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From Biological Mechanisms to Causal Inference: Quantitative Systems Pharmacology and Causal Frameworks in Drug Development2026 Clinical Pharmacology & Therapeutics review Mathematics Statistical Methods in Clinical Trials Open access
Thomas Klabunde, Ramon Hernandez Vecino, Piet H. van der Graaf, Tommaso Andreani
0citations -
The Dynamics of Personality Approach (DPA): 20 Tenets for Uncovering the Causal Mechanisms of Personality2020 European Journal of Personality article Psychology Personality Traits and Psychology Open access
Markus Quirin, Michael D. Robinson, John F. Rauthmann, Julius Kühl, Stephen John Read, Mattie Tops, +1 more
63citations -
A Network-based Transcriptomic Landscape of HepG2 cells to Uncover Causal Gene Cytotoxicity Interactions Underlying Drug-Induced Liver Injury2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Lukas S. Wijaya, Attila Gábor, Iris Pot, Luca van de Have, Julio Sáez-Rodríguez, James L. Stevens, +3 more
1citations -
Trans-ancestry genome-wide association study identifies novel genetic mechanisms in rheumatoid arthritis2021 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Kazuyoshi Ishigaki, Saori Sakaue, Chikashi C. Terao, Yang Luo, Kyuto Sonehara, Kensuke Yamaguchi, +82 more
14citations -
Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis2022 Nature Genetics article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Kazuyoshi Ishigaki, Saori Sakaue, Chikashi C. Terao, Yang Luo, Kyuto Sonehara, Kensuke Yamaguchi, +84 more
374citations -
Research Review: Mechanisms of change and between‐family differences in parenting interventions for children with ADHD – an individual participant data meta‐analysis2025 Journal of Child Psychology and Psychiatry review Medicine Attention Deficit Hyperactivity Disorder Open access
Constantina Psyllou, Marjolein Luman, Barbara J. van den Hoofdakker, Saskia Van der Oord, Asma Aghebati, Bianca E. Boyer, +30 more
6citations -
Acute ischemic stroke or TIA despite DOAC treatment: the contribution of DOAC plasma levels to understand pathophysiological mechanisms2026 Therapeutic Advances in Neurological Disorders article Medicine Atrial Fibrillation Management and Outcomes Open access
Marcus Immanuel Rust, Merve Gözalan, Omid Nikoubashman, Martin Wiesmann, Matthias Imöhl, Jörg Bernhard Schulz, +2 more
0citations -
Patient-specific models link neurotransmitter receptor mechanisms with motor and visuospatial axes of Parkinson’s disease2023 Nature Communications article Medicine Parkinson's Disease Mechanisms and Treatments Open access
Ahmed Faraz Khan, Quadri Adewale, Sue‐Jin Lin, Tobias R. Baumeister, Yashar Zeighami, Félix Carbonell, +2 more
29citations -
Mechanisms of Melanoma Progression and Treatment Resistance: Role of Cancer Stem-like Cells2024 Cancers article Biochemistry, Genetics and Molecular Biology Melanoma and MAPK Pathways Open access
Youssef Al Hmada, Robert Thomas Brodell, Naji Kharouf, Thomas Wayne Flanagan, Abdulhadi A. AlAmodi, Sofie-Yasmin Hassan, +6 more
40citations