Papers matching “cardiomyocyte maturation” 37
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Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration2023 Science article Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Phong D. Nguyen, Iris Gooijers, Giulia Campostrini, Arie O. Verkerk, Hessel Honkoop, Mara Bouwman, +14 more
45citations -
Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease2020 Cell stem cell article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 13 patents
Elisa Giacomelli, Viviana Meraviglia, Giulia Campostrini, Amy Cochrane, Xu Cao, Ruben W.J. van Helden, +23 more
643citations -
YAP1 Contributes to The Development of Contractile Force and Sarcomere Maturation in Human Pluripotent Stem Cell-Derived Cardiomyocytes2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Vladimír Vinarský, Stefania Pagliari, Cristina Mazzotti, Katerina Jirakova, Zuzana Garlíková, Enrico Di Iuri, +9 more
1citations -
Human iPSC-cardiomyocyte-aggregate cell therapy in non-human primates and correlation of heart recovery with contractile and electrophysiological cardiomyocyte properties2026 Nature Communications article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Ina Gruh, Andreas Martens, Serghei Cebotari, Annette Schrod, Alexandra Haase, Caroline Halloin, +37 more
0citations -
Sequential defects in cardiac lineage commitment and maturation cause hypoplastic left heart syndrome2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Markus Krane, Martina Dreßen, Gianluca Santamaria, Ilaria My, Christine M. Schneider, Tatjana Dorn, +40 more
2citations -
YAP1 reactivation in cardiomyocytes following ECM remodelling contributes to the development of contractile force and sarcomere maturation2025 Cell Death Discovery article Biochemistry, Genetics and Molecular Biology Hippo pathway signaling and YAP/TAZ Open access
Vladimír Vinarský, Stefania Pagliari, Bacel Aldabash, Cristina Mazzotti, Katerina Jirakova, Zuzana Garlíková, +9 more
1citations -
Glycogen synthase kinase-3 inhibition and insulin enhance proliferation and inhibit maturation of human iPSC-derived cardiomyocytes via TCF and FOXO signaling2024 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Qianliang Yuan, Devin Verbueken, Rafeeh Dinani, Rosa Kim, Eric Schoger, Chloé D. Morsink, +8 more
7citations -
Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome2021 Circulation article Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Markus Krane, Martina Dreßen, Gianluca Santamaria, Ilaria My, Christine M. Schneider, Tatjana Dorn, +40 more
65citations -
Maturation of hiPSC-derived cardiomyocytes promotes adult alternative splicing of SCN5A and reveals changes in sodium current associated with cardiac arrhythmia
Giulia Campostrini, Georgios Kosmidis, Dorien Ward‐van Oostwaard, Richard P. Davis, Loukia Yiangou, Christiaan C. Veerman, +7 more
43citations -
In vitro approaches to mimic cardiac mechanical load dynamics for enhancing maturation and disease modelling2025 Cardiovascular Research article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Mariel Cano-Jorge, Jaap M. J. den Toonder, Ye Wang, R. C. Passier
5citations -
Maturation of hiPSC-derived cardiomyocytes in cardiac microtissues promotes adult alternative splicing of sodium channel revealing mutation effects associated with cardiac arrhythmia
Giulia Campostrini, Dorien Ward‐van Oostwaard, Georgios Kosmidis, Arie O. Verkerk, CR Bezzina, CL Mummery, +1 more
2citations -
Electrical stimulation: a missing key to promote maturation of human pluripotent stem cell-derived cardiomyocytes in three-dimensional cardiac tissues11citations
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Metabolic environment in vivo as a blueprint for differentiation and maturation of human stem cell-derived cardiomyocytes22citations
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High-throughput contractility analysis platform for drug-response evaluation of hiPSC-derived cardiac models based on dynamic frequency conditioning2026 Biosensors and Bioelectronics article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Paola Casti, Marcella Brescia, Luca Sala, Arianna Mencattini, Massimo Mastrangeli, Berend J. van Meer, +1 more
1citations -
Conditional immortalization of human cardiomyocytes for translational in vitro modelling of cardiovascular disease2022 Cardiovascular Research article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Niels J. Harlaar, Daniël A. Pijnappels, Antoine A.F. de Vries
1citations -
A New Versatile Platform for Assessment of Improved Cardiac Performance in Human-Engineered Heart Tissues2022 Journal of Personalized Medicine article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Marcelo C. Ribeiro, José M. Rivera‐Arbeláez, Carla Cofiño‐Fabrés, Verena Schwach, Rolf H. Slaats, Simone A. ten Den, +6 more
21citations -
Cardiac microtissues from human pluripotent stem cells recapitulate the phenotype of long-QT syndrome2021 Biochemical and Biophysical Research Communications article Medicine Cardiac electrophysiology and arrhythmias Open access
Elisa Giacomelli, Luca Sala, Dorien Ward‐van Oostwaard, Milena Bellin
19citations -
Formation of human cardiomyocytes is impaired in a fibrotic environment: unravelling human cardiac regeneration2021 European Heart Journal article Biochemistry, Genetics and Molecular Biology Congenital heart defects research
Arti Anushka Ramkisoensing, Juan Zhang, Niels J. Harlaar, Daniël A. Pijnappels, Antoine A.F. de Vries
1citations -
Generation, functional analysis and applications of isogenic three-dimensional self-aggregating cardiac microtissues from human pluripotent stem cells2021 Nature Protocols article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 12 patents
Giulia Campostrini, Viviana Meraviglia, Elisa Giacomelli, Ruben W.J. van Helden, Loukia Yiangou, Richard P. Davis, +3 more
109citations