Papers matching “constraint-based modeling” 28
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Processed transcriptomic dataset of human iPSC-derived dopaminergic neurons for constraint-based metabolic modeling0citations
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Constraint-based modeling of bioenergetic differences between synaptic and non-synaptic components of dopaminergic neurons in Parkinson’s disease2025 Frontiers in Computational Neuroscience article Medicine Parkinson's Disease Mechanisms and Treatments Open access
Xi Luo, Diana Charles El Assal, Yanjun Liu, Samira Ranjbar, Ronan M. T. Fleming
3citations -
Cardinality optimization in constraint-based modelling: application to human metabolism2023 Bioinformatics article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Ronan M. T. Fleming, Hulda S. Haraldsdóttir, Phan Tu Vuong, Thomas Hankemeier, Ines Thiele
10citations -
Constraint-based modelling of metabolic dysregulation in Gaucher disease: mitochondrial dysfunction and disrupted cholesterol homeostasis2026 Orphanet Journal of Rare Diseases article Medicine Lysosomal Storage Disorders Research Open access
Yanjun Liu, Xi Luo, Samira Ranjbar, Johannes M. F. G. Aerts, Martijn van der Lienden, Andrea Dardis, +1 more
2citations -
Mechanistic model-driven exometabolomic characterisation of human dopaminergic neuronal metabolism2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
German Preciat, Agnieszka B. Wegrzyn, Edinson Lucumi Moreno, Cornelius C.W. Willacey, Jennifer Modamio, Fátima Liliana Monteiro, +18 more
12citations -
FROG Analysis Ensures the Reproducibility of Genome Scale Metabolic Models2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Karthik Raman, Miroslav Kratochvíl, Brett G. Olivier, Matthias König, Pratyay Sengupta, Dinesh Kumar Kuppa Baskaran, +85 more
11citations -
XomicsToModel: Omics data integration and generation of thermodynamically consistent metabolic models2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
German Preciat, Agnieszka B. Wegrzyn, Ines Thiele, Thomas Hankemeier, Ronan M. T. Fleming
10citations -
XomicsToModel: omics data integration and generation of thermodynamically consistent metabolic models2025 Nature Protocols article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
German Preciat, Agnieszka B. Wegrzyn, Xi Luo, Ines Thiele, Thomas Hankemeier, Ronan M. T. Fleming
5citations -
Conserved moiety fluxomics2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Ronan M. T. Fleming, Hulda S. Haraldsdóttir, German Preciat, Luojiao Huang, Ines Thiele, Amy C. Harms, +1 more
3citations -
Analysis across scales: Integrated insights in metabolism and economic feasibility of recombinant protein production from CO2 and H20citations
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Analysis across scales: Integrated insights in metabolism and economic feasibility of recombinant protein production from CO2 and H20citations