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Exploring the therapeutic potential of a novel series of imidazothiadiazoles targeting focal adhesion kinase (FAK) for pancreatic cancer treatment: synthesis, mechanistic insights and promising antitumor and safety profile
Camilla Pecoraro, Daniela Carbone, Fabio Scianò, Francesca Terrana, Geng Xu, Cecilia Bergonzini, +6 more
14citations -
ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration2024 Molecular Oncology article Biochemistry, Genetics and Molecular Biology Mechanisms of cancer metastasis Open access
Jennifer R. Kosinski, Antonio S. Sechi, Sophia Villwock, Stefanie Anh Ha, Maximilian Hauschulz, Michael Rose, +12 more
14citations -
Expression levels of the metalloproteinase ADAM8 critically regulate proliferation, migration and malignant signalling events in hepatoma cells2020 Journal of Cellular and Molecular Medicine article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Tanzeela Awan, Aaron Babendreyer, Abid Mahmood Alvi, Stefan Düsterhöft, Daniela Lambertz, Jörg Walter Bartsch, +2 more
37citations -
FAK inhibition radiosensitizes pancreatic ductal adenocarcinoma cells in vitro2020 Strahlentherapie und Onkologie article Medicine Pancreatic and Hepatic Oncology Research Open access cited by 2 patents
Ahmed Allam Mohamed, Andreas R. Thomsen, Marie Follo, Costantinos Zamboglou, Peter Bronsert, Aber Amen, +2 more
26citations -
Biophysical Modulation of the Mitochondrial Metabolism and Redox in Bone Homeostasis and Osteoporosis: How Biophysics Converts into Bioenergetics2021 Antioxidants article Biochemistry, Genetics and Molecular Biology Bone Metabolism and Diseases Open access
Feng‐Sheng Wang, Re‐Wen Wu, Yushan Chen, Jih‐Yang Ko, Holger Jahr, Wei‐Shiung Lian
62citations -
Downregulation of miR‐193a/b‐3p during HPV‐induced cervical carcinogenesis contributes to anchorage‐independent growth through PI3K–AKT pathway regulators2023 Journal of Medical Virology article Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Mengfei Xu, Angelina Huseinovic, Annelieke Jaspers, Lushun Yuan, Renske D.M. Steenbergen
15citations
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