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Step-in Dosing in the Bosutinib Dose Optimization Study (BODO) Failed to Reduce Gastrointestinal (GI) Toxicity in Patients Failing Second Generation TKI (2G-TKI) in Chronic Phase Chronic Myeloid Leukemia (CML) but Suggests Promising Molecular Response
Susanne Isfort, Dominik Georg Friedrich Wolf, Lino Lars Teichmann, Martina Margrit Crysandt, Andreas Burchert, Andreas Hochhaus, +11 more
5citations -
Revisiting Acyclovir Dosing for Adult Viral Encephalitis Using a Full Bayesian LeiCNS PBPK Modeling Approach2025 Clinical Pharmacokinetics article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Tingjie Guo, Martijn L. Manson, Anne‐Grete Märtson, Jacob Bodilsen, Elizabeth C. M. de Lange
3citations -
Does nonlinear blood-brain barrier transport matter for (lower) morphine dosing strategies?2023 European Journal of Pharmaceutical Sciences article Medicine Pain Management and Opioid Use Open access
Berfin Gülave, Divakar Budda, Mohammed A. A. Saleh, J. G. Coen van Hasselt, Elizabeth C. M. de Lange
4citations -
Does nonlinear blood-brain barrier transport matter for morphine dosing strategies?2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Barrier Structure and Function Studies Open access
Berfin Gülave, Divakar Budda, Mohammed A. A. Saleh, J. G. Coen van Hasselt, Elizabeth C. M. de Lange
0citations -
Real‐world study on fluoropyrimidine‐related toxicity outcomes in cancer patients with select DPYD variant alleles that received DPYD genotype‐guided dosing2025 International Journal of Cancer article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Sofía L. J. Peeters, Didier Meulendijks, Zerina Kadric, Sara Ibrovic, Geert‐Jan Creemers, Vanja Milosevic, +7 more
6citations -
Safety and efficacy of the mutant calreticulin-specific monoclonal antibody INCA033989 as monotherapy or in combination with ruxolitinib in patients (pts) with myelofibrosis (MF): Preliminary results from dose escalation of two global Phase 1 studies
Andrew Charles Perkins, Vincent Ribrag, William E. Shomali, Rosa María Ayala, Claire N. Harrison, Stephen T. Oh, +2 more
12citations -
Dosage, Intensity, and Frequency of Language Therapy for Aphasia : A Systematic Review–Based, Individual Participant Data Network Meta-Analysis2022 Kölner Universitäts PublikationsServer (Universität zu Köln) review Neuroscience Neurobiology of Language and Bilingualism Open access
Myzoon Ali, Kathryn VandenBerg, Linda Jane Williams, Louise R. Williams, Masahiro Abo, Frank Becker, +60 more
96citations -
Efficacy and Safety of Less Frequent/Lower Intensity Dosing of Talquetamab in Patients with Relapsed/Refractory Multiple Myeloma: Results from the Phase 1/2 MonumenTAL-1 Study
Ajai Chari, Albert Oriol, Amrita Y. Krishnan, Maria Del Carmen Martinez Chamorro, Luciano J. Costa, María‐Victoria Mateos, +9 more
50citations -
Attitudes and Practices Regarding Dosing Interval Extension of Biologics in Severe Asthma: A Nationwide Survey and Real-World Data From the Dutch RAPSODI Registry2026 The Journal of Allergy and Clinical Immunology In Practice article Medicine Asthma and respiratory diseases Open access
Camiel J M Marijnissen, Jacob K. Sont, Fleur L. Meulmeester, Michel W.J.M. Wouters, Gert‐Jan Braunstahl, Arnoud F Aldenkamp, +26 more
0citations -
Influence of personalized extended interval dosing on the natalizumab wearing-off effect - a sub-study of the NEXT-MS trial2024 Journal of the Neurological Sciences article Medicine Multiple Sclerosis Research Studies Open access
Alyssa A Toorop, Mark HJ Wessels, Liza M. Y. Gelissen, Elske Hoitsma, E.M.P.E. Zeinstra, Luuk C van Rooij, +24 more
