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GeneSurfer Enables Transcriptome-wide Exploration and Functional Annotation of Gene Co-expression Modules in 3D Spatial Transcriptomics Data2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Chang Li, Julian Thijssen, Thomas Kroes, Ximaine R. van der Burg, Louise van der Weerd, Thomas Höllt, +1 more
0citations -
Fold first, ask later: structure-informed function annotation of Pseudomonas phage proteins2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Environmental Science Bacteriophages and microbial interactions Open access
Hannelore Longin, George Spyro Bouras, Susanna R. Grigson, Robert Alan Edwards, Hanne Hendrix, Rob Lavigne, +1 more
0citations -
Analysis of pre-symptomatic Drosophila models for ALS and SMA reveals convergent impact on functional protein complexes linked to neuro-muscular degeneration2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Amyotrophic Lateral Sclerosis Research Open access
Marina L. García‐Vaquero, Barbara Flix, Marcelo Henrique Neves Pereira, Lucile Palin, Tânia Monteiro Marques, Francisco Rodrigues Pinto, +4 more
0citations -
Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Jeffrey Wang, Jung Min Suh, Brian J Woo, Albertas Navickas, Kristle Garcia, Keyi Yin, +10 more
7citations -
Structural and functional characterization of SARS-CoV-2 RBD domains produced in mammalian cells2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access
Christoph Gstöttner, Tao Zhang, Anja Resemann, Sophia Ruben, Stuart Pengelley, Detlev Suckau, +3 more
5citations -
Elucidating another level of epigenetic regulation in osteoarthritis by identifying functional cis -acting long non-coding RNAs and their targets in articular cartilage2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Osteoarthritis Treatment and Mechanisms Open access
Marcella van Hoolwerff, Paula I. Metselaar, Margo Tuerlings, H. Eka D. Suchiman, Nico Lakenberg, Y.F. Ramos, +6 more
0citations -
Roles for the long non-coding RNA Pax6os1 / PAX6-AS1 in pancreatic beta cell identity and function2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Pancreatic function and diabetes Open access
Livia López–Noriega, Rebecca Callingham, Aida Martínez-Sánchez, Sameena Nawaz, Grazia Pizza, Nejc Haberman, +13 more
6citations -
Investigating Enzyme Function by Geometric Matching of Catalytic Motifs2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Ioannis G. Riziotis, Martin F. Larralde, António J. M. Ribeiro, Georg Zeller, Janet M. Thornton
2citations -
SynCom101: A web-based platform for the standardized design of functionally tailored synthetic microbial communities2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health
Jiayi Jing, Siemen Rockx, Aster Liu, Chrats Melkonian, Jos M. Raaijmakers, Paolina Garbeva, +1 more
0citations -
On distinguishing between canonical tRNA genes and tRNA gene fragments in prokaryotes2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA and protein synthesis mechanisms Open access
Peter T. S. van der Gulik, Martijn Egas, Ken Kraaijeveld, Nina Dombrowski, Astrid T. Groot, Anja Spang, +2 more
0citations -
A comprehensive mouse kidney atlas enables rare cell population characterization and robust marker discovery2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Claudio Novella-Rausell, Magda Grudniewska, Dorien J.M. Peters, Ahmed Essam Mahfouz
5citations -
2D, or not 2D? Investigating Vertical Signal Integrity of Tissue Slices2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Sebastian Tiesmeyer, Niklas Müller‐Bötticher, Sergio Marco Salas, Paul Kießling, Paul M. Horn, Adrien Guillot, +7 more
9citations -
The Human Pancreas Cell Atlas defines a healthy reference framework for disease contextualization and translational benchmarking2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics
Shrey Parikh, Daniel C. Strobl, Sara Jiménez, Julia Beckmann, Lucas Arnoldt, Eljas Roellin, +18 more
0citations -
Trio-based whole exome sequencing in patients with suspected sporadic inborn errors of immunity: a retrospective cohort study2022 medRxiv preprint Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access
Anne Hebert, Annet Simons, Janneke H. M. Schuurs-Hoeijmakers, Hans J. P. M. Koenen, Evelien Zonneveld‐Huijssoon, Stefanie Henriet, +14 more
2citations -
Plasma triacylglycerol length and saturation level mark healthy aging groups in humans2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Lipid metabolism and biosynthesis Open access
Weisha Li, Bauke V. Schomakers, Michel van Weeghel, Lotte Grevendonk, Frédéric Maxime Vaz, Gajja Sophi Salomons, +5 more
0citations -
Epigenome-wide change and variation in DNA methylation from birth to late adolescence2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Rosa H. Mulder, Alexander Neumann, Charlotte A. M. Cecil, Esther Walton, Lotte C. Houtepen, Andrew J. Simpkin, +10 more
5citations -
Asymptomatic gut colonization by extended-spectrum beta-lactamase-producing Escherichia coli is not associated with an altered gut microbiome or metabolome in Dutch adults2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Quinten R. Ducarmon, Romy Daniëlle Zwittink, Roel P J Willems, Aswin Verhoeven, Sam Nooij, Fiona R.M. van der Klis, +6 more
1citations