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Divergent CD27 expression marks the Treg induction trajectory2026 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Chelsea Gootjes, Maurits G. Staal, Diahann T. S. L. Jansen, Antoinette M. Joosten, Jaap Jan Zwaginga, Bart O. Roep, +1 more
0citations -
Generation of Regulatory T Cells Against Islet Neoantigen2026 European Journal of Immunology article Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access
Nicoline H. M. den Hollander, Chelsea Gootjes, Maurits G. Staal, Antoinette M. Joosten, Tatjana Nikolić, Bart O. Roep, +1 more
0citations -
IL-2 mutein-engrafted antibody MHS552 selectively expands functional regulatory T cells in nonclinical models and healthy participants2026 Nature Communications article Immunology and Microbiology T-cell and B-cell Immunology Open access
Igor Radanović, Michael DiDonato, Anouk C. Meijs, Yaiza Diaz De Durana, Andrea Kießling, Thierry Flandre, +31 more
0citations -
IL-21R blockade reduces atherosclerosis development in LDLR-/- mice2022 Atherosclerosis article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
R. Postel, Vincent T.H.B.M. Smit, J. De Mol, Mireia N. A. Bernabé Kleijn, M.J.M. De Jong, L. Delfos, +4 more
1citations -
Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive atherosclerosis2024 Nature Cardiovascular Research article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Yvonne Döring, Emiel P. C. van der Vorst, Yi Yan, Carlos Neideck, Xavier Blanchet, Yvonne J. F. M. Jansen, +22 more
34citations -
Regulatory T Cell Depletion Using a CRISPR Fc-Optimized CD25 Antibody2022 International Journal of Molecular Sciences article Immunology and Microbiology T-cell and B-cell Immunology Open access
Marit J van Elsas, Johan M. S. van der Schoot, Alexander Bartels, Kas Steuten, Duco van Dalen, Zacharias Wijfjes, +5 more
5citations -
AMPK activation induces RALDH+ tolerogenic dendritic cells by rewiring glucose and lipid metabolism2024 The Journal of Cell Biology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Eline Constance Brombacher, Thiago A. Patente, Alwin J. van der Ham, Tijmen J.A. Moll, Frank Otto, Esther A. Zaal, +6 more
23citations -
Soluble and EV-bound CD27 act as antagonistic biomarkers in patients with solid tumors undergoing immunotherapy2024 Journal of Experimental & Clinical Cancer Research article Medicine Cancer Immunotherapy and Biomarkers Open access
Joao Gorgulho, Sven Heiko Loosen, Ramsha Masood, Franziska Giehren, Francesca Pagani, Gustav Buescher, +26 more
12citations -
Defining nature, responses and drivers of regulatory- and conventional CD4+ T cells in the human term decidua2026 Frontiers in Immunology article Immunology and Microbiology Reproductive System and Pregnancy Open access
Lotte J. Verleng, Julia Busselaar, Mark Mensink, Ellen Schrama, Hanneke Kapsenberg, Carin van der Keur, +5 more
0citations -
Intestinal Regulatory T Cells as Specialized Tissue-Restricted Immune Cells in Intestinal Immune Homeostasis and Disease2021 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Justin Jacobse, Jing Li, Edmond H.H.M. Rings, Janneke N. Samsom, Jeremy A. Goettel
94citations -
Precision Engineering of an Anti-HLA-A2 Chimeric Antigen Receptor in Regulatory T Cells for Transplant Immune Tolerance2021 Frontiers in Immunology article Medicine CAR-T cell therapy research Open access cited by 6 patents
Yannick D. Müller, Leonardo M. R. Ferreira, Émilie Ronin, Patrick Ho, Vinh Q. Nguyen, Gaetano Faleo, +10 more
109citations -
Distinct roles for interleukin-23 receptor signaling in regulatory T cells in sporadic and inflammation-associated carcinogenesis2024 Frontiers in Oncology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Justin Jacobse, Jennifer M. Pilat, Rachel E. Brown, Aaron Kwag, Matthew A. Buendia, Yash A. Choksi, +5 more
8citations -
Age Distribution of Multiple Functionally Relevant Subsets of CD4+ T Cells in Human Blood Using a Standardized and Validated 14-Color EuroFlow Immune Monitoring Tube2020 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Vitor Botafogo, Martín Pérez‐Andrés, María Jara‐Acevedo, Paloma Bárcena, Georgiana Emilia Grigore, Alejandro Hernández-Delgado, +16 more
60citations