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COMPOSER Part 4: An Optimized Dosing Strategy for Crovalimab in the Treatment of Complement Inhibitor-Naïve or -Experienced Patients with Paroxysmal Nocturnal Hemoglobinuria
Régis Peffault de Latour, Simona Sica, Julia G. Ramos, Jules Hernández‐Sánchez, Jin Seok Kim, Anna Kiialainen, +11 more
3citations -
The role of complement activation in autoimmune liver disease2020 Autoimmunity Reviews article Medicine Liver Diseases and Immunity Open access cited by 1 patent
Maaike Biewenga, Arantza Fariña Sarasqueta, Maarten E. Tushuizen, Eveline S. M. de Jonge‐Muller, Bart van Hoek, Leendert Adrianus Trouw
35citations -
Targeted donor complement blockade after brain death prevents delayed graft function in a nonhuman primate model of kidney transplantation2020 American Journal of Transplantation article Medicine Renal Transplantation Outcomes and Treatments Open access cited by 1 patent
Juan Sebastian Danobeitia, Tiffany J. Zens, Peter J. Chlebeck, Laura Jo Zitur, José Antonio Muñoz Reyes, Michael J. Eerhart, +16 more
31citations -
Abstract 4544: Multifaceted mechanism of action of DuoHexaBody-CD37 involves both complement- and Fc gamma receptor-mediated cytotoxicity in pre-clinical B-cell lymphoma models
Laurens P. Kil, Simone C. Oostindie, Kristin Strumane, Hilma J. van der Horst, Berris van Kessel, Marije B. Overdijk, +12 more
0citations -
Complement Receptor Targeted Liposomes Encapsulating the Liver X Receptor Agonist GW3965 Accumulate in and Stabilize Atherosclerotic Plaques2020 Advanced Healthcare Materials article Materials Science Nanoparticle-Based Drug Delivery Open access
Naomi Benne, Renata Martins Cardoso, Aimee L. Boyle, Alexander Kros, Wim Jiskoot, Johan Kuiper, +3 more
22citations -
One‐year outcomes from a phase 3 randomized trial of ravulizumab in adults with paroxysmal nocturnal hemoglobinuria who received prior eculizumab2020 European Journal Of Haematology article Immunology and Microbiology Complement system in diseases Open access
Austin Gladston Kulasekararaj, Anita Hill, Saskia M. C. Langemeijer, Richard A. Wells, Fernando Ataúlfo González Fernández, Anna Gayà, +12 more
36citations -
RESULTS OF THE PEGASUS PHASE 3 RANDOMIZED TRIAL DEMONSTRATING SUPERIORITY OF THE C3 INHIBITOR PEGCETACOPLAN COMPARED TO ECULIZUMAB IN PATIENTS WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA2020 Hematology Transfusion and Cell Therapy article Immunology and Microbiology Complement system in diseases Open access
Peter Hillmen, Jeff Szer, Britta Höchsmann, Jens Panse, Jean‐Jacques Kiladjian, Carlos M. DeCastro, +7 more
3citations -
An Optimized Crovalimab Dose and Regimen Reduced the Formation of Drug-Target-Drug Complexes in Patients with Paroxysmal Nocturnal Hemoglobinuria from the Phase I/II COMPOSER Trial
Jun‐ichi Nishimura, Antoine Soubret, Simon Buatois, Jean‐Eric Charoin, Sasha Sreckovic, Christoph Marcus Bucher, +21 more
3citations -
Mono-ADP-ribosylation by ARTD10 restricts Chikungunya virus replication by interfering with the proteolytic activity of nsP22020 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology interferon and immune responses Open access
Sarah Krieg, Fabian Pott, Laura Eckei, Maud Verheirstraeten, Mareike Bütepage, Barbara E. Lippok, +3 more
10citations -
Evolutionary and Functional Analysis of a Chara Plasma Membrane H+-ATPase2020 Frontiers in Plant Science article Biochemistry, Genetics and Molecular Biology ATP Synthase and ATPases Research Open access
Suyun Zhang, Myckel E. J. Habets, Holger Breuninger, Liam Dolan, Remko Offringa, Bert van Duijn
11citations
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