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Novel high throughput 3D ECM remodeling assay identifies MEK as key driver of fibrotic fibroblast activity2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Chen‐Yi Liao, Jasmijn H.M. Hundscheid, Justin Crawford, Peter ten Dijke, Beatrice Coorneaert, Erik H.J. Danen
0citations -
Ad26.COV2.S elicited neutralizing activity against Delta and other SARS-CoV-2 variants of concern2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access
Mandy A. C. Jongeneelen, Krisztián Kaszás, Daniel Veldman, Jeroen Huizingh, Remko van der Vlugt, Theo G. Schouten, +15 more
45citations -
Metagenomics Combined with Activity-Based Proteomics Point to Gut Bacterial Enzymes that Reactivate Mycophenolate2022 medRxiv preprint Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Joshua B. Simpson, Josh J. Sekela, Amanda L. Graboski, Valentina Borlandelli, Natalie K. Barker, Alicia A. Sorgen, +8 more
6citations -
Neutralizing antibodies elicited by the Ad26.COV2.S COVID-19 vaccine show reduced activity against 501Y.V2 (B.1.351), despite protection against severe disease by this variant2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access
Penny L. Moore, Thandeka Moyo-Gwete, Tandile Hermanus, Prudence Kgagudi, Frances Ayres, Zanele Makhado, +9 more
16citations -
Asymptomatic gut colonization by extended-spectrum beta-lactamase-producing Escherichia coli is not associated with an altered gut microbiome or metabolome in Dutch adults2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Quinten R. Ducarmon, Romy Daniëlle Zwittink, Roel P J Willems, Aswin Verhoeven, Sam Nooij, Fiona R.M. van der Klis, +6 more
1citations -
Methyl substituted β –lactam framework based antibiotics and β -lactamase inhibitors: Proof of concept by computations2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Chemistry Synthesis of β-Lactam Compounds Open access
Vaishali Thakkur, Chandan Kumar Das, Shivani Verma, Suman Saha, Nisanth N. Nair
0citations -
Myofibre-specific knockout of TGF-β type I receptors triggers muscle hypertrophy and promotes contraction and oxidative metabolism2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders
Andi Shi, Michèle MG Hillege, Carla Offringa, Gang Wu, Tymour Forouzanfar, Willem M.H. Hoogaars, +2 more
1citations -
SMAD2: Regulatory junction of TGF-β and antigen signaling in mast cells2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Gina Bronneberg, Steffen K. Meurer, Marlies Kauffmann, Chao‐Chung Kuo, Christian Liedtke, Ralf Weiskirchen, +1 more
1citations -
Novel Cephalosporin Conjugates Display Potent and Selective Inhibition of IMP Type Metallo-β-Lactamases2020 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access
Kamaleddin H. M. E. Tehrani, Nicola Wade, Vida Mashayekhi, Nora C. Brüchle, Willem Jespers, Koen Voskuil, +4 more
0citations -
Novel Cephalosporin Conjugates Display Potent and Selective Inhibition of IMP Type Metallo-β-Lactamases2020 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access
Kamaleddin H. M. E. Tehrani, Nicola Wade, Vida Mashayekhi, Nora C. Brüchle, Willem Jespers, Koen Voskuil, +4 more
0citations -
The modulatory role of early-life experiences and sex on cognitive resilience in APP/PS1 mice over time2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Alzheimer's disease research and treatments Open access
Maria Carrigan, Jeniffer Sanguino‐Gómez, Melis Bayer-Var, Olga Minko, Alise Bobkova, Eva Ruzicka, +6 more
0citations -
Modulating effects of FGF12 variants on Na V 1.2 and Na V 1.6 associated with Developmental and Epileptic Encephalopathy and Autism Spectrum Disorder2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Simone Seiffert, Manuela Pendziwiat, Tatjana Bierhals, Himanshu Goel, Niklas Schwarz, Amelie T. van der Ven, +5 more
2citations -
Mechanistic Investigations of Metallo-β-Lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition2020 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access
Nicola Wade, Kamaleddin H. M. E. Tehrani, Nora C. Brüchle, Matthijs J. van Haren, Vida Mashayekhi, Nathaniel I. Martin
0citations -
Modulation of Giant Depolarizing Potentials (GDPs) in Human Large Basket Cells by Norepinephrine and Acetylcholine2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Neural dynamics and brain function Open access
Danqing Yang, Guanxiao Qi, Jonas Ort, Victoria Sofie Witzig, Aniella Bak, Daniel Delev, +2 more
0citations -
Pro-domain-dependent folding and co-receptor-mediated targeting to optimize an antagonistic TGF-β monomer for gene-based delivery2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Łukasz Wieteska, Cynthia S. Hinck, Ananya Mukundan, Troy C. Krzysiak, Maarten van Dinther, Thibault Vantieghem, +4 more
0citations -
LRH-1/NR5A2 Activation Rewires Immunometabolism Blunting Inflammatory Immune Cell Progression in Individuals with Type 1 Diabetes and Enhances Human Islet Function in Mice2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access
Nadia Cobo‐Vuilleumier, Silvia Rodríguez-Fernández, Livia López–Noriega, Petra Isabel Lorenzo, JM Franco, CC Lachaud, +22 more
0citations -
TGFβ signaling in cancer-associated fibroblasts drives a hepatic gp130-dependent pro-metastatic inflammatory program in CMS4 colorectal cancer subtype2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Tom J. Harryvan, Subinuer Abudukelimu, Imke Stouten, EJ van der Wel, Kristiaan Lenos, OJ Sansom, +1 more
0citations -
Surface topography is a context-dependent activator of TGF-β signaling in mesenchymal stem cells2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Steven Vermeulen, Nadia J. T. Roumans, Floris Honig, Aurélie Carlier, Dennie G.A.J. Hebels, Aysegul Dede Eren, +3 more
0citations