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Successful pharmacological intervention at different levels of the complement system in an in vitro complement fixation model for bullous pemphigoid
Jenny Giang, Martijn B. A. van Doorn, Gilles F.H. Diercks, Santiago Rodrı́guez de Córdoba, Thierry P. P. van den Bosch, Marco W.J. Schreurs, +2 more
3citations -
Moss-produced human complement factor H with modified glycans has an extended half-life and improved biological activity2024 Frontiers in Immunology article Immunology and Microbiology Complement system in diseases Open access cited by 2 patents
Todor Tschongov, Swagata Konwar, Andreas E Busch, Christian Sievert, Andrea Hartmann, Marina Noris, +7 more
16citations -
Selective Binding of Heparin/Heparan Sulfate Oligosaccharides to Factor H and Factor H-Related Proteins: Therapeutic Potential for C3 Glomerulopathies2021 Frontiers in Immunology article Immunology and Microbiology Complement system in diseases Open access
Markus A. Loeven, Marissa L. Maciej-Hulme, Cansu Yanginlar, Melanie C. Hubers, Edwin R. Kellenbach, Mark de Graaf, +5 more
21citations -
Pivotal clinical trials in C3 glomerulopathy: answers and remaining uncertainties2026 Nephrology Dialysis Transplantation article Immunology and Microbiology Complement system in diseases Open access
Fernando Caravaca‐Fontán, Annette N. Bruchfeld, Sarah Margaret Moran, Stefanie Steiger, Kate Stevens, Y K Onno Teng, +4 more
0citations -
Medical Records-Based Genetic Studies of the Complement System2021 Journal of the American Society of Nephrology article Immunology and Microbiology Complement system in diseases Open access
Atlas Khan, Ning Shang, Lynn Petukhova, Jun Zhang, Yufeng Shen, Scott Joseph Hebbring, +15 more
16citations -
Management of recurrent C3 glomerulopathy after kidney transplantation2026 Nephrology Dialysis Transplantation article Immunology and Microbiology Complement system in diseases Open access
Hernando Trujillo, Teresa Cavero, Sarah Margaret Moran, Şafak Mirioğlu, Annette N. Bruchfeld, Stefanie Steiger, +7 more
0citations -
#3018 Iptacopan's rapid and sustained inhibition of overactive complement alternative pathway in C3G: Exploratory analysis from the Phase 3 APPEAR-C3G study2025 Nephrology Dialysis Transplantation article Immunology and Microbiology Complement system in diseases Open access
Erica Daina, Giuseppe Remuzzi, David Kavanagh, Imelda Schuhmann, Rubeen Israni, Hari Varun Kalluri, +4 more
0citations -
Elevated Plasma Complement Factors in CRB1 -Associated Inherited Retinal Dystrophies2025 Investigative Ophthalmology & Visual Science article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Lude Moekotte, Joke Helena de Boer, Sanne Hiddingh, Aafke de Ligt, Xuan‐Thanh‐An Nguyen, Carel B. Hoyng, +28 more
3citations -
Association of Urinary Complement Peptides with Kidney Function and Progression of Kidney Disease2026 International Journal of Molecular Sciences article Immunology and Microbiology Complement system in diseases Open access
Thi Minh Nghia Nguyen, Margarita Kondyli, Harald Mischak, Felix Keller, Joachim Beige, Agnieszka Latosińska, +1 more
0citations -
Thrombospondin-1 inhibits alternative complement pathway activation in antineutrophil cytoplasmic antibody-associated vasculitis2025 Journal of Clinical Investigation article Immunology and Microbiology Complement system in diseases Open access
Swagata Konwar, Sophie Schroda, Manuel Rogg, Jessika Kleindienst, Eva L. Decker, Martin Pöhl, +9 more
8citations -
Factor H‐related protein 1: a complement regulatory protein and guardian of necrotic‐type surfaces2020 British Journal of Pharmacology article Immunology and Microbiology Complement system in diseases Open access cited by 3 patents
Christine Skerka, Gabriele Pradel, Luke D. Halder, Peter F. Zipfel, Svante L. H. Zipfel, Olaf Strauß
24citations -
Inhibition of complement activation by CD55 overexpression in human induced pluripotent stem cell derived kidney organoids2023 Frontiers in Immunology article Immunology and Microbiology Complement system in diseases Open access
Lonneke H. Gaykema, Rianne Y. van Nieuwland, Mette C. Dekkers, Mieke F. van Essen, Sebastiaan Heidt, Arnaud Zaldumbide, +3 more
17citations -
Brain death-induced lung injury is complement dependent, with a primary role for the classical/lectin pathway2020 American Journal of Transplantation article Immunology and Microbiology Complement system in diseases Open access
Judith E. van Zanden, Neeltina M. Jager, Marc A. Seelen, Mohamed R. Daha, Zwanida J. Veldhuis, Henri G. D. Leuvenink, +1 more
7citations -
Inhibition of complement factor C5a or C5aR for cholesterol crystal embolism–related vascular thrombosis with microvascular injury and its consequences2024 Kidney International article Immunology and Microbiology Complement system in diseases Open access cited by 1 patent
Chao Han, Elmina Mammadova‐Bach, Kanako Watanabe‐Kusunoki, Tâmisa Seeko Bandeira Honda, Yihong Li, Chenyu Li, +16 more
13citations -
RESULTS OF THE PEGASUS PHASE 3 RANDOMIZED TRIAL DEMONSTRATING SUPERIORITY OF THE C3 INHIBITOR PEGCETACOPLAN COMPARED TO ECULIZUMAB IN PATIENTS WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA2020 Hematology Transfusion and Cell Therapy article Immunology and Microbiology Complement system in diseases Open access
Peter Hillmen, Jeff Szer, Britta Höchsmann, Jens Panse, Jean‐Jacques Kiladjian, Carlos M. DeCastro, +7 more
3citations -
WCN26-5461 ORAL IPTACOPAN THERAPY IN C3 GLOMERULOPATHY SHOWS CONSISTENT STABILIZATION OF eGFR SLOPE ACROSS PATIENT SUBGROUPS2026 Kidney International Reports article Immunology and Microbiology Complement system in diseases Open access
Andrew S. Bomback, Carla Nester, Richard J.H. Smith, Liz Lightstone, Marina Vivarelli, Sophie Chauvet, +7 more
0citations -
P774: SUBSTANTIAL INCREASES IN PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) RED BLOOD CELL CLONE SIZE WITH ORAL IPTACOPAN MONOTHERAPY CONFIRMS CONTROL OF HEMOLYSIS IN COMPLEMENT INHIBITOR-NAÏVE PNH PATIENTS
Régis Peffault de Latour, Bing Han, Jaroslaw Pawel Maciejewski, Yutaka Ueda, Rong Fu, Li Zhang, +15 more
3citations -
The bending of C3: Experimentally probing the l -type doubling and resonance2022 Journal of Molecular Spectroscopy article Chemistry Molecular Spectroscopy and Structure Open access
Marie‐Aline Martin‐Drumel, Qiang Zhang, Kirstin D. Doney, Olivier Pirali, M. Vervloët, Dennis W. Tokaryk, +4 more
7citations -
Circulating levels of endogenous complement inhibitors correlate inversely with complement consumption in systemic lupus erythematosus2024 European Journal of Immunology article Medicine Systemic Lupus Erythematosus Research Open access
Stef van der Meulen, Rory Caitlin Monahan, Kyra A. Gelderman, Cees van Kooten, Y K Onno Teng, Tom W. J. Huizinga, +2 more
3citations