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Structure and Cooperativity in Substrate–Enzyme Interactions: Perspectives on Enzyme Engineering and Inhibitor Design2022 ACS Chemical Biology article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization
Eerappa Rajakumara, Suman Abhishek, Kulhar Nitin, Dubey Saniya, Priyanka Bajaj, Ulrich Schwaneberg, +1 more
47citations -
Effects of urease inhibitor 2-NPT and nitrification inhibitors DMPP and MPA on soil microbial communities: an incubation study2026 Environmental Sciences Europe article Agricultural and Biological Sciences Soil Carbon and Nitrogen Dynamics Open access
Martin Siedt, Amaru B. Ponton Paul, Matthias Franck, Inga Brill, Larissa K. Drews, Alexander Nothbaum, +5 more
1citations -
Effects of urease inhibitor 2-NPT and nitrification inhibitors DMPP and MPA on soil microbial communities: an incubation study2026 Figshare other Agricultural and Biological Sciences Soil Carbon and Nitrogen Dynamics Open access
Martin Siedt, Amaru B. Ponton Paul, Matthias Franck, Inga Brill, Larissa K. Drews, Alexander Nothbaum, +5 more
0citations -
Effects of urease inhibitor 2-NPT and nitrification inhibitors DMPP and MPA on soil microbial communities: an incubation study2026 Figshare other Agricultural and Biological Sciences Soil Carbon and Nitrogen Dynamics Open access
Martin Siedt, Amaru B. Ponton Paul, Matthias Franck, Inga Brill, Larissa K. Drews, Alexander Nothbaum, +5 more
0citations -
Mechanistic Investigations of Metallo-β-Lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition2020 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access
Nicola Wade, Kamaleddin H. M. E. Tehrani, Nora C. Brüchle, Matthijs J. van Haren, Vida Mashayekhi, Nathaniel I. Martin
0citations -
Mechanistic Investigations of Metallo-β-Lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition2020 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access
Nicola Wade, Kamaleddin H. M. E. Tehrani, Nora C. Brüchle, Matthijs J. van Haren, Vida Mashayekhi, Nathaniel I. Martin
1citations -
Mechanistic Investigations of Metallo‐β‐lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition**2021 ChemMedChem article Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access
Nicola Wade, Kamaleddin H. M. E. Tehrani, Nora C. Brüchle, Matthijs J. van Haren, Vida Mashayekhi, Nathaniel I. Martin
33citations -
Synthesis of Stable NAD+ Mimics as Inhibitors for the Legionella pneumophila Phosphoribosyl Ubiquitylating Enzyme SdeC2020 ChemBioChem article Biochemistry, Genetics and Molecular Biology Biochemical and Molecular Research Open access cited by 1 patent
Jerre M. Madern, Robbert Q. Kim, Mohit Misra, Ivan Đikić, Yong Zhang, Huib Ovaa, +3 more
11citations -
Small Molecule Inhibitors of Nicotinamide N-Methyltransferase Enzyme for the Treatment of Osteosarcoma and Merkel Cell Carcinoma: Potential for the Development of a Targeted Therapeutic Strategy2025 Biomolecules article Biochemistry, Genetics and Molecular Biology RNA modifications and cancer Open access
Veronica Pompei, Monia Cecati, Emma Nicol Serritelli, Eleonora Gerini, Roberto Campagna, Valentina Pozzi, +4 more
3citations -
Manno- epi -cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors2020 Journal of the American Chemical Society article Chemistry Carbohydrate Chemistry and Synthesis Open access
Zachary Armstrong, C.J. Kuo, D. Lahav, Rachel D. Johnson, Thomas J. M. Beenakker, Casper de Boer, +14 more
47citations -
How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition—The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine2020 Molecules article Biochemistry, Genetics and Molecular Biology Synthesis and bioactivity of alkaloids Open access
Anne Wurzlbauer, Katharina Rüben, Enise Ece Gürdal, A. Chaikuad, Stefan Knapp, Wolfgang Sippl, +2 more
14citations -
Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent β‐ l‐ Arabinofuranosidase Inhibitor2021 Angewandte Chemie International Edition article Chemistry Carbohydrate Chemistry and Synthesis Open access
Nicholas G. S. McGregor, Joan Coines, Valentina Borlandelli, Satoko Amaki, Marta Artola, Alba Nin‐Hill, +11 more
25citations -
Highly Selective Sub-Nanomolar Cathepsin S Inhibitors by Merging Fragment Binders with Nitrile Inhibitors2020 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms cited by 10 patents
Markus Schade, Beatrix Merla, Bernhard Lesch, Markus Wagener, Simone Timmermanns, Katrien Pletinckx, +1 more
15citations -
Optimization of 2,3-dihydrophthalazine-1,4-dione PARP inhibitor scaffold for nanomolar potency and specificity towards human PARP102025 European Journal of Medicinal Chemistry article Medicine PARP inhibition in cancer therapy Open access
Juho Alaviuhkola, Maria Giulia Nizi, Chiara Vagaggini, Chiara Sarnari, Barbara E. Lippok, Mirko M. Maksimainen, +8 more
1citations -
Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining α- l -Arabinofuranosidases2020 Journal of the American Chemical Society article Chemistry Carbohydrate Chemistry and Synthesis Open access
Nicholas G. S. McGregor, Marta Artola, Alba Nin‐Hill, Daniël Linzel, Mireille Haon, Jos Reijngoud, +9 more
50citations -
Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor2022 Communications Biology article Biochemistry, Genetics and Molecular Biology Polyamine Metabolism and Applications Open access cited by 1 patent
Elsie Diaz, Suraj Adhikary, Armand W.J.W. Tepper, Daniel Riley, Rodrigo F. Ortiz‐Meoz, Daniel J. Krosky, +12 more
11citations -
Inhibiting UCH-L5: Rational Design of a Cyclic Ubiquitin-Based Peptide Inhibitor2022 Frontiers in Molecular Biosciences article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Dharjath S. Hameed, Huib Ovaa, Gerbrand J. van der Heden van Noort, Ayşegül Sapmaz
2citations