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Early discontinuation of PD-1 blockade upon achieving a complete or partial response in patients with advanced melanoma: the multicentre prospective Safe Stop trial
Evalyn E.A.P. Mulder, Karlijn de Joode, Saskia Litière, Albert J. ten Tije, Karijn P.M. Suijkerbuijk, M. J. Boers‐Sonderen, +16 more
50citations -
Safe Stop IPI-NIVO trial: early discontinuation of nivolumab upon achieving a complete or partial response in patients with irresectable stage III or metastatic melanoma treated with first-line ipilimumab-nivolumab – study protocol
Brigit van Dijk, Karlijn de Joode, Maureen J.B. Aarts, Franchette W.P.J. van den Berkmortel, Christian U. Blank, M. J. Boers‐Sonderen, +15 more
7citations -
Correction: Designing integrated early-phase protocols to reduce substantial modifications, including considerations for patient cohorts – a multi-stakeholder consensus view for a practical approach in Germany2026 Frontiers in Pharmacology erratum Mathematics Statistical Methods in Clinical Trials Open access
R. Schultz-Heienbrok, S. Baumann, R. Böhm, A. Bonertz, K. Breithaupt-Groegler, U. Buckpesch-Heberer, +13 more
0citations -
The potential value of disease-modifying therapy in patients with spinocerebellar ataxia type 1: an early health economic modeling study2023 Journal of Neurology article Economics, Econometrics and Finance Health Systems, Economic Evaluations, Quality of Life Open access
Teije H. van Prooije, Sanne Ruigrok, Niels van den Berkmortel, Roderick P.P.W.M. Maas, Stan R. W. Wijn, Willeke van Roon‐Mom, +2 more
3citations -
Sustained Remission and Outcomes with Abatacept plus Methotrexate Following Stepwise Dose De-escalation in Patients with Early Rheumatoid Arthritis2023 Rheumatology and Therapy article Medicine Rheumatoid Arthritis Research and Therapies Open access
Paul E. Emery, Yoshiya Tanaka, Vivian P. Bykerk, Gustavo Citera, Clifton O. Bingham, Subhashis Banerjee, +8 more
16citations -
Authors’ reply re: Universal screening versus risk-based protocols for antibiotic prophylaxis during childbirth to prevent early-onset Group B streptococcal disease: A systematic review and meta-analysis. (Response to BJOG-20-0383)
Geke Hasperhoven, Salwan Al‐Nasiry, Vincent Bekker, Eduardo Villamor, Boris W. Kramer
0citations -
The incidence of early recurrent venous thromboembolism: a systematic review and meta-analysis2025 Research and Practice in Thrombosis and Haemostasis review Medicine Venous Thromboembolism Diagnosis and Management Open access
Lisbeth Eischer, Paul Alexander Kyrle, Alexandra Kaider, A. Schmidt, Brigitte Wildner, Anja Boc, +15 more
1citations -
Early DAS response after DMARD-start increases probability of achieving sustained DMARD-free remission in rheumatoid arthritis2020 Arthritis Research & Therapy article Medicine Rheumatoid Arthritis Research and Therapies Open access
Marloes Verstappen, Ellis Niemantsverdriet, X. Matthijssen, Saskia le Cessie, Annette H M van der Helm–van Mil
22citations -
Targeting for Success: Demonstrating Proof-of-Concept with Mechanistic Early Phase Clinical Pharmacology Studies for Disease-Modification in Neurodegenerative Disorders2021 International Journal of Molecular Sciences article Medicine Alzheimer's disease research and treatments Open access
Maurits F. J. M. Vissers, Jules A. A. C. Heuberger, Geert Jan Groeneveld
22citations -
CYP2D6 Metabolizer Phenotype Is Associated with Early Antidepressant Discontinuation in the UK Biobank2026 Pharmaceuticals article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Tehila Cohen, Estee Rebibo Demry, Allan Hunter Young, Kristian Kleine Schaars, Mário F. Juruena, Thomas G. Schulze, +3 more
0citations -
Early experience with selexipag for the treatment of adults with pulmonary arterial hypertension associated with congenital heart disease2020 European Heart Journal article Medicine Pulmonary Hypertension Research and Treatments Open access
Alexandra C. van Dissel, Martijn C. Post, Gertjan T. Sieswerda, Hubert Willem Vliegen, Arie P.J. van Dijk, A.L. Duijnhouwer, +2 more
1citations -
Exome sequencing links the SUMO protease SENP7 with fatal arthrogryposis multiplex congenita, early respiratory failure and neutropenia2023 Journal of Medical Genetics article Biochemistry, Genetics and Molecular Biology Genomics and Rare Diseases Open access
Nadra Nasser Samra, Nicolette S. Jansen, Ilham Morani, Reli Rachel Kakun, Rinat Zaid, Tamar Paperna, +14 more
8citations