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The Dynamics of Personality Approach (DPA): 20 Tenets for Uncovering the Causal Mechanisms of Personality2020 European Journal of Personality article Psychology Personality Traits and Psychology Open access
Markus Quirin, Michael D. Robinson, John F. Rauthmann, Julius Kühl, Stephen John Read, Mattie Tops, +1 more
63citations -
Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis2022 Nature Genetics article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Kazuyoshi Ishigaki, Saori Sakaue, Chikashi C. Terao, Yang Luo, Kyuto Sonehara, Kensuke Yamaguchi, +84 more
374citations -
Acute ischemic stroke or TIA despite DOAC treatment: the contribution of DOAC plasma levels to understand pathophysiological mechanisms2026 Therapeutic Advances in Neurological Disorders article Medicine Atrial Fibrillation Management and Outcomes Open access
Marcus Immanuel Rust, Merve Gözalan, Omid Nikoubashman, Martin Wiesmann, Matthias Imöhl, Jörg Bernhard Schulz, +2 more
0citations -
Patient-specific models link neurotransmitter receptor mechanisms with motor and visuospatial axes of Parkinson’s disease2023 Nature Communications article Medicine Parkinson's Disease Mechanisms and Treatments Open access
Ahmed Faraz Khan, Quadri Adewale, Sue‐Jin Lin, Tobias R. Baumeister, Yashar Zeighami, Félix Carbonell, +2 more
29citations -
Mechanisms of Melanoma Progression and Treatment Resistance: Role of Cancer Stem-like Cells2024 Cancers article Biochemistry, Genetics and Molecular Biology Melanoma and MAPK Pathways Open access
Youssef Al Hmada, Robert Thomas Brodell, Naji Kharouf, Thomas Wayne Flanagan, Abdulhadi A. AlAmodi, Sofie-Yasmin Hassan, +6 more
40citations -
Mendelian Randomization Analysis of the IL-1 Cytokine Family Proteins Identifies IL1RL1 as a Potential Causal Contributor to Traumatic Brain Injury Prognosis2026 Neurocritical Care article Medicine Traumatic Brain Injury and Neurovascular Disturbances Open access
Youngjune Bhak, Adel E Helmy, Edward Needham, David Krishna Menon, Varun Warrier, Romit J. Samanta, +91 more
0citations -
Assessing youth's internal and external attributions to negative peer interactions and victimization—development of the Causal Attributions for Peer Experiences ( CAPE ) scale2025 Journal of Research on Adolescence article Psychology Bullying, Victimization, and Aggression Open access
Hannah Katharina Peetz, Tessa A. M. Lansu, Nathalie A. H. Hoekstra, Yvonne H. M. van den Berg, William J. Burk, Tim Mainhard
2citations -
Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference2020 Genome biology article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access cited by 1 patent
Paul J. Hop, René Luijk, Lucia Daxinger, Maarten van Iterson, Koen F. Dekkers, Rick Jansen, +40 more
41citations -
Discovery of Hydroxybenzothiazole Urea Compounds as Multitargeted Agents Suppressing Major Cytotoxic Mechanisms in Neurodegenerative Diseases2021 ACS Chemical Neuroscience article Medicine Alzheimer's disease research and treatments cited by 1 patent
Youssef Aboushady, Moustafa Tarek Gabr, Ahmed K. ElHady, Mohamed Salah, Alireza Abadi, Gerrit Wilms, +3 more
9citations -
Contextualization of causal regulatory networks from toxicogenomics data applied to drug-induced liver injury2021 Toxicology Letters article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Panuwat Trairatphisan, Terezinha Maria de Souza, Jos C. S. Kleinjans, Danyel G. J. Jennen, Julio Sáez-Rodríguez
4citations -
Circulating Rhythmic Metabolites and Causal Risk of Type 2 Diabetes in Adults in the Canadian Longitudinal Study on Aging2026 Diabetes Obesity and Metabolism article Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access
Divya Joshi, Talha Rafiq, Marie Pigeyre, Renée de Mutsert, Femke Rutters, Jean‐Pierre Després, +4 more
0citations -
A network-based transcriptomic landscape of HepG2 cells uncovering causal gene-cytotoxicity interactions underlying drug-induced liver injury2023 Toxicological Sciences article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Lukas S. Wijaya, Attila Gábor, Iris Pot, Luca van de Have, Julio Sáez-Rodríguez, James L. Stevens, +3 more
13citations