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Analysis of the H-Ras mobility pattern in vivo shows cellular heterogeneity inside epidermal tissue2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Advanced Fluorescence Microscopy Techniques Open access
Radoslaw J. Gora, Babette de Jong, Patrick van Hage, Mary Ann Rhiemus, Fjodor van Steenis, John van Noort, +2 more
1citations -
Single Cell Raman and Mass Spectrometry Analysis to Probe Cellular Heterogeneity in Tamoxifen Uptake, Metabolism and Effect2025 SSRN Electronic Journal preprint Biochemistry, Genetics and Molecular Biology Spectroscopy Techniques in Biomedical and Chemical Research Open access
Congrou Zhang, Yasmine Abouleila, Sylvia E. Le Dévédec, Thomas Hankemeier, Arno Germond
0citations -
Single-myofiber RNA-sequencing reveals myofiber-level transcriptomic heterogeneity and DUX4 activation in FSHD muscle biopsies2025 Research Square preprint Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Silvère M. van der Maarel, Anita van den Heuvel, Dongxu Zheng, Svetlana Pasteuning-Vuhman, Joke W. Boertje-van der Meulen, Emile de Meijer, +2 more
0citations -
Multimodal analysis unveils tumor microenvironment heterogeneity linked to immune activity and evasion2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Óscar Lapuente-Santana, Gregor Sturm, Markus Außerhofer, Constantin Zackl, Maria Zopoglou, Nicholas McGranahan, +5 more
0citations -
Spatiotemporal heterogeneity of glioblastoma is dictated by microenvironmental interference2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Glioma Diagnosis and Treatment Open access
Vidhya Madapusi Ravi, Paulina Will, Jan Kueckelhaus, Na Sun, Kevin Joseph, Henrike Salié, +20 more
12citations -
Characterization of the continuous transcriptional heterogeneity in Wilms’ tumors using unsupervised machine learning2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Renal and related cancers Open access
Yaron Trink, Achia Urbach, Benjamin Dekel, Peter Hohenstein, Jacob Goldberger, Tomer Kalisky
1citations -
Cyst-type epithelial heterogeneity shapes therapeutic responsiveness in ADPKD2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases Open access
Johannes Roeles, Axel Giesler, Jessica Schmitz, Johannes Koenig, Frank Friedersdorff, Jonas Busch, +18 more
0citations -
Interindividual HLA Evolutionary Divergence in Single HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation for Malignant Hematological Disorders: A Report on Behalf of the Cellular Therapy and Immunobiology Working Party of the EBMT
Simona Pagliuca, Jarl Mooyaart, Francis Ayuketang Ayuk, Robert Zeiser, Victoria T. Potter, Peter Dreger, +23 more
0citations -
GraphHDBSCAN*: Graph-based Hierarchical Clustering on High Dimensional Single-cell RNA Sequencing Data2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Seyed Ardalan Ghoreishi, Aleksandra Szmigiel, James Shiniti Nagai, Ivan G. Costa, Arthur Zimek, Ricardo J. G. B. Campello
1citations -
Latent plasticity of the human pancreas across development, health, and disease2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Pancreatic function and diabetes Open access
Elisabetta Mereu, Diego Balboa, Johannes Liebig, A. Herrero, Anna Martinez Casals, Mariya Mardamshina, +37 more
5citations -
Synthesis of Cyclopropene-Modified Fatty Acids Allows Single Cell Quantification of Uptake By Immune Cells2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Chemistry Click Chemistry and Applications Open access
Luuk Reinalda, Graham A. Heieis, Marouane el Boujadayni, Kas Steuten, Kristine Bertheussen, Laura Bogue Edgerton, +5 more
0citations -
Polyploid cardiomyocytes define disease-specific transcriptional states in the mammalian heart2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Paul Kießling, Mehdi Joodaki, Daryna Pikulska, Emilia Scheidereit, Giulia Cesaro, Mayra Ruiz, +52 more
5citations -
Human Neocortical Glutamatergic Neurons Revealed Through Multimodal Profiling2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Rachel A. Dalley, Sarah Walling-Bell, Jeremy A. Miller, Femke Waleboer, Julian Thijssen, Audrey McCutcheon, +88 more
3citations -
Population-level comparisons of gene regulatory networks modeled on high-throughput single-cell transcriptomics data2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Daniel Osorio, Anna Capasso, S. Gail Eckhardt, Uma P. Giri, Alexander J. Somma, Todd M. Pitts, +8 more
2citations -
Mapping the glial transcriptome in Huntington’s disease using snRNAseq: Selective disruption of glial signatures across brain regions2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Genetic Neurodegenerative Diseases Open access
Sunniva M. K. Bøstrand, Luise A. Seeker, Nina-Lydia Kazakou, Nadine Bestard-Cuche, Sarah Jäkel, Boyd Kenkhuis, +5 more
1citations -
Non-operable glioblastoma: proposition of patient-specific forecasting by image-informed poromechanical model2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Mathematics Mathematical Biology Tumor Growth Open access
Stéphane Urcun, Davide Baroli, Pierre‐Yves Rohan, Wafa Skalli, V. Lubrano, Stéphane Bordas, +1 more
1citations -
Novel kinome profiling technology reveals drug treatment is patient and 2D/3D model dependent in GBM2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Glioma Diagnosis and Treatment Open access
Federica Fabro, Nynke M. Kannegieter, Erik L. de Graaf, Karla C. S. Queiroz, Martine L.M. Lamfers, Anna Ressa, +1 more
0citations -
Combinatorial multimer staining and spectral flow cytometry facilitate quantification and characterization of polysaccharide-specific B cell immunity2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Dennis Hoving, A.H.C. Marques, Wesley Huisman, Beckley A. Nosoh, Alicia C. de Kroon, Oscar R. J. van Hengel, +8 more
0citations -
Single-cell characterization of human periodontal ligament (PDL) cells reveals uniformly mesenchymal populations in matched maxilla and mandible pairs from four donors2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Periodontal Regeneration and Treatments Open access
Chloé Radermacher, Robert Dzhanaev, Christian Hasberg, Sabine Neuß-Stein, Andrea Gorgels, Julia Moellmann, +8 more
0citations