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Bioprocess in‐line monitoring using Raman spectroscopy and Indirect Hard Modeling (IHM): A simple calibration yields a robust model2023 Biotechnology and Bioengineering article Chemistry Spectroscopy and Chemometric Analyses Open access
David Heinrich Müller, Carsten Flake, Thorsten Brands, Hans‐Jürgen Koß
17citations -
Scale‐down of CHO cell cultivation from shake flasks based on oxygen mass transfer allows application of parallelized, non‐invasive, and time‐resolved monitoring of the oxygen transfer rate in 48‐well microtiter plates2023 Biotechnology Journal article Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access
Nina Ihling, Christoph Berg, Richard Paul, Lara Pauline Munkler, Meeri Mäkinen, Véronique Chotteau, +1 more
6citations -
The Good pH probe: non-invasive pH in-line monitoring using Good buffers and Raman spectroscopy2023 Analytical and Bioanalytical Chemistry article Biochemistry, Genetics and Molecular Biology Spectroscopy Techniques in Biomedical and Chemical Research Open access
David Heinrich Müller, Marieke Börger, Julia Thien, Hans‐Jürgen Koß
5citations -
Advancing 2D fluorescence online monitoring in microtiter plates by separating scattered light and fluorescence measurement, using a tunable emission monochromator2023 Biotechnology and Bioengineering article Chemistry Spectroscopy and Chemometric Analyses Open access
Christoph Berg, Muthia Dewi Alawiyah, Maurice Finger, Nina Ihling, Olivier Paquet‐Durand, Bernd Hitzmann, +1 more
1citations -
Online 2D Fluorescence Monitoring in Microtiter Plates Allows Prediction of Cultivation Parameters and Considerable Reduction in Sampling Efforts for Parallel Cultivations of Hansenula polymorpha
Christoph Berg, Nina Ihling, Maurice Finger, Olivier Paquet‐Durand, Bernd Hitzmann, Jochen Büchs
10citations -
Non-invasive online monitoring of polyol lipid production with Aureobasidium pullulans using fluorescence measurement2026 Biotechnology and Bioprocess Engineering article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Max Daniel Dicke, Noémie L. J. Carls, Philipp Kohl, Marie R. E. Dielentheis-Frenken, Lars M. Blank, Valentin Steier, +3 more
0citations -
In situ adsorption of itaconic acid from fermentations of Ustilago cynodontis improves bioprocess efficiency2023 Biotechnology for Biofuels and Bioproducts article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Johannes Pastoors, Alexander Deitert, Carina V. Michel, Karsten Günster, Maurice Finger, Jordy Hofstede, +6 more
18citations -
Optimized prodigiosin production with Pseudomonas putida KT2440 using parallelized noninvasive online monitoring2022 Biotechnology Progress article Biochemistry, Genetics and Molecular Biology Microbial Metabolism and Applications Open access
Carl Brehl, Hannah U. C. Brass, Clara Lüchtrath, Nina Ihling, Thomas Claßen, Jörg Pietruszka, +1 more
12citations -
Sampling-free investigation of microbial carbon source preferences on renewable feedstocks via online monitoring of oxygen transfer rate2024 Bioprocess and Biosystems Engineering article Engineering Fluid Dynamics and Mixing Open access
Luca Antonia Grebe, Paul Richter, Torben Altenkirch, Marcel Mann, Markus Müller, Jochen Büchs, +1 more
2citations -
Non-invasive online monitoring of polyol lipid production with Aureobasidium pullulans using fluorescence measurement2026 Biotechnology and Bioprocess Engineering article Environmental Science Microbial bioremediation and biosurfactants Open access
Max Daniel Dicke, Noémie L. J. Carls, Philipp Kohl, Marie R. E. Dielentheis-Frenken, Lars M. Blank, Valentin Steier, +3 more
0citations -
In Vivo Online Monitoring of Intracellular Lipid Accumulation in Ustilago maydis2025 Engineering in Life Sciences article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Kira Müntjes, Lesley Plücker, Magnus Philipp, Paul Richter, Marcel Mann, Michael Feldbrügge, +1 more
1citations -
Assessing the capabilities of 2D fluorescence monitoring in microtiter plates with data-driven modeling for secondary substrate limitation experiments of Hansenula polymorpha2023 Journal of Biological Engineering article Chemistry Spectroscopy and Chemometric Analyses Open access
Christoph Berg, Laura Herbst, Lisa Gremm, Nina Ihling, Olivier Paquet‐Durand, Bernd Hitzmann, +1 more
3citations -
Need for speed: evaluation of dilute and shoot-mass spectrometry for accelerated metabolic phenotyping in bioprocess development2021 Analytical and Bioanalytical Chemistry article Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access
Alexander M. Reiter, Laura Herbst, Wolfgang Wiechert, Marco Oldiges
11citations -
Non‐invasive and time‐resolved measurement of the respiration activity of Chinese hamster ovary cells enables prediction of key culture parameters in shake flasks2022 Biotechnology Journal article Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access
Nina Ihling, Lara Pauline Munkler, Richard Paul, Christoph Berg, Britta Reichenbächer, Marvin Kadisch, +2 more
20citations -
XyloSenS – FRET‐basierte Biosensoren zur online In‐vitro‐ Überwachung der Substratkonzentration von Kultivierungen2020 Chemie Ingenieur Technik article Biochemistry, Genetics and Molecular Biology Advanced Fluorescence Microscopy Techniques
David Vonester, Julia Otten, Martina Pohl, Wolfgang Wiechert, Jochen Büchs
2citations