Papers matching “drug combination screening” 16
Not finding it? Sign in to also search OpenAlex live.
-
A Framework for NGN1-Induced Sensory Neuron Differentiation for Disease Modelling and Drug Screening2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Anika Neureiter, Marlene Menke, Veronica Donde, Cedric Guenther, Lennart Mueller, Florian Kraft, +10 more
0citations -
Combi-Seq: Multiplexed transcriptome-based profiling of drug combinations using deterministic barcoding in single-cell droplets2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Lukas Mathur, Bence Szalai, Ramesh Utharala, Martine Ballinger, Jonathan J. M. Landry, Michaël Ryckelynck, +3 more
4citations -
Pandemic Drugs at Pandemic Speed: Infrastructure for Accelerating COVID-19 Drug Discovery with Hybrid Machine Learning- and Physics-based Simulations on High Performance Computers2021 arXiv (Cornell University) preprint Computer Science Computational Drug Discovery Methods Open access
Agastya P. Bhati, Shunzhou Wan, Austin Clyde, Mathis Bode, Mikhail Titov, André Merzky, +20 more
42citations -
Integration of In Vitro and In Silico Approaches Enables Prediction of Drug-Induced Liver Injury2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
René Geci, Ahenk Zeynep Sayin, Stephan Schaller, Lars Kuepfer
0citations -
Fi-score: a novel approach to characterise protein topology and aid in drug discovery studies2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access
Austė Kanapeckaitė, Claudia Beaurivage, MATTHEW J. HANCOCK, Erik Verschueren
2citations -
A NanoBRET-based assay monitoring interactions in the USP18 signaling hub identifies the first cell-penetrant small molecule compromising USP18/ISG15 binding2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology interferon and immune responses Open access
Sandra Hess, Marta Campos Alonso, Michael J. D. Brand, Susan Lauw, Urs Lindenmann, Paul P. Geurink, +3 more
6citations -
Machine Learning-aided Discovery of Novel Chemotype Antagonists for G Protein-coupled Receptors: The Case of the Adenosine A 2A Receptor2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access
Jonas Goßen, Rui Pedro Ribeiro, Dirk DB Bier, Bernd Neumaier, Paolo Carloni, Alejandro Giorgetti, +1 more
2citations -
Novel high throughput 3D ECM remodeling assay identifies MEK as key driver of fibrotic fibroblast activity2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Chen‐Yi Liao, Jasmijn H.M. Hundscheid, Justin Crawford, Peter ten Dijke, Beatrice Coorneaert, Erik H.J. Danen
0citations -
EZH2 Inhibition Sensitizes BRCA1-Deficient Breast Cancer to Synthetic Lethal Therapy with ATM Inhibitors2021 Research Square preprint Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Leonie Ratz, Chiara Svetlana Brambillasca, Leandra Bartke, Marieke van de Ven, Natalie Proost, Bjørn Siteur, +12 more
0citations -
Barcode-free hit discovery from massive libraries enabled by automated small molecule structure annotation2025 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access
Edith van der Nol, Nicola Haupt, Benthe A. M. Smit, Martin Andre Hoffmann, Martin S. Engler, Marcus Ludwig, +8 more
0citations -
Chemo-phosphoproteomic profiling with ATR inhibitors berzosertib and gartisertib uncovers new biomarkers and DNA damage response regulators2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Rathan S Jadav, Florian Weiland, Sylvie M. Noordermeer, Thomas D. Carroll, Yuandi Gao, Jianming Wang, +12 more
1citations -
Plasmodium falciparum SET10 is a histone H3 lysine K18 methyltransferase that participates in a chromatin modulation network crucial for intraerythrocytic development2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Malaria Research and Control Open access
Jean-Pierre Musabyimana, Sherihan Musa, Janice Manti, Ute Distler, Stefan Tenzer, Che Julius Ngwa, +1 more
0citations -
Ten numbers from the Laplace–Beltrami spectrum facilitate training-free classification of protein structures based on surface shape2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Miriam Fernández-Giro Muñoz, Jessica Emonts, Benjamin Berkels, Johannes F. Buyel
0citations
16 results