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Autoreactive B cells in rheumatoid arthritis consist of activated CXCR3+ memory B cells and plasmablasts2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Rheumatoid Arthritis Research and Therapies Open access
Sanne Reijm, Joanneke C. Kwekkeboom, Nienke J. Blomberg, Jolien Suurmond, Diane van der Woude, René E. M. Toes, +1 more
1citations -
Increased Phosphorylation of Intracellular Signaling Molecules Indicates Continuous Activation of Human Autoreactive B‐Cells2025 European Journal of Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Sanne Kroos, Nienke J. Blomberg, Joanneke C. Kwekkeboom, Rudi W. Hendriks, Odilia B. J. Corneth, René E. M. Toes, +1 more
4citations -
Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis2020 Science Translational Medicine article Medicine Rheumatoid Arthritis Research and Therapies Open access
Hendy Kristyanto, Nienke J. Blomberg, Linda M. Slot, Ellen I. H. van der Voort, Priscilla F. Kerkman, Aleida M. Bakker, +8 more
117citations -
Targeting autoreactive B cells in rheumatoid arthritis through MHC class I-presented BCR-derived neo-epitopes2026 Journal of Autoimmunity article Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access
Renee van de Wetering, Arieke S. B. Kampstra, Michel G.D. Kester, Rayman T.N. Tjokrodirijo, Arnoud H. de Ru, Peter A. van Veelen, +3 more
0citations -
Multifunctional, Multivalent PIC Polymer Scaffolds for Targeting Antigen-Specific, Autoreactive B Cells2022 ACS Biomaterials Science & Engineering article Chemistry Advanced Polymer Synthesis and Characterization Open access
Hendy Kristyanto, Miles D. Holborough-Kerkvliet, Lianne P. W. M. Lelieveldt, Yvonne L Bartels, Roel Hammink, Karin Anna van Schie, +3 more
11citations -
Autoreactive B cells remain active despite clinical disease control in rheumatoid arthritis2024 Journal of Autoimmunity article Medicine Rheumatoid Arthritis Research and Therapies Open access
Sam Neppelenbroek, Nienke J. Blomberg, Arieke S. B. Kampstra, Joost G.K. van der Hem, Tom W. J. Huizinga, René E. M. Toes, +1 more
10citations -
Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation2022 Science Advances article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Theresa Kissel, Changrong Ge, Lise Hafkenscheid, Joanneke C. Kwekkeboom, Linda M. Slot, Marco Cavallari, +18 more
77citations -
Effect of Antigen Valency on Autoreactive B-Cell Targeting2023 Molecular Pharmaceutics article Medicine Rheumatoid Arthritis Research and Therapies Open access
Margot J. van Weijsten, Kevin R. Venrooij, Lianne P. W. M. Lelieveldt, Theresa Kissel, Erik van Buijtenen, Floris J. van Dalen, +3 more
4citations -
Autoreactive B cell responses targeting nuclear antigens in systemic sclerosis: Implications for disease pathogenesis2022 Seminars in Arthritis and Rheumatism article Medicine Systemic Sclerosis and Related Diseases Open access cited by 2 patents
Sophie I E Liem, Sam Neppelenbroek, Cynthia M. Fehres, Corrie M. Wortel, René E. M. Toes, Tom W. J. Huizinga, +2 more
16citations -
Clonal autoantibodies identify microbial antigen as trigger of autoreactive B cells in systemic sclerosis2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Systemic Sclerosis and Related Diseases Open access
Sam Neppelenbroek, Sophie I E Liem, Theo van Laar, Eva M. Hoekstra, Corrie M. Wortel, E. W. Nivine Levarht, +5 more
0citations -
POS0403 DYNAMIC CHANGES IN AUTOREACTIVE MEMORY B CELLS IN RHEUMATOID ARTHRITIS: KEY TO UNDERSTANDING IMMUNOLOGICAL DISEASE ACTIVITY2022 Annals of the Rheumatic Diseases article Medicine Rheumatoid Arthritis Research and Therapies Open access
Nienke J. Blomberg, H. Kristyanto, M. Verstappen, S. Neppelenbroek, Arieke S. B. Kampstra, A. van der Helm-van Mil, +2 more
0citations -
AB0022 AUTOREACTIVE B CELLS IN RHEUMATOID ARTHRITIS DISPLAY AN ACTIVATED PHENOTYPE OF RECENT ANTIGEN EXPOSURE2021 Annals of the Rheumatic Diseases conference-abstract Medicine Rheumatoid Arthritis Research and Therapies
Nienke J. Blomberg, Hendy Kristyanto, Tom W. J. Huizinga, René E. M. Toes, Hans Ulrich Scherer
0citations -
Light chain skewing in autoantibodies and B-cell receptors of the citrullinated antigen-binding B-cell response in rheumatoid arthritis2021 PLoS ONE article Medicine Rheumatoid Arthritis Research and Therapies Open access cited by 1 patent
Linda M. Slot, Rochelle D. Vergroesen, Priscilla F. Kerkman, Ellen Magadalena Staudinger, Sanne Reijm, Hugo J. van Dooren, +4 more
9citations