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Revisiting Acyclovir Dosing for Adult Viral Encephalitis Using a Full Bayesian LeiCNS PBPK Modeling Approach2025 Clinical Pharmacokinetics article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Tingjie Guo, Martijn L. Manson, Anne‐Grete Märtson, Jacob Bodilsen, Elizabeth C. M. de Lange
3citations -
Does nonlinear blood-brain barrier transport matter for (lower) morphine dosing strategies?2023 European Journal of Pharmaceutical Sciences article Medicine Pain Management and Opioid Use Open access
Berfin Gülave, Divakar Budda, Mohammed A. A. Saleh, J. G. Coen van Hasselt, Elizabeth C. M. de Lange
4citations -
Real‐world study on fluoropyrimidine‐related toxicity outcomes in cancer patients with select DPYD variant alleles that received DPYD genotype‐guided dosing2025 International Journal of Cancer article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Sofía L. J. Peeters, Didier Meulendijks, Zerina Kadric, Sara Ibrovic, Geert‐Jan Creemers, Vanja Milosevic, +7 more
6citations -
Attitudes and Practices Regarding Dosing Interval Extension of Biologics in Severe Asthma: A Nationwide Survey and Real-World Data From the Dutch RAPSODI Registry2026 The Journal of Allergy and Clinical Immunology In Practice article Medicine Asthma and respiratory diseases Open access
Camiel J M Marijnissen, Jacob K. Sont, Fleur L. Meulmeester, Michel W.J.M. Wouters, Gert‐Jan Braunstahl, Arnoud F Aldenkamp, +26 more
0citations -
Influence of personalized extended interval dosing on the natalizumab wearing-off effect - a sub-study of the NEXT-MS trial2024 Journal of the Neurological Sciences article Medicine Multiple Sclerosis Research Studies Open access
Alyssa A Toorop, Mark HJ Wessels, Liza M. Y. Gelissen, Elske Hoitsma, E.M.P.E. Zeinstra, Luuk C van Rooij, +24 more
7citations -
A randomised, single-blind, placebo-controlled, dose-finding safety and tolerability study of the anti-CD3 monoclonal antibody otelixizumab in new-onset type 1 diabetes2020 Diabetologia article Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access cited by 2 patents
Bart Keymeulen, André van Maurik, João Joaquim de Oliveira, Rene J. McLaughlin, Rachel Gittelman, Bart O. Roep, +7 more
51citations -
Survey on fan-beam computed tomography for radiotherapy: Imaging for dose calculation and delineation2023 Physics and Imaging in Radiation Oncology article Physics and Astronomy Advanced Radiotherapy Techniques Open access
Esther Decabooter, Guido C. Hilgers, Joke De Rouck, Koen Salvo, Hilde Bosmans, Brent van der Heyden, +5 more
6citations -
Nature and frequency of prescription modifications in community pharmacies: A nationwide study in the Netherlands2020 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacy and Medical Practices Open access
W Ellen van Loon, Sander Diederik Borgsteede, Gert Baas, Martine Kruijtbosch, Henk Buurma, Peter A. G. M. De Smet, +3 more
12citations -
TEIPP-vaccination in checkpoint-resistant non-small cell lung cancer: a first-in-human phase I/II dose-escalation study2025 Nature Communications article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Mitchell Emmers, Marij J.P. Welters, Michelle V. Dietz, Saskia J A M Santegoets, Sanne Boekesteijn, Anouk Stolk, +12 more
17citations -
FOXG1 dose tunes cell proliferation dynamics in human forebrain progenitor cells2022 Stem Cell Reports article Neuroscience Neurogenesis and neuroplasticity mechanisms Open access cited by 2 patents
Nuwan C. Hettige, Huashan Peng, Hanrong Wu, Xin Zhang, Volodymyr Yerko, Ying Zhang, +14 more
18citations -
