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Systematic comparison of temporal transcriptional responses to hepatotoxicants in primary human hepatocytes and HepaRG cells using concentration-response modelling of gene co-expression networks2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Steven J. Kunnen, Emma Arnesdotter, Christian Tobias Willenbockel, Mathieu Vinken, Bob van de Water
0citations -
Balance Between EGF/STAT1 and IFNγ/NRF2 Signaling Controls ECM1 Expression and Determines Hepatic Homeostasis versus Chronic Liver Disease2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver physiology and pathology Open access
Yujia Li, Chenjun Huang, Weiguo Fan, Seddik Hammad, Lea Berger, Cyrill Géraud, +18 more
0citations -
SAHA increases chaperone expression and reduces Z-alpha-1-antitrypsin polymers in a patient specific iPSC-based liver model for alpha-1-antitrypsin deficiency2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Endoplasmic Reticulum Stress and Disease Open access
Nina Graffmann, Rabea Hokamp, Christiane Loerch, Malin Fromme, Wasco Wruck, Pavel Strnad, +1 more
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Early but not late exercise training in mice exacerbates hepatic inflammation in early NAFLD2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver Disease Diagnosis and Treatment Open access
Artemiy Kovynev, Zhixiong Ying, Joost M. Lambooij, Bruno Guigas, Patrick C.N. Rensen, Milena Schönke
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The interplay of TGF-β1 and cholesterol orchestrating hepatocyte cell fate, EMT, and signals for HSC activation2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver physiology and pathology Open access
Sai Wang, Frederik Link, Mei Han, Roohi Chaudhary, Anastasia Asimakopoulos, Roman Liebe, +11 more
1citations -
The cell cycle regulator Cyclin E1 drives macrophage-associated inflammatory responses in acute immune-mediated hepatitis2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver physiology and pathology Open access
Christian Penners, Cheng Lin, Alexander Jans, Antje Mohs, Frank Tacke, Matthias Bartneck, +2 more
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The FXR agonist obeticholic acid does not stimulate liver regeneration in hepatectomized mice2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver physiology and pathology Open access
Kim M.C. van Mierlo, Carola Dahrenmöller, Valérie Lebrun, Peter L. M. Jansen, Cornelis H.C. Dejong, Isabelle Anne Leclercq, +2 more
0citations
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