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Bioprocess in‐line monitoring using Raman spectroscopy and Indirect Hard Modeling (IHM): A simple calibration yields a robust model2023 Biotechnology and Bioengineering article Chemistry Spectroscopy and Chemometric Analyses Open access
David Heinrich Müller, Carsten Flake, Thorsten Brands, Hans‐Jürgen Koß
17citations -
A novel multiparameter sensor for shake flask cultivations: Online biomass, dissolved oxygen, and fluorescence monitoring for comprehensive bioprocess characterization2025 Biotechnology Progress article Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access
Lara Strehl, Kyra Hoffmann, Marcel Mann, Jørgen Barsett Magnus
1citations -
High‐sensitivity real‐time monitoring of pH and respiration activity unveils metabolic dynamics in shake flask cultures2024 Biotechnology Progress article Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access
Burak Sarikaya, Karsten Günster, Luca Antonia Grebe, Eva Forsten, Katharina Hürter, Jochen Büchs, +1 more
4citations -
Machine learning in bioprocess development: From promise to practice2022 arXiv (Cornell University) preprint Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access
Laura M. Helleckes, Johannes Hemmerich, Wolfgang Wiechert, Eric von Lieres, Alexander Grünberger
4citations -
Scale‐down of CHO cell cultivation from shake flasks based on oxygen mass transfer allows application of parallelized, non‐invasive, and time‐resolved monitoring of the oxygen transfer rate in 48‐well microtiter plates2023 Biotechnology Journal article Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access
Nina Ihling, Christoph Berg, Richard Paul, Lara Pauline Munkler, Meeri Mäkinen, Véronique Chotteau, +1 more
6citations -
Generating in-depth process knowledge by Computational Fluid Dynamics and a novel online monitoring technique for shake flasks0citations
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Advancing 2D fluorescence online monitoring in microtiter plates by separating scattered light and fluorescence measurement, using a tunable emission monochromator2023 Biotechnology and Bioengineering article Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access
Christoph Berg, Muthia Dewi Alawiyah, Maurice Finger, Nina Ihling, Olivier Paquet‐Durand, Bernd Hitzmann, +1 more
1citations -
Online 2D Fluorescence Monitoring in Microtiter Plates Allows Prediction of Cultivation Parameters and Considerable Reduction in Sampling Efforts for Parallel Cultivations of Hansenula polymorpha
Christoph Berg, Nina Ihling, Maurice Finger, Olivier Paquet‐Durand, Bernd Hitzmann, Jochen Büchs
10citations -
Non-invasive online monitoring of polyol lipid production with Aureobasidium pullulans using fluorescence measurement2026 Biotechnology and Bioprocess Engineering article Agricultural and Biological Sciences Polysaccharides Composition and Applications Open access
Max Daniel Dicke, Noémie L. J. Carls, Philipp Kohl, Marie R. E. Dielentheis-Frenken, Lars M. Blank, Valentin Steier, +3 more
0citations -
Expanding Metabolic Online Monitoring Capabilities in 96‐Deepwell Microtiter Plates by Combining Optoelectronic O 2 and CO 2 Sensors2026 Biotechnology and Bioengineering article Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access
Robert Dinger, David Pfeifer, David Flitsch, Clemens Lattermann, Sergey M. Borisov, Jochen Büchs
0citations -
Machine learning in bioprocess development: from promise to practice2022 Trends in biotechnology review Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access cited by 1 patent
Laura M. Helleckes, Johannes Hemmerich, Wolfgang Wiechert, Eric von Lieres, Alexander Grünberger
166citations -
Simultaneous online monitoring of viscosity and oxygen transfer rate in shake flask cultures2025 Journal of Biological Engineering article Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access
René Hanke, Michaela Sieben, Maurice Finger, Kilian Schnoor, Simon Jeßberger, Julia Weyand, +5 more
2citations -
In situ adsorption of itaconic acid from fermentations of Ustilago cynodontis improves bioprocess efficiency2023 Biotechnology for Biofuels and Bioproducts article Engineering Biofuel production and bioconversion Open access
Johannes Pastoors, Alexander Deitert, Carina V. Michel, Karsten Günster, Maurice Finger, Jordy Hofstede, +6 more
18citations -
Optimized prodigiosin production with Pseudomonas putida KT2440 using parallelized noninvasive online monitoring2022 Biotechnology Progress article Biochemistry, Genetics and Molecular Biology Microbial Metabolism and Applications Open access
Carl Brehl, Hannah U. C. Brass, Clara Lüchtrath, Nina Ihling, Thomas Claßen, Jörg Pietruszka, +1 more
12citations -
Pitfalls in Early Bioprocess Development Using Shake Flask Cultivations2025 Engineering in Life Sciences article Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access
Gesa Brauneck, Dominik Engel, Luca Antonia Grebe, Philipp Georg Lichtenberg, Anne Neuß, Marcel Mann, +1 more
18citations -
Sampling-free investigation of microbial carbon source preferences on renewable feedstocks via online monitoring of oxygen transfer rate2024 Bioprocess and Biosystems Engineering article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Luca Antonia Grebe, Paul Richter, Torben Altenkirch, Marcel Mann, Markus Müller, Jochen Büchs, +1 more
2citations -
Non-invasive online monitoring of polyol lipid production with Aureobasidium pullulans using fluorescence measurement2026 Biotechnology and Bioprocess Engineering article Agricultural and Biological Sciences Polysaccharides Composition and Applications Open access
Max Daniel Dicke, Noémie L. J. Carls, Philipp Kohl, Marie R. E. Dielentheis-Frenken, Lars M. Blank, Valentin Steier, +3 more
0citations -
In Vivo Online Monitoring of Intracellular Lipid Accumulation in Ustilago maydis2025 Engineering in Life Sciences article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Kira Müntjes, Lesley Plücker, Magnus Philipp, Paul Richter, Marcel Mann, Michael Feldbrügge, +1 more
1citations