Treating socket discharge and discomfort: a crossover randomised trial of vitamin A ointment, low-dose steroid eyedrops and artificial tears2026 British Journal of Ophthalmology article Biochemistry, Genetics and Molecular Biology Ocular Disorders and Treatments Open access
Arthur Yu Xiang Liu, Stijn W. van der Meeren, Adriaan D. Coumou, Rachel Kalmann, Dyonne T. Hartong
0citations -
Randomized Clinical Trial in Older Adult Kidney Transplant Recipients Comparing Everolimus and Reduced-Dose Tacrolimus with Mycophenolate and Tacrolimus Immunosuppression: The OPTIMIZE Study2025 Journal of the American Society of Nephrology article Medicine Renal Transplantation Outcomes and Treatments
Stefan P. Berger, Silke E. de Boer, Jip Jonker, Fréderike J. Bemelman, Michiel G.H. Betjes, Aiko P. J. de Vries, +7 more
0citations -
Safety, reactogenicity, and immunogenicity of a 2-dose Ebola vaccine regimen of Ad26.ZEBOV followed by MVA-BN-Filo in healthy adult pregnant women: study protocol for a phase 3 open-label randomized controlled trial
Etienne Karita, Julien M. Nyombayire, Rosine Ingabire, Amelia Mazzei, Tyronza Sharkey, Jeannine Mukamuyango, +12 more
19citations -
Safety and immunogenicity of 2-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccination in children and adolescents in Africa: A randomised, placebo-controlled, multicentre Phase II clinical trial
Zacchaeus Anywaine, Houreratou Barry, Omu Aggrey Anzala, Gaudensia Nzembi Mutua, Sodiomon Bienvenu Sirima, Serge Paul Eholié, +17 more
65citations -
Safety and immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in infants: a phase 2, randomised, double-blind, active-controlled trial in Guinea and Sierra Leone
Edward Man-Lik Choi, Boris Lacarra, Muhammed Olanrewaju Afolabi, Boni Maxime Ale, Frank Baiden, Christine Bétard, +73 more
18citations -
Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner2020 PLoS Genetics article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Alex N. Zelensky, Mascha Schoonakker, Inger Brandsma, Marcel Tijsterman, Dik C. van Gent, Jeroen Essers, +1 more
11citations -
Population pharmacokinetics of intravenous cefotaxime indicates that higher doses are required for critically ill children2022 Journal of Antimicrobial Chemotherapy article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Stan J. F. Hartman, Parth J. Upadhyay, Ron A. A. Mathôt, Michiel van der Flier, Michiel F. Schreuder, Roger J. M. Brüggemann, +2 more
7citations -
A novel sustained‐release cysteamine bitartrate formulation for the treatment of cystinosis: Pharmacokinetics and safety in healthy male volunteers2021 Pharmacology Research & Perspectives article Medicine Biomedical Research and Pathophysiology Open access
Cécile L. Berends, Lisa Pagan, Michiel Joost van Esdonk, Naomi B. Klarenbeek, Kirsten Riber Bergmann, Matthijs Moerland, +7 more
8citations -
The Use of Phospholipids to Make Pharmaceutical Form Line Extensions2021 European Journal of Lipid Science and Technology article Pharmacology, Toxicology and Pharmaceutics Drug Solubulity and Delivery Systems Open access cited by 2 patents
Peter van Hoogevest, Harry L.G.M. Tiemessen, Josbert M. Metselaar, Simon Drescher, Alfred Fahr
33citations -
Effects of Denosumab in Japanese Patients With Rheumatoid Arthritis Treated With Conventional Antirheumatic Drugs: 36-month Extension of a Phase III Study2021 The Journal of Rheumatology article Medicine Rheumatoid Arthritis Research and Therapies Open access
Yoshiya Tanaka, Tsutomu Takeuchi, Satoshi Soen, Hisashi Yamanaka, Toshiyuki Yoneda, Sakae Tanaka, +4 more
16citations