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Secondary bile acid production by gut bacteria promotes Western diet-associated colorectal cancer2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Esther Wortmann, Annika Oßwald, David Wylensek, Stephanie Kuhls, Olivia I. Coleman, Quinten R. Ducarmon, +17 more
4citations -
Genome-wide association study reveals loci with sex-specific effects on plasma bile acids2022 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Arianna Landini, Dariush Ghasemi-Semeskandeh, Åsa Johansson, Shahzad Ahmad, Gerhard Liebisch, Carsten Gnewuch, +14 more
0citations -
A physiologically-based model of bile acid metabolism in mice2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Drug Transport and Resistance Mechanisms Open access
Bastian Kister, Alina Viehof, Ulrike Elisabeth Rolle-Kampczyk, Annika Schwentker, Nicole Simone Treichel, Susan A. V. Jennings, +6 more
2citations -
Microbially-conjugated Bile Salts Found in Human Bile Activate the Bile Salt Receptors TGR5 and FXR2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Drug Transport and Resistance Mechanisms Open access
Martin Leníček, Raphael Silvanus Haider, Arno Claßen, Hans van Eijk, Kiran V.K. Koelfat, Gregory van der Kroft, +5 more
0citations -
The FXR agonist obeticholic acid does not stimulate liver regeneration in hepatectomized mice2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver physiology and pathology Open access
Kim M.C. van Mierlo, Carola Dahrenmöller, Valérie Lebrun, Peter L. M. Jansen, Cornelis H.C. Dejong, Isabelle Anne Leclercq, +2 more
0citations -
Increasing plasma bile salt levels with Bulevirtide alleviates DSS-induced colitis and LPS-induced inflammation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease
Thuc-Anh Nguyen, Reinout L.P. Roscam Abbing, Pim J. Koelink, Joost M. Lambooij, Wietse In het Panhuis, Dirk Rudi de Waart, +9 more
0citations -
The Gut Metabolism is altered in patients with CRB1 -associated inherited retinal degeneration2024 medRxiv preprint Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Lude Moekotte, Joke Helena de Boer, Sanne Hiddingh, Bram Gerritsen, Jutta Lintelmann, Alexander Cecil, +5 more
0citations -
Novel biomarkers for glycaemic deterioration in type 2 diabetes: an IMI RHAPSODY study2021 medRxiv preprint Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access
Roderick C. Slieker, Louise A. Donnelly, Livia López–Noriega, Hermine Muniangi-Muhitu, Elina Akalestou, Mahsa Sheikh, +49 more
3citations -
The Metabolomic Signature of Stressful Life Events2026 medRxiv preprint Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access
Yumeng Tian, Ruifang Li‐Gao, Tahani Alshehri, Christopher R. Brydges, Matthias Arnold, Siamak MahmoudianDehkordi, +11 more
0citations -
Genome-wide Association Studies of Missing Metabolite Measures: Results From Two Population-based Studies2024 medRxiv preprint Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access
Tariq O. Faquih, Mohammed Aslam Imtiaz, Valentina Talevi, Elvire Nadieh Landstra, Astrid van Hylckama Vlieg, Ruifang Li‐Gao, +7 more
0citations -
Comparative metabolomics and microbiome analysis of Ethanol vs. OMNImet/gene®•GUT fecal stabilization2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Heidi Isokääntä, Lucas Pinto da Silva, Naama Karu, Teemu Kallonen, Anna‐Katariina Aatsinki, Thomas Hankemeier, +9 more
2citations -
Metabolic Alteration in Oxylipins and Endocannabinoids Point to an Important Role for Soluble Epoxide Hydrolase and Inflammation in Alzheimer’s Disease - Finding from Alzheimer’s Disease Neuroimaging Initiative2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Alzheimer's disease research and treatments Open access
Kamil Borkowski, Chunyuan Yin, Alida S. D. Kindt, Nuanyi Liang, Elizabeth C. M. de Lange, Colette Blach, +3 more
3citations -
Physiologically relevant Multi-Omics Flux Analysis Reveals Metabolic Mechanisms of drug-Induced Liver Toxicity2026 Research Square preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Zita I. T. A. Soons, Ahenk Zeynep Sayin, Lars M. Blank, Adrian B. Roth, Marco Oldiges, Henrik Cordes, +1 more
0citations -
Hepatocellular Loss of Mtor Aggravates Tumor Burden in Nonalcoholic Steatohepatitis-Related Hcc2023 SSRN Electronic Journal preprint Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Andreas Kroh, Jeanette Walter, Athanassios Fragoulis, Diana Möckel, Twan Lammers, Fabian M. Kiessling, +10 more
0citations -
Development of a mouse model for postresectional liver failure2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver physiology and pathology Open access
Kim M.C. van Mierlo, C. Van Himbeeck, Valérie Lebrun, Peter L. M. Jansen, Cornelius H.C. Dejong, Isabelle Anne Leclercq, +2 more
0citations -
Proteogenomic and observational evidence implicate ANGPTL4 as a potential therapeutic target for colorectal cancer prevention2024 medRxiv preprint Biochemistry, Genetics and Molecular Biology Cancer, Lipids, and Metabolism Open access
James Yarmolinsky, Matthew A. Lee, Evelyn Lau, Ferrán Moratalla-Navarro, Emma E. Vincent, Ruifang Li‐Gao, +21 more
1citations -
Integration of In Vitro and In Silico Approaches Enables Prediction of Drug-Induced Liver Injury2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
René Geci, Ahenk Zeynep Sayin, Stephan Schaller, Lars Kuepfer
0citations
19 results