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Association of Polymorphic Cytochrome P450 Enzyme Pathways with Falls in Multimedicated Older Adults2024 Journal of the American Medical Directors Association article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Katja Susanne Just, Laura M. Pott, Catharina Scholl, Michael Steffens, Michael Dieter Denkinger, Dietrich Rothenbacher, +2 more
4citations -
Nanoscopic visualization of microgel-immobilized cytochrome P450 enzymes and their local activity2024 Nanoscale article Engineering Innovative Microfluidic and Catalytic Techniques Innovation Open access
Lukas Schubert, Chiara Nenninger, Maximilian Nöth, Thomke Belthle, Robert Dirk de Lange, Andrij Pich, +2 more
3citations -
MicroGelzymes: pH-Independent Immobilization of Cytochrome P450 BM3 in Microgels2020 Biomacromolecules article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization
Maximilian Nöth, Larissa Hussmann, Thomke Belthle, Islam El‐Awaad, Mehdi D. Davari, Felix Jakob, +2 more
38citations -
Flexibility Regulation of Loops Surrounding the Tunnel Entrance in Cytochrome P450 Enhanced Substrate Access Substantially2022 ACS Catalysis article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization
Zhongyu Li, Shuaiqi Meng, Kaili Nie, Ulrich Schwaneberg, Mehdi D. Davari, Haijun Xu, +2 more
80citations -
Preparative‐Scale Production of Testosterone Metabolites by Human Liver Cytochrome P450 Enzyme 3A42020 Advanced Synthesis & Catalysis article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Nico D. Fessner, Matic Srdič, Hansjörg Weber, Christian Schmid, David Schönauer, Ulrich Schwaneberg, +1 more
20citations -
Preparative Production of Functionalized (N- and O-Heterocyclic) Polycyclic Aromatic Hydrocarbons by Human Cytochrome P450 3A4 in a Bioreactor2022 Biomolecules article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Matic Srdič, Nico D. Fessner, Deniz Yıldız, Anton Glieder, Markus Spiertz, Ulrich Schwaneberg
7citations -
Uncoupling of Cytochrome P450 2B6 and stimulation of reactive oxygen species production in pharmacogenomic alleles affected by interethnic variability2024 Biochimica et Biophysica Acta (BBA) - General Subjects article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Sabrina Yamoune, Julian Peter Müller, Immaculate Mbongo Langmia, Catharina Scholl, Julia Stingl
10citations -
Assessment of Substrate Status of Drugs Metabolized by Polymorphic Cytochrome P450 (CYP) 2 Enzymes: An Analysis of a Large-Scale Dataset2024 Biomedicines article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Justyna Wozniak, Judith Schmitt, Jana Koch, Julia Stingl, Katja Susanne Just
6citations -
Impact of steroid hormone levels on estradiol‐mediated regulation of cytochrome P450 2B6 compared to 1B1 in breast cancer cells2024 Basic & Clinical Pharmacology & Toxicology article Biochemistry, Genetics and Molecular Biology Estrogen and related hormone effects Open access
Marco Hoffmann, Julian Peter Müller, Jochen Maurer, A. Folliot, Sabrina Yamoune, Julia Stingl
5citations -
Structural insights into the effects of glycerol on ligand binding to cytochrome P4502022 Acta Crystallographica Section D Structural Biology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism
Sergey S. Bukhdruker, Tatsiana Varaksa, Philipp S. Orekhov, Irina P. Grabovec, Egor Marin, Ivan Kapranov, +10 more
4citations -
Role of cytochrome P450 2C8 genetic polymorphism and epoxygenase uncoupling in periodontal remodelling affecting orthodontic treatment2021 Basic & Clinical Pharmacology & Toxicology article Medicine Bone health and treatments Open access
Sabrina Yamoune, Katharina Wintz, Christian Niederau, Rogerio Bastos Craveiro, Michael F. Wolf, Julia Stingl
7citations -
Evaluation of stabilizing additives to protect activities of cytochrome P450 enzymes for in vitro drug testing and pharmacogenetic studies: Focus on CYP2D62025 Biochimica et Biophysica Acta (BBA) - General Subjects article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism
Sabrina Yamoune, Henner Koch, Daniel Delev, Yvonne G. Weber, Julia Stingl
4citations -
Insights on intermolecular FMN-heme domain interaction and the role of linker length in cytochrome P450cin fusion proteins2020 Biological Chemistry article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism
Ketaki D. Belsare, Anna Joëlle Ruff, Ronny Martínez, Ulrich Schwaneberg
3citations -
A Screening Method for P450 BM3 Mutant Libraries Using Multiplexed Capillary Electrophoresis for Detection of Enzymatically Converted Compounds2022 Methods in molecular biology book-chapter Engineering Microfluidic and Capillary Electrophoresis Applications
Anna Gärtner, Gustavo de Almeida Santos, Anna Joëlle Ruff, Ulrich Schwaneberg
2citations -
Modulating the Coupling Efficiency of P450 BM3 by Controlling Water Diffusion through Access Tunnel Engineering2021 ChemSusChem article Engineering Innovative Microfluidic and Catalytic Techniques Innovation Open access cited by 1 patent
Shuaiqi Meng, Yu Ji, Luo Liu, Mehdi D. Davari, Ulrich Schwaneberg
24citations -
Structural insights into 3Fe–4S ferredoxins diversity in M. tuberculosis highlighted by a first redox complex with P4502023 Frontiers in Molecular Biosciences article Energy Metalloenzymes and iron-sulfur proteins Open access
Andrei A. Gilep, Tatsiana Varaksa, Sergey S. Bukhdruker, Anton Kavaleuski, Yury L. Ryzhykau, Sviatlana V. Smolskaya, +17 more
13citations -
Dataset to "A hydroquinone-specific screening system for directed P450 evolution"2020 RWTH Publications (RWTH Aachen) dataset Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access
Alexandra Maria Weingartner, Anna Joëlle Ruff, Ulrich Schwaneberg, Daniel F. Sauer, Gaurao V. Dhoke
0citations -
The molecular basis and enzyme engineering strategies for improvement of coupling efficiency in cytochrome P450s2022 Biotechnology Advances article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism
Shuaiqi Meng, Yu Ji, Leilei Zhu, Gaurao V. Dhoke, Mehdi D. Davari, Ulrich Schwaneberg
49citations -
Introduction of aromatic amino acids in electron transfer pathways yielded improved catalytic performance of cytochrome P450s2023 CHINESE JOURNAL OF CATALYSIS (CHINESE VERSION) article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism
Shuaiqi Meng, Zhongyu Li, Yu Ji, Anna Joëlle Ruff, Luo Liu, Mehdi D. Davari, +1 more
39citations -
Engineered P450 BM3 and cpADH5 coupled cascade reaction for β-oxo fatty acid methyl ester production in whole cells2020 Enzyme and Microbial Technology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism
Yunus Ensari, Gustavo de Almeida Santos, Anna Joëlle Ruff, Ulrich Schwaneberg
11citations