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299 3D in vitro tumor microenvironment models for screening CAR-T cell therapy efficacy2022 Regular and Young Investigator Award Abstracts conference-abstract Medicine CAR-T cell therapy research Open access
Sophie Vermond, Ulrike Herbrand, Gemma Moiset, Kolin C. Hribar, Julia B. Schüler
1citations -
T-cell dysfunction in the glioblastoma microenvironment is mediated by myeloid cells releasing interleukin-102022 Nature Communications article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Vidhya Madapusi Ravi, Nicolas Noel Neidert, Paulina Will, Kevin Joseph, Julian P. Maier, Jan Kückelhaus, +22 more
371citations -
Batch-effect correction improves downstream imaging mass cytometry data quality and facilitates robust cell type identification in the liver and hepatocellular carcinoma microenvironment2025 Zeitschrift für Gastroenterologie conference-paper Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics
Henrike Salié, Ana Marta Sequeira, Marieke E. Ijsselsteijn, Felix Röttele, Yuan Suo, Lara Wischer, +4 more
0citations -
Abstract 7196: Detection of radiopharmaceuticals and their cold surrogates by Imaging Mass Cytometry enables assessment of single-cell functional response, therapeutic biodistribution, and modulation of the immune microenvironment
Jennifer L. Gorman, Felix B. Salazar, Kevin Wyszatko, Michael J. Geuenich, Thom G. A. Reuvers, Daniel Majonis, +14 more
0citations -
Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment2024 Cancer Research article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Dominik Schmidt, Cornelia Endres, Rouven Hoefflin, Geoffroy Andrieux, Melissa Zwick, Nikolaos Karantzelis, +23 more
23citations -
Tissue microenvironment dictates the state of human induced pluripotent stem cell-derived endothelial cells of distinct developmental origin in 3D cardiac microtissues2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Xu Cao, Maria Mircea, Francijna E. van den Hil, Hailiang Mei, Katrin Neumann, Konstantinos Anastassiadis, +3 more
1citations -
Beta-Cell-Derived Extracellular Vesicles: Mediators of Intercellular Communication in the Islet Microenvironment in Type 1 Diabetes2024 Cells article Biochemistry, Genetics and Molecular Biology Extracellular vesicles in disease Open access
Mette C. Dekkers, Xudong Pu, Agustin Enciso‐Martinez, Arnaud Zaldumbide
12citations -
Combining Mass Cytometry Data by CyTOFmerge Reveals Additional Cell Phenotypes in the Heterogeneous Ovarian Cancer Tumor Microenvironment: A Pilot Study
Liv Cecilie Vestrheim Thomsen, Katrin Kleinmanns, Shamundeeswari Anandan, Stein‐Erik Gullaksen, Tamim Abdelaal, Grete Alrek Iversen, +3 more
3citations -
Myeloid Cell – T Cell Interactions are Prominent in Pregnancies with Extreme Fetal-Maternal HLA Incompatibility and an Immune Tolerant Microenvironment2025 Journal of Reproductive Immunology article Immunology and Microbiology Reproductive System and Pregnancy Open access
Xuezi Tian, Juliette Krop, Marieke E. Ijsselsteijn, Hanneke Kapsenberg, Jacqueline D.H. Anholts, Lotte E. van der Meeren, +8 more
0citations -
Spatial immune profiling characterizes tumor microenvironment heterogeneity between metastatic and nonmetastatic cutaneous squamous cell carcinoma in organ transplant patients2026 Journal of Investigative Dermatology article Medicine Nonmelanoma Skin Cancer Studies Open access
Veerle A. Merkus, M. Ijsselsteijn, Estella de Jong, Cornelis P. Tensen, A. El Ghalbzouri, Ferenc A. Scheeren, +4 more
0citations