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High-resolution cryo-EM structure of integrin αIIbβ3 bound to disease-causing maternal HPA-1a antibody that blocks integrin activation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cell Adhesion Molecules Research Open access
José M. de Pereda, Wendy Stam, Marcos Gragera, Femke S. van der Meer, Francisco Javier Chichón, Eleftherios Zarkadas, +4 more
0citations -
DNA nanostructure-templated antibody complexes provide insights into the geometric requirements of human complement cascade activation2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Complement system in diseases Open access
Leoni Abendstein, Willem E. M. Noteborn, Luc S. Veenman, Douwe J. Dijkstra, Fleur S. van de Bovenkamp, Leendert Adrianus Trouw, +1 more
0citations -
Mechanistic Interpretability of Antibody Language Models Using SAEs2025 arXiv (Cornell University) preprint Computer Science Explainable Artificial Intelligence (XAI) Open access
Oliver M. Turnbull, Anisha Parsan, Nithin Parsan, John Jeongseok Yang, Anna L. Beukenhorst, Charlotte Mary Deane
0citations -
Patient-derived monoclonal anti-HPA-1a can induce platelet activation through FcγRIIa2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Platelet Disorders and Treatments Open access
Janita J. Oosterhoff, Suze Rosanne van Brummelen, Marco Giulini, Iris M. De Cuyper, Remco Visser, Rick Kapur, +11 more
0citations -
Structural basis for surface activation of the classical complement cascade by the short pentraxin C-reactive protein2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Biomarkers in Disease Mechanisms Open access cited by 2 patents
Dylan P. Noone, Marjolein M. E. Isendoorn, Sebastiaan M. W. R. Hamers, Mariska E. Keizer, Jip Wulffelé, Tijn T. van der Velden, +4 more
3citations -
NanoDesigner: Resolving the complex–CDR interdependency with iterative refinement2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Monoclonal and Polyclonal Antibodies Research Open access
Melissa Maria Rios Zertuche, Şenay Kafkas, Dominik Renn, Magnus Rueping, Robert Hoehndorf
0citations -
Assessing and improving the validity of COVID-19 autopsy studies - a multicenter approach to establish essential standards for immunohistochemical and ultrastructural analyses
Susanne Krasemann, Carsten Dittmayer, Saskia Freifrau von Stillfried, Jenny Meinhardt, Fabian Heinrich, Katrin Hartmann, +26 more
3citations -
Structural and functional characterization of SARS-CoV-2 RBD domains produced in mammalian cells2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access
Christoph Gstöttner, Tao Zhang, Anja Resemann, Sophia Ruben, Stuart Pengelley, Detlev Suckau, +3 more
5citations -
Fi-score: a novel approach to characterise protein topology and aid in drug discovery studies2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access
Austė Kanapeckaitė, Claudia Beaurivage, MATTHEW J. HANCOCK, Erik Verschueren
2citations -
IgA displays site- and subclass-specific glycoform differences despite equal glycoenzyme expression2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
David Falck, Maria V Sokolova, Carolien A. M. Koeleman, Vanessa Irumva, Philipp Kirchner, Sebastian R. Schulz, +8 more
0citations -
Vaccine Elicitation of HIV-1 Neutralizing Antibodies Against Both V2 Apex and Fusion Peptide in Rhesus Macaques2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology HIV Research and Treatment Open access
Hongying Duan, Joseph P. Nkolola, Shuishu Wang, Jayeshbhai Chaudhari, I‐Ting Teng, Christy L. Lavine, +38 more
0citations -
Autoantibodies against Progranulin and IL-1 receptor antagonist due to immunogenic posttranslational isoforms contribute to hyperinflammation in critically ill COVID-192021 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine COVID-19 Clinical Research Studies Open access
Lorenz Thurner, Natalie Fadle, Moritz Bewarder, Igor Age Kos, Evi Regitz, Bernhard Thurner, +52 more
10citations -
Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access
Xiaodi Yu, Jarek Juraszek, Lucy Rutten, Mark J. G. Bakkers, Sven Blokland, Niels J. F. van den Broek, +9 more
1citations -
Immunoglobulin G1 Fc glycosylation as an early hallmark of severe COVID-192021 medRxiv preprint Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Tamás Pongrácz, Jan Nouta, Wenjun Wang, Krista E. van Meijgaarden, Federica Linty, Gestur Vidarsson, +7 more
8citations -
Co-translational folding of the first transmembrane domain of ABC-transporter CFTR is supported by assembly with the first cytosolic domain2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cystic Fibrosis Research Advances Open access
Bertrand Kleizen, Marcel van Willigen, Marjolein Mijnders, Florence Peters, Magda Grudniewska, Tamara Hillenaar, +5 more
2citations -
A conserved glycan motif overcomes antigenic variation inducing broadly reactive antibodies against the zoonotic pathogen Streptococcus suis2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Streptococcal Infections and Treatments Open access
Yao Shi, Göran Widmalm, Charlotte Sorieul, Thomas J. Roodsant, Jeffrey S. Rush, Natalia Korotkova, +15 more
0citations -
Clonal autoantibodies identify microbial antigen as trigger of autoreactive B cells in systemic sclerosis2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Systemic Sclerosis and Related Diseases Open access
Sam Neppelenbroek, Sophie I E Liem, Theo van Laar, Eva M. Hoekstra, Corrie M. Wortel, E. W. Nivine Levarht, +5 more
0citations
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