7citations -
A randomised, single-blind, placebo-controlled, dose-finding safety and tolerability study of the anti-CD3 monoclonal antibody otelixizumab in new-onset type 1 diabetes2020 Diabetologia article Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access cited by 2 patents
Bart Keymeulen, André van Maurik, João Joaquim de Oliveira, Rene J. McLaughlin, Rachel Gittelman, Bart O. Roep, +7 more
51citations -
Survey on fan-beam computed tomography for radiotherapy: Imaging for dose calculation and delineation2023 Physics and Imaging in Radiation Oncology article Physics and Astronomy Advanced Radiotherapy Techniques Open access
Esther Decabooter, Guido C. Hilgers, Joke De Rouck, Koen Salvo, Hilde Bosmans, Brent van der Heyden, +5 more
6citations -
Nature and frequency of prescription modifications in community pharmacies: A nationwide study in the Netherlands2020 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacy and Medical Practices Open access
W Ellen van Loon, Sander Diederik Borgsteede, Gert Baas, Martine Kruijtbosch, Henk Buurma, Peter A. G. M. De Smet, +3 more
12citations -
TEIPP-vaccination in checkpoint-resistant non-small cell lung cancer: a first-in-human phase I/II dose-escalation study2025 Nature Communications article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Mitchell Emmers, Marij J.P. Welters, Michelle V. Dietz, Saskia J A M Santegoets, Sanne Boekesteijn, Anouk Stolk, +12 more
17citations -
FOXG1 dose tunes cell proliferation dynamics in human forebrain progenitor cells2022 Stem Cell Reports article Neuroscience Neurogenesis and neuroplasticity mechanisms Open access cited by 2 patents
Nuwan C. Hettige, Huashan Peng, Hanrong Wu, Xin Zhang, Volodymyr Yerko, Ying Zhang, +14 more
18citations -
Treating socket discharge and discomfort: a crossover randomised trial of vitamin A ointment, low-dose steroid eyedrops and artificial tears2026 British Journal of Ophthalmology article Biochemistry, Genetics and Molecular Biology Ocular Disorders and Treatments Open access
Arthur Yu Xiang Liu, Stijn W. van der Meeren, Adriaan D. Coumou, Rachel Kalmann, Dyonne T. Hartong
0citations -
Randomized Clinical Trial in Older Adult Kidney Transplant Recipients Comparing Everolimus and Reduced-Dose Tacrolimus with Mycophenolate and Tacrolimus Immunosuppression: The OPTIMIZE Study2025 Journal of the American Society of Nephrology article Medicine Renal Transplantation Outcomes and Treatments
Stefan P. Berger, Silke E. de Boer, Jip Jonker, Fréderike J. Bemelman, Michiel G.H. Betjes, Aiko P. J. de Vries, +7 more
0citations -
Safety, reactogenicity, and immunogenicity of a 2-dose Ebola vaccine regimen of Ad26.ZEBOV followed by MVA-BN-Filo in healthy adult pregnant women: study protocol for a phase 3 open-label randomized controlled trial
Etienne Karita, Julien M. Nyombayire, Rosine Ingabire, Amelia Mazzei, Tyronza Sharkey, Jeannine Mukamuyango, +12 more
19citations -
Safety and immunogenicity of 2-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccination in children and adolescents in Africa: A randomised, placebo-controlled, multicentre Phase II clinical trial
Zacchaeus Anywaine, Houreratou Barry, Omu Aggrey Anzala, Gaudensia Nzembi Mutua, Sodiomon Bienvenu Sirima, Serge Paul Eholié, +17 more
65citations -
Safety and immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in infants: a phase 2, randomised, double-blind, active-controlled trial in Guinea and Sierra Leone
Edward Man-Lik Choi, Boris Lacarra, Muhammed Olanrewaju Afolabi, Boni Maxime Ale, Frank Baiden, Christine Bétard, +73 more
18citations