immune infiltrates in NSCLC tumor lesions correlate with low tumor-reactivity of TIL products2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Suzanne M. Castenmiller, Nandhini Kanagasabesan, Aurélie Guislain, Benoît P. Nicolet, Marleen M. van Loenen, Kim Monkhorst, +6 more
0citations -
Computational modelling of cell motility modes emerging from cell-matrix adhesion dynamics2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Leonie van Steijn, Clément Sire, Loı̈c Dupré, Guy Théraulaz, Roeland M. H. Merks
4citations -
Neonatal Peyer’s patch cDC activation as a pacemaker of postnatal immune maturation2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immunotherapy and Immune Responses Open access
Natalia Torow, R. Li, Thomas C. A. Hitch, Clemens Mingels, Shahed Al Bounny, Niels van Best, +16 more
1citations -
Germline genetic contribution to the immune landscape of cancer2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Rosalyn W. Sayaman, Mohamad Saad, Vésteinn Thórsson, Wouter Hendrickx, Jessica P Roelands, Younes Mokrab, +18 more
21citations -
NK cell-macrophage interactions in granulomas correlate with limited tuberculosis pathology2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberculosis Research and Epidemiology Open access
Paula Niewold, Marieke E. Ijsselsteijn, Karin Dijkman, Noel F.C.C. de Miranda, Tom H. M. Ottenhoff, Frank A. W. Verreck, +1 more
0citations -
Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access
Farooq Syed, Olivia Ballew, Chih‐Chun Lee, Jyoti Rana, Preethi Krishnan, Ângela Castela, +16 more
3citations -
PD1+ T-cells correlate with Nerve Fiber Density as a prognostic biomarker in patients with resected perihilar cholangiocarcinoma2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cholangiocarcinoma and Gallbladder Cancer Studies Open access
Xiuxiang Tan, Mika Rosin, Simone Appinger, Jan Bednarsch, Dong Liu, Georg J. Wiltberger, +19 more
1citations -
Single-cell characterization of human periodontal ligament (PDL) cells reveals uniformly mesenchymal populations in matched maxilla and mandible pairs from four donors2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Periodontal Regeneration and Treatments Open access
Chloé Radermacher, Robert Dzhanaev, Christian Hasberg, Sabine Neuß-Stein, Andrea Gorgels, Julia Moellmann, +8 more
0citations -
Pharmacological Inhibition of Tyrosine Protein-Kinase 2 Reduces Islet Inflammation and Delays Type 1 Diabetes Onset in Mice2024 SSRN Electronic Journal preprint Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access
Farooq Syed, Olivia Ballew, Chih‐Chun Lee, Jyoti Rana, Preethi Krishnan, Ângela Castela, +16 more
3citations -
Compartment-specific remodeling of skeletal muscle in Duchenne muscular dystrophy2026 Research Square preprint Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Clara Martínez Mir, Paola Pisterzi, Isabel de Poorter, Jamilla Beek, Anna Alemany, Fanny Sage, +1 more
0citations -
Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Colorectal Cancer Treatments and Studies Open access
Christina Plattner, Giorgia Lamberti, Peter Blattmann, Alexander Kirchmair, Dietmar Rieder, Zuzana Loncová, +23 more
0citations -
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Afrizal Afrizal, Susan A. V. Jennings, Thomas C. A. Hitch, Marijana Basic, Atscharah Panyot, Nicole Simone Treichel, +18 more
9citations -
DRAG in situ barcoding reveals an increased number of HSPCs contributing to myelopoiesis with age2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Hematopoietic Stem Cell Transplantation Open access
Jos H. M. Urbanus, Jason Cosgrove, Joost B. Beltman, Yuval Elhanati, Rafael de Andrade Moral, Cécile Conrad, +13 more
1citations -
Distinct Effects of the Extracellular Matrix on Tumor Organization and Response to Cancer Virotherapy2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Frederique Visscher, Annemarie Boerma, Anne K. Wouters, Manas Joshi, Mirjam H.M. Heemskerk, Darshak Bhatt
0citations -
Correcting differential gene expression analysis for cyto-architectural alterations in substantia nigra of Parkinson’s disease patients reveals known and potential novel disease-associated genes and pathways2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Parkinson's Disease Mechanisms and Treatments Open access
Federico Ferraro, Fevga Christina, Bonifati Vincenzo, Mandemakers Wim, Mahfouz Ahmed, Reinders Marcel
0citations -
Vascular niches are the primary hotspots for aging within the multicellular architecture of cardiac tissue2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cardiac Fibrosis and Remodeling Open access
David Rodríguez Morales, Veronica Larcher, Mariano Ruz Jurado, Lukas Stefan Tombor, Lukas Zanders, Julian U. G. Wagner, +5 more
0citations -
Spatial Transcriptomic Characterization of Novel Pathologic Niches in IPF2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Open access
Christoph H. Mayr, Diana Santacruz, Sebastian Jarosch, Charlotte Lempp, Lavinia Neubert, Berenice Rath, +7 more
1citations -
Depletion of the RNA-binding protein PURA triggers changes in posttranscriptional gene regulation and loss of P-bodies2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Lena Molitor, Melina Klostermann, Sabrina Bacher, Juliane Merl‐Pham, Nadine Spranger, Sandra Burczyk, +15 more
0citations -
A conserved glycan motif overcomes antigenic variation inducing broadly reactive antibodies against the zoonotic pathogen Streptococcus suis2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Streptococcal Infections and Treatments Open access
Yao Shi, Göran Widmalm, Charlotte Sorieul, Thomas J. Roodsant, Jeffrey S. Rush, Natalia Korotkova, +15 more
0citations -
Totum-448, a polyphenol-rich plant extract, decreases hepatic steatosis and inflammation in diet-induced MASLD mice2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver Disease Diagnosis and Treatment Open access
Joost M. Lambooij, Vivien Chavanelle, Marie Vallier, Hendrik J.P. van der Zande, Yolanda F. Otero, Frank Otto, +7 more
0